Results 1 to 10 of about 908,709 (307)
The Material Properties of the Cell Nucleus: A Matter of Scale [PDF]
Chromatin regulatory processes physically take place in the environment of the cell nucleus, which is filled with the chromosomes and a plethora of smaller biomolecules.
Maud Hertzog, Fabian Erdel
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Super-Resolution Localisation of Nuclear PI(4)P and Identification of Its Interacting Proteome
Phosphoinositides are glycerol-based phospholipids, and they play essential roles in cellular signalling, membrane and cytoskeletal dynamics, cell movement, and the modulation of ion channels and transporters.
Veronika Fáberová +3 more
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Background: Nuclear ribonucleoprotein particles play a key role in RNA processing and in the gene expression pathway. Interchromatin granules (GICs) involved in the metabolism of pre-messenger RNA (pre-mRNA) were described in Allium cepa and ...
Lourdes-Teresa Agredano-Moreno +3 more
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Nuclear Phosphoinositides—Versatile Regulators of Genome Functions
The many functions of phosphoinositides in cytosolic signaling were extensively studied; however, their activities in the cell nucleus are much less clear.
Enrique Castano +7 more
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Differences in the localization and morphology of chromosomes in the human nucleus [PDF]
Using fluorescence in situ hybridization we show striking differences in nuclear position, chromosome morphology, and interactions with nuclear substructure for human chromosomes 18 and 19.
Perry, P +14 more
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Heterogeneity of Organization of Subcompartments in DSB Repair Foci
Cells assemble compartments around DNA double-strand breaks (DSBs). The assembly of this compartment is dependent on the phosphorylation of histone H2AX, the binding of MDC1 to phosphorylated H2AX, and the assembly of downstream signaling and repair ...
Natnael G. Abate, Michael J. Hendzel
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Evolution of the nucleus [PDF]
The nucleus represents a major evolutionary transition. As a consequence of separating translation from transcription many new functions arose, which likely contributed to the remarkable success of eukaryotic cells.
Field, Mark C +4 more
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Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. [PDF]
Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at ...
Dzijak, Rastislav +71 more
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Indeterminate thyroid cytology: detecting malignancy using analysis of nuclear images
Background: Thyroid nodules diagnosed as 'atypia of undetermined significan ce/ follicular lesion of undetermined significance' (AUS/FLUS) or 'f ollicular neoplasm/ suspected follicular neoplasm' (FN/SFN), according to Bethesda’s classification ...
Caroline Y Hayashi +11 more
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Yeast nuclear envelope subdomains with distinct abilities to resist membrane expansion [PDF]
Peer ...
Cohen-Fix, Orna +5 more
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