Results 11 to 20 of about 5,980,419 (302)
The Material Properties of the Cell Nucleus: A Matter of Scale [PDF]
Chromatin regulatory processes physically take place in the environment of the cell nucleus, which is filled with the chromosomes and a plethora of smaller biomolecules.
Maud Hertzog, Fabian Erdel
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Mitochondrial Factors in the Cell Nucleus. [PDF]
The origin of eukaryotic organisms involved the integration of mitochondria into the ancestor cell, with a massive gene transfer from the original proteobacterium to the host nucleus. Thus, mitochondrial performance relies on a mosaic of nuclear gene products from a variety of genomes.
González-Arzola K, Díaz-Quintana A.
europepmc +6 more sources
Lamin A/C and PI(4,5)P2—A Novel Complex in the Cell Nucleus [PDF]
Lamins, the nuclear intermediate filaments, are important regulators of nuclear structural integrity as well as nuclear functional processes such as DNA transcription, replication and repair, and epigenetic regulations.
Sara Escudeiro-Lopes +3 more
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Physical Training Chronically Stimulates the Motor Neuron Cell Nucleus in the Ts65Dn Mouse, a Model of Down Syndrome [PDF]
Down syndrome (DS) is a genetically-based disease based on the trisomy of chromosome 21 (Hsa21). DS is characterized by intellectual disability in association with several pathological traits among which early aging and altered motor coordination are ...
Chiara Rita Inguscio +4 more
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Genome-Directed Cell Nucleus Assembly [PDF]
The cell nucleus is frequently considered a cage in which the genome is placed to protect it from various external factors. Inside the nucleus, many functional compartments have been identified that are directly or indirectly involved in implementing ...
Sergey V. Razin, Sergey V. Ulianov
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Mechanobiology of the cell nucleus. [PDF]
Lammerding J, Engler AJ, Kamm R.
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Differences in the localization and morphology of chromosomes in the human nucleus [PDF]
Using fluorescence in situ hybridization we show striking differences in nuclear position, chromosome morphology, and interactions with nuclear substructure for human chromosomes 18 and 19.
Perry, P +5 more
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Mitochondrial TFAM as a Signaling Regulator between Cellular Organelles: A Perspective on Metabolic Diseases [PDF]
Tissues actively involved in energy metabolism are more likely to face metabolic challenges from bioenergetic substrates and are susceptible to mitochondrial dysfunction, leading to metabolic diseases.
Jin-Ho Koh +3 more
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The focal adhesion protein Vinculin (VCL) is ascribed to various cytoplasmic functions; however, its nuclear role has so far been ambiguous. We observed that VCL localizes to the nuclei of mouse primary spermatocytes undergoing first meiotic division ...
Jana Petrusová +7 more
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PIP2-Effector Protein MPRIP Regulates RNA Polymerase II Condensation and Transcription
The specific post-translational modifications of the C-terminal domain (CTD) of the Rpb1 subunit of RNA polymerase II (RNAPII) correlate with different stages of transcription.
Can Balaban +5 more
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