Results 61 to 70 of about 4,295,538 (284)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
On Topological Indices of Certain Families of Nanostar Dendrimers
Molecules, 2016 A topological index of graph G is a numerical parameter related to G which characterizes its molecular topology and is usually graph invariant. In the field of quantitative structure-activity (QSAR)/quantitative structure-activity structure-property ...
Mohamad Nazri Husin +3 more
doaj +1 more source
On Topological Indices for New Classes of Benes Network
Journal of Mathematics, 2021 Topological indices (TIs) transform a molecular graph into a number. The TIs are a vital tool for quantitative structure activity relationship (QSAR) and quantity structure property relationship (QSPR).
Aftab Hussain +5 more
doaj +1 more source
Assessment Level of Severity of Environmental Disturbance Caused by Aquaculture Activities Using Abundance-Biomass Curves of Macrobenthic Assemblages [PDF]
, 2015 Abundance-Biomass comparison (ABC) was applied to assess the level of environmental disturbance by the changes in the pattern of abundance and biomass of macrobenthic assemblages taken from various types of sediments. In the most sedimentary habitats,
Putro, Sapto P. +2 more
core
The (ABC) Conjecture and the radical index of integers [PDF]
Acta Arithmetica, 2001 The author introduces a new definition: the \textit{radical index} \(\nu(n)\) of an integer \(n\) with \(|n|>1\) which is given by the formula \(|\text{rad} (n)|^{\nu(n)}=|n|\) where, as usual, \(\text{rad} (n)=\prod_{p \mid n}p\). Then this concept is used in relation to the \((ABC)\) conjecture.
openaire +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Frontiers in Cardiovascular Medicine, 2022 ObjectiveTo evaluate performance of the ABC (Age, Biomarkers, Clinical history)-bleeding risk score in estimating major bleeding risk in Chinese patients with atrial fibrillation (AF) on oral anticoagulation (OAC) therapy in real-world practice ...
Yu-Feng Wang +12 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
ARO-The Scientific Journal of Koya University, 2018 Researchers, widely have introduced the Artificial Bee Colony (ABC) as an optimization algorithm to deal with classification, and prediction problems.
Tarik A. Rashid, Saman M. Abdullah
doaj +1 more source