NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li +7 more
wiley +1 more source
Association Between Inflammatory Cytokines (IL-6 and IL-10) and Trauma Severity: Correlations With Shock Index and ABC Score in Trauma Patients-A Prospective Observational Study. [PDF]
de Oliveira RG +5 more
europepmc +1 more source
We report photostable, photoluminescent deep eutectic solvents (DESs) powered by in situ‐formed zero‐dimensional (0D) halometallates. Stabilized by microenvironment‐controlling hydrogen bond acceptor (HBA) and donor (HBD) networks, these DESs exhibit vibrant, metal ion‐tunable emission (PLQY = 60.2%).
Jeesu Moon +4 more
wiley +1 more source
Autism Spectrum Disorder and Cardiovascular Risk: The Role of Frontal QRS-T Angle and Systemic Immune-Inflammation Index. [PDF]
Balatacı U, Ay B.
europepmc +1 more source
This study evaluates the applicability and reliability of the ABC method as an indicator of the level of organic pollution in non-vegetated tidal flats in a subtropical estuary in southern Brazil.
Brauko, Kalina Manabe +2 more
core
FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model
FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble +9 more
wiley +1 more source
Antiretroviral therapy persistence among treatment-experienced people with HIV and mental health disorders and/or substance use disorders in the USA (2017-2024): a retrospective cohort study. [PDF]
Mordi U +7 more
europepmc +1 more source
From Defense Executor to Engineering Target: Harnessing Lignin for Crop Resistance
Lignin serves as both a physical and chemical executor of broad‐spectrum plant immunity. This review systematically summarizes classical and recent advances in lignin‐mediated immunity, outlines the multifaceted regulatory modules controlling lignification under biotic stress, discusses key physiological and biochemical mechanisms behind lignin‐based ...
Yanwen Yu +6 more
wiley +1 more source
Reliability and validity of the balance recovery confidence scale in persons with stroke. [PDF]
Wangthomrong L +6 more
europepmc +1 more source
A multimodal tactile sensor module that mimics the spatial arrangement and function of Merkel discs and Meissner corpuscles within the human papillary structure operates in a self‐powered manner, responding to both dynamic and static stimuli, achieving tactile perception more similar to human skin.
Jaehyeong Kim +4 more
wiley +1 more source

