Results 1 to 10 of about 908,709 (307)

The Material Properties of the Cell Nucleus: A Matter of Scale [PDF]

open access: yesCells, 2023
Chromatin regulatory processes physically take place in the environment of the cell nucleus, which is filled with the chromosomes and a plethora of smaller biomolecules.
Maud Hertzog, Fabian Erdel
doaj   +2 more sources

Super-Resolution Localisation of Nuclear PI(4)P and Identification of Its Interacting Proteome

open access: yesCells, 2020
Phosphoinositides are glycerol-based phospholipids, and they play essential roles in cellular signalling, membrane and cytoskeletal dynamics, cell movement, and the modulation of ion channels and transporters.
Veronika Fáberová   +3 more
doaj   +1 more source

Analysis of the extranucleolar ribonucleoprotein particles of Cycas revoluta Thunb. (Cycadaceae) and Ceratozamia mexicana Brongn. (Zamiaceae)

open access: yesBotan‪ical Sciences, 2022
Background: Nuclear ribonucleoprotein particles play a key role in RNA processing and in the gene expression pathway. Interchromatin granules (GICs) involved in the metabolism of pre-messenger RNA (pre-mRNA) were described in Allium cepa and ...
Lourdes-Teresa Agredano-Moreno   +3 more
doaj   +1 more source

Nuclear Phosphoinositides—Versatile Regulators of Genome Functions

open access: yesCells, 2019
The many functions of phosphoinositides in cytosolic signaling were extensively studied; however, their activities in the cell nucleus are much less clear.
Enrique Castano   +7 more
doaj   +1 more source

Differences in the localization and morphology of chromosomes in the human nucleus [PDF]

open access: yes, 1999
Using fluorescence in situ hybridization we show striking differences in nuclear position, chromosome morphology, and interactions with nuclear substructure for human chromosomes 18 and 19.
Perry, P   +14 more
core   +1 more source

Heterogeneity of Organization of Subcompartments in DSB Repair Foci

open access: yesFrontiers in Genetics, 2022
Cells assemble compartments around DNA double-strand breaks (DSBs). The assembly of this compartment is dependent on the phosphorylation of histone H2AX, the binding of MDC1 to phosphorylated H2AX, and the assembly of downstream signaling and repair ...
Natnael G. Abate, Michael J. Hendzel
doaj   +1 more source

Evolution of the nucleus [PDF]

open access: yes, 2014
The nucleus represents a major evolutionary transition. As a consequence of separating translation from transcription many new functions arose, which likely contributed to the remarkable success of eukaryotic cells.
Field, Mark C   +4 more
core   +1 more source

Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. [PDF]

open access: yes, 2013
Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at ...
Dzijak, Rastislav   +71 more
core   +1 more source

Indeterminate thyroid cytology: detecting malignancy using analysis of nuclear images

open access: yesEndocrine Connections, 2021
Background: Thyroid nodules diagnosed as 'atypia of undetermined significan ce/ follicular lesion of undetermined significance' (AUS/FLUS) or 'f ollicular neoplasm/ suspected follicular neoplasm' (FN/SFN), according to Bethesda’s classification ...
Caroline Y Hayashi   +11 more
doaj   +1 more source

Yeast nuclear envelope subdomains with distinct abilities to resist membrane expansion [PDF]

open access: yes, 2006
Peer ...
Cohen-Fix, Orna   +5 more
core   +1 more source

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