Heterogeneity of Organization of Subcompartments in DSB Repair Foci
Frontiers in Genetics, 2022 Cells assemble compartments around DNA double-strand breaks (DSBs). The assembly of this compartment is dependent on the phosphorylation of histone H2AX, the binding of MDC1 to phosphorylated H2AX, and the assembly of downstream signaling and repair ...
Natnael G. Abate, Michael J. Hendzel
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MODELLING THE INFLUENCE OF NUCLEUS ELASTICITY ON CELL INVASION IN FIBER NETWORKS AND MICROCHANNELS [PDF]
, 2013 Cell migration in highly constrained extracellular matrices is exploited in scaffold-based tissue engineering and is fundamental in a wide variety of physiological and pathological phenomena, among others in cancer invasion and development. Research into
Preziosi, Luigi, Scianna, Marco
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The Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement [PDF]
, 2012 AIR9 is a cytoskeleton-associated protein in Arabidopsis thaliana with roles in cytokinesis and cross wall maturation, and reported homologues in land plants and excavate protists, including trypanosomatids.
Almeida Costa, Cristina +7 more
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Indeterminate thyroid cytology: detecting malignancy using analysis of nuclear images
Endocrine Connections, 2021 Background: Thyroid nodules diagnosed as 'atypia of undetermined significan ce/ follicular lesion of undetermined significance' (AUS/FLUS) or 'f ollicular neoplasm/ suspected follicular neoplasm' (FN/SFN), according to Bethesda’s classification ...
Caroline Y Hayashi +11 more
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FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism [PDF]
, 2019 A major target of insulin signaling is the FoxO family of Forkhead transcription factors, which translocate from the nucleus to the cytoplasm following insulin-stimulated phosphorylation.
Albrechtsen, N. +15 more
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MONONUCLEOTIDES OF THE CELL NUCLEUS [PDF]
The Journal of General Physiology, 1957 1. It has been demonstrated by ion exchange chromatography that the cell nucleus contains mononucleotides of adenine, guanine, cytosine, uracil, together with diphosphopyridine nucleotide, and several uridine diphosphate derivatives; the adenine nucleotides predominating in amount.
V G, ALLFREY, A E, MIRSKY, S, OSAWA
openaire +2 more sources
In Vivo Localization of Fas-Associated Death Domain Protein in the Nucleus and Cytoplasm of Normal Thyroid and Liver Cells [PDF]
, 2009 FADD (Fas-associated death domain) is the main death receptor adaptor molecule that transmits apoptotic signal. Recently, FADD protein was shown to be expressed both in the cytoplasm and nucleus of in vitro cell lines. In contrast to the cytoplasmic FADD,
Chiocchia, Gilles +2 more
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The connections of the inferior colliculus and the organization of the brainstem auditory system in the greater horseshoe bat (Rhinolophus ferrumequinum) [PDF]
, 1981 The connections of the inferior colliculus, the mammalian midbrain auditory center, were determined in the greater horseshoe bat (Rhinolophus ferrumequinum), using the horseradish peroxidase method.
Adams +70 more
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Mechanisms governing the accessibility of DNA damage proteins to constitutive heterochromatin
Frontiers in Genetics, 2022 Chromatin is thought to regulate the accessibility of the underlying DNA sequence to machinery that transcribes and repairs the DNA. Heterochromatin is chromatin that maintains a sufficiently high density of DNA packing to be visible by light microscopy ...
Anastasia Roemer +4 more
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Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol [PDF]
, 2017 © 2017 The Author(s). Toll-like receptors (TLRs) are major players of the innate immune system. Once activated, they trigger a signalling cascade that leads to NF-ΰ B translocation from the cytoplasm to the nucleus. Single cell analysis shows that NF-ΰ
B Calippe +42 more
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