Results 51 to 60 of about 42,451 (299)
PLoS ONE, 2011 The PML tumor suppressor is the founding component of the multiprotein nuclear structures known as PML nuclear bodies (PML-NBs), which control several cellular functions including apoptosis and antiviral effects.
Feroz Sarkari +3 more
doaj +1 more source
, 2016 Epithelial–mesenchymal transition (EMT) is a key event that is involved in the invasion and dissemination of cancer cells. Although typically considered as having tumour-suppressive properties, transforming growth factor (TGF)-β signalling is altered ...
Powe, DG +25 more
core +1 more source
Advanced Engineering Materials, Volume 27, Issue 6, March 2025.ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Crosstalk between p53 modifiers at PML bodies
Molecular & Cellular Oncology, 2018 Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage.
Sonja Matt, Thomas G Hofmann
doaj +1 more source
PML-nuclear body formation is impaired in deletion mutant PML-RARA-expressing cells.
, 2018 (A) PML/RARA degradation upon RA treatment in Wt-PML-RARA- and mutant-PML-RARA-transduced cells was analyzed by Western blot using anti-FLAG antibody. The cells were treated with 1 μM of ATRA or tamibarotene for 12 hours.
Yohei Yamaguchi (716799) +13 more
core +1 more source
The use of fluorescence microscopy to study the association between herpesviruses and intrinsic resistance factors [PDF]
, 2011 Intrinsic antiviral resistance is a branch of antiviral defence that involves constitutively expressed cellular proteins that act within individual infected cells.
Roger D. Everett +3 more
core +1 more source
Low‐Profile, High‐Gain GRIN RF Lenses via Multi‐Material Vat Photopolymerization
Advanced Functional Materials, EarlyView.We investigate the opportunity of leveraging multi‐material vat photopolymerization printing to manufacture intricate lenses exhibiting permittivity gradients that can increase signal gain in transmitted radiofrequency signals in the X‐ and Ku‐bands. Lenses produced with more distinct low‐loss materials (up to 5) can deliver an 18 dB signal gain with a
Lawrence Romangsuriat +3 more
wiley +1 more source
Functional connection between Rad51 and PML in homology-directed repair. [PDF]
PLoS ONE, 2011 The promyelocytic leukemia protein (PML) is a tumor suppressor critical for formation of nuclear bodies (NBs) performing important functions in transcription, apoptosis, DNA repair and antiviral responses.
Sergei Boichuk +4 more
doaj +1 more source
UBE1L represses PML/RARα by targeting the PML domain for ISG15ylation [PDF]
Molecular Cancer Therapeutics, 2008 Abstract Acute promyelocytic leukemia (APL) is characterized by expression of promyelocytic leukemia (PML)/retinoic acid (RA) receptor α (RARα) protein and all-trans-RA-mediated clinical remissions. RA treatment can confer PML/RARα degradation, overcoming dominant-negative effects of this oncogenic protein.
Sumit J, Shah +6 more
openaire +2 more sources
Submicron Metasurface Reconfigured Multiband Smart Windows
Advanced Functional Materials, EarlyView.This work presents a submicron metasurface reconfigured multiband thermochromic smart window. By integrating subwavelength nanostructures into a Fabry−Perot resonator configuration, it mitigates conventional trade‐offs to simultaneously deliver high luminous transmittance and robust solar heating and radiative cooling modulation capabilities ...
Guanya Wang +8 more
wiley +1 more source