Results 61 to 70 of about 46,902 (263)
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Preparation of LaB6 Powders via Calciothermic Reduction using Mechanochemistry and Acid Leaching
KONA Powder and Particle Journal, 2015 This study reports a room temperature mechanochemical route for the synthesis of LaB6 powders originated from related metal oxide powders as La2O3 and B2O3.
Duygu Ağaoğulları +3 more
doaj +1 more source
Requirement of PML SUMO interacting motif for RNF4- or arsenic trioxide-induced degradation of nuclear PML isoforms. [PDF]
PLoS ONE, 2012 PML, the organizer of nuclear bodies (NBs), is expressed in several isoforms designated PMLI to VII which differ in their C-terminal region due to alternative splicing of a single gene.
Mohamed Ali Maroui +5 more
doaj +1 more source
Advanced Engineering Materials, Volume 27, Issue 6, March 2025.ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
PLoS ONE, 2011 The PML tumor suppressor is the founding component of the multiprotein nuclear structures known as PML nuclear bodies (PML-NBs), which control several cellular functions including apoptosis and antiviral effects.
Feroz Sarkari +3 more
doaj +1 more source
UBE1L represses PML/RARα by targeting the PML domain for ISG15ylation [PDF]
Molecular Cancer Therapeutics, 2008 Abstract Acute promyelocytic leukemia (APL) is characterized by expression of promyelocytic leukemia (PML)/retinoic acid (RA) receptor α (RARα) protein and all-trans-RA-mediated clinical remissions. RA treatment can confer PML/RARα degradation, overcoming dominant-negative effects of this oncogenic protein.
Sumit J, Shah +6 more
openaire +2 more sources
Symmetry‐Guided Multifunctional Acoustic System Based on Mechanically Actuated Sonic Crystals
Advanced Engineering Materials, EarlyView.This study presents the design, simulation, and experimental validation of amultifunctional acoustic metamaterial based on rotationally engineered sonic crystals.By tuning cylinder orientations, controllable band gaps and six distinct functionalities—including switching, topological insulation, beam splitting, and logic operations—areachieved ...
Yuanyan Zhao +2 more
wiley +1 more source
Crosstalk between p53 modifiers at PML bodies
Molecular & Cellular Oncology, 2018 Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage.
Sonja Matt, Thomas G Hofmann
doaj +1 more source
A Role for PML in Innate Immunity [PDF]
Genes & Cancer, 2011 The promyelocytic leukemia gene (PML) of acute promyelocytic leukemia is an established tumor suppressor gene with critical functions in growth suppression, induction of apoptosis, and cellular senescence. Interestingly, although less studied, PML seems to play a key role also in immune response to viral infection.
Lunardi A +15 more
openaire +8 more sources