Results 21 to 30 of about 6,341,201 (297)

Focal Adhesion Protein Vinculin Is Required for Proper Meiotic Progression during Mouse Spermatogenesis

open access: yesCells, 2022
The focal adhesion protein Vinculin (VCL) is ascribed to various cytoplasmic functions; however, its nuclear role has so far been ambiguous. We observed that VCL localizes to the nuclei of mouse primary spermatocytes undergoing first meiotic division ...
Jana Petrusová   +7 more
doaj   +1 more source

PIP2-Effector Protein MPRIP Regulates RNA Polymerase II Condensation and Transcription

open access: yesBiomolecules, 2023
The specific post-translational modifications of the C-terminal domain (CTD) of the Rpb1 subunit of RNA polymerase II (RNAPII) correlate with different stages of transcription.
Can Balaban   +5 more
doaj   +1 more source

Cell Nucleus in Context [PDF]

open access: yesCritical Reviews™ in Eukaryotic Gene Expression, 2000
The molecular pathways that participate in regulation of gene expression are being progressively unraveled. Extracellular signals, including the binding of extracellular matrix and soluble molecules to cell membrane receptors, activate specific signal transducers that process information inside the cell leading to alteration in gene expression. Some of
S A, Lelièvre   +2 more
openaire   +2 more sources

Nucleoporin TPR Affects C2C12 Myogenic Differentiation via Regulation of Myh4 Expression

open access: yesCells, 2021
The nuclear pore complex (NPC) has emerged as a hub for the transcriptional regulation of a subset of genes, and this type of regulation plays an important role during differentiation.
Jana Uhlířová   +5 more
doaj   +1 more source

The F-Actin-Binding MPRIP Forms Phase-Separated Condensates and Associates with PI(4,5)P2 and Active RNA Polymerase II in the Cell Nucleus

open access: yesCells, 2021
Here, we provide evidence for the presence of Myosin phosphatase rho-interacting protein (MPRIP), an F-actin-binding protein, in the cell nucleus. The MPRIP protein binds to Phosphatidylinositol 4,5-bisphosphate (PIP2) and localizes to the nuclear ...
Can Balaban   +3 more
doaj   +1 more source

Limited Proteolysis-Coupled Mass Spectrometry Identifies Phosphatidylinositol 4,5-Bisphosphate Effectors in Human Nuclear Proteome

open access: yesCells, 2021
Specific nuclear sub-compartments that are regions of fundamental processes such as gene expression or DNA repair, contain phosphoinositides (PIPs). PIPs thus potentially represent signals for the localization of specific proteins into different nuclear ...
Martin Sztacho   +5 more
doaj   +1 more source

MONONUCLEOTIDES OF THE CELL NUCLEUS [PDF]

open access: yesThe Journal of General Physiology, 1957
1. It has been demonstrated by ion exchange chromatography that the cell nucleus contains mononucleotides of adenine, guanine, cytosine, uracil, together with diphosphopyridine nucleotide, and several uridine diphosphate derivatives; the adenine nucleotides predominating in amount.
V G, ALLFREY, A E, MIRSKY, S, OSAWA
openaire   +2 more sources

Lipid Microdomains in Cell Nucleus [PDF]

open access: yesMolecular Biology of the Cell, 2008
It is known that nuclear lipids play a role in proliferation, differentiation, and apoptotic process. Cellular nuclei contain high levels of phosphatidylcholine and sphingomyelin, which are partially linked with cholesterol and proteins to form lipid–protein complexes.
Cascianelli, Giacomo   +6 more
openaire   +3 more sources

The distribution of N-acetylgalactosamine in the cochlear nucleus of the gerbil revealed by lectin binding with soybean agglutinin [PDF]

open access: yes, 1994
A horseradish peroxidase conjugated lectin from Glycine max (soy bean agglutinin; SBA) was used to characterise the distribution of N-acetylgalactosamine in the cochlear nucleus of the mongolian gerbil. SBA bound differentially to a variety of structures
Gleich, Otto, Otto Gleich
core   +1 more source

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