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Frontiers in Cell and Developmental Biology, 2023 Introduction: Imaging of human clinical formalin-fixed paraffin-embedded (FFPE) tissue sections provides insights into healthy and diseased states and therefore represents a valuable resource for basic research, as well as for diagnostic and clinical ...
Peter Hoboth +5 more
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Behavior and biocompatibility of rabbit bone marrow mesenchymal stem cells with bacterial cellulose membrane [PDF]
PeerJ, 2018 Background Tissue engineering has been shown to exhibit great potential for the creation of biomaterials capable of developing into functional tissues.
Marcello de Alencar Silva +9 more
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Tailoring Cellular Function: The Contribution of the Nucleus in Mechanotransduction
Frontiers in Bioengineering and Biotechnology, 2021 Cells sense a variety of different mechanochemical stimuli and promptly react to such signals by reshaping their morphology and adapting their structural organization and tensional state.
Fabrizio A. Pennacchio +4 more
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Super-Resolution Localisation of Nuclear PI(4)P and Identification of Its Interacting Proteome
Cells, 2020 Phosphoinositides are glycerol-based phospholipids, and they play essential roles in cellular signalling, membrane and cytoskeletal dynamics, cell movement, and the modulation of ion channels and transporters.
Veronika Fáberová +3 more
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Botanical Sciences, 2022 Background: Nuclear ribonucleoprotein particles play a key role in RNA processing and in the gene expression pathway. Interchromatin granules (GICs) involved in the metabolism of pre-messenger RNA (pre-mRNA) were described in Allium cepa and ...
Lourdes-Teresa Agredano-Moreno +3 more
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Nuclear Phosphoinositides—Versatile Regulators of Genome Functions
Cells, 2019 The many functions of phosphoinositides in cytosolic signaling were extensively studied; however, their activities in the cell nucleus are much less clear.
Enrique Castano +7 more
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Indeterminate thyroid cytology: detecting malignancy using analysis of nuclear images
Endocrine Connections, 2021 Background: Thyroid nodules diagnosed as 'atypia of undetermined significan ce/ follicular lesion of undetermined significance' (AUS/FLUS) or 'f ollicular neoplasm/ suspected follicular neoplasm' (FN/SFN), according to Bethesda’s classification ...
Caroline Y Hayashi +11 more
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Mechanisms governing the accessibility of DNA damage proteins to constitutive heterochromatin
Frontiers in Genetics, 2022 Chromatin is thought to regulate the accessibility of the underlying DNA sequence to machinery that transcribes and repairs the DNA. Heterochromatin is chromatin that maintains a sufficiently high density of DNA packing to be visible by light microscopy ...
Anastasia Roemer +4 more
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Heterogeneity of Organization of Subcompartments in DSB Repair Foci
Frontiers in Genetics, 2022 Cells assemble compartments around DNA double-strand breaks (DSBs). The assembly of this compartment is dependent on the phosphorylation of histone H2AX, the binding of MDC1 to phosphorylated H2AX, and the assembly of downstream signaling and repair ...
Natnael G. Abate, Michael J. Hendzel
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Application of fractal and euclidean methods to differentiate normal and neoplastic thyroid cells
Indian Journal of Medical and Paediatric Oncology, 2020 Context: The differentiated papillary and follicular thyroid neoplasms can be characterized from the notions of fractal and Euclidean geometry to overcome the challenges faced by the pathologist.
Javier Oswaldo Rodriguez +6 more
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