Results 11 to 20 of about 908,709 (307)
Mechanobiology of the cell nucleus [PDF]
APL Bioengineering, 2022 Jan Lammerding +2 more
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Mitochondrial Factors in the Cell Nucleus [PDF]
International Journal of Molecular Sciences, 2023 The origin of eukaryotic organisms involved the integration of mitochondria into the ancestor cell, with a massive gene transfer from the original proteobacterium to the host nucleus. Thus, mitochondrial performance relies on a mosaic of nuclear gene products from a variety of genomes.
Katiuska González-Arzola +1 more
openaire +6 more sources
Cell Stem Cell, 2017 Stem cell engineering and grafting of mesencephalic dopamine (mesDA) neurons is a promising strategy for brain repair in Parkinson's disease (PD). Refinement of differentiation protocols to optimize this approach will require deeper understanding of ...
Nigel Kee +2 more
exaly +3 more sources
Lamin A/C and PI(4,5)P2—A Novel Complex in the Cell Nucleus [PDF]
CellsLamins, the nuclear intermediate filaments, are important regulators of nuclear structural integrity as well as nuclear functional processes such as DNA transcription, replication and repair, and epigenetic regulations.
Sara Escudeiro-Lopes +3 more
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Physical Training Chronically Stimulates the Motor Neuron Cell Nucleus in the Ts65Dn Mouse, a Model of Down Syndrome [PDF]
Cells, 2023 Down syndrome (DS) is a genetically-based disease based on the trisomy of chromosome 21 (Hsa21). DS is characterized by intellectual disability in association with several pathological traits among which early aging and altered motor coordination are ...
Chiara Rita Inguscio +4 more
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Genome-Directed Cell Nucleus Assembly [PDF]
Biology, 2022 The cell nucleus is frequently considered a cage in which the genome is placed to protect it from various external factors. Inside the nucleus, many functional compartments have been identified that are directly or indirectly involved in implementing ...
Sergey V. Razin, Sergey V. Ulianov
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The role of the cell nucleus in mechanotransduction
Current Opinion in Cell Biology, 2020 © 2020 Elsevier Ltd. All rights reserved.Mechanical forces are known to influence cellular processes with consequences at the cellular and physiological level.
Gomes, Edgar +2 more
core +4 more sources
Mitochondrial TFAM as a Signaling Regulator between Cellular Organelles: A Perspective on Metabolic Diseases [PDF]
Diabetes & Metabolism Journal, 2021 Tissues actively involved in energy metabolism are more likely to face metabolic challenges from bioenergetic substrates and are susceptible to mitochondrial dysfunction, leading to metabolic diseases.
Jin-Ho Koh +3 more
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Cells, 2022 The focal adhesion protein Vinculin (VCL) is ascribed to various cytoplasmic functions; however, its nuclear role has so far been ambiguous. We observed that VCL localizes to the nuclei of mouse primary spermatocytes undergoing first meiotic division ...
Jana Petrusová +7 more
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PIP2-Effector Protein MPRIP Regulates RNA Polymerase II Condensation and Transcription
Biomolecules, 2023 The specific post-translational modifications of the C-terminal domain (CTD) of the Rpb1 subunit of RNA polymerase II (RNAPII) correlate with different stages of transcription.
Can Balaban +5 more
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