Results 91 to 100 of about 6,585 (184)
Journal of Arrhythmia, Volume 41, Issue 6, December 2025.Mendelian randomization analyses suggest that genetic proxies for antidiabetic drug targets—KCNJ11/ABCC8, SLC5A2, and RXRB—reduce the risk of paroxysmal tachycardia (PT), right bundle branch block (RBBB), and atrial fibrillation (AF), respectively.
Zheng‐Qi Song +7 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
FEBS Letters, Volume 599, Issue 21, Page 3124-3149, November 2025.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Regional association and LD plots of SLC6A20, RORA, and ABCC9 SNPs for HSCR.
, 2014 Associations of SNPs across approximately (A) a 400 kb region around SLC6A20 on chromosome 3p21.3, (B) a 1,065 kb region around RORA on chromosome 15q22.2, and (C) a 500 kb region around ABCC9 on chromosome 12p12.1, under analysis adjusted by RET ...
Joon Seol Bae (223723) +12 more
core +1 more source
Identifying pathways modulating sleep duration: from genomics to transcriptomics
Scientific Reports, 2017 Recognizing that insights into the modulation of sleep duration can emerge by exploring the functional relationships among genes, we used this strategy to explore the genome-wide association results for this trait.
Karla V. Allebrandt +10 more
doaj +1 more source
A Case Report of Cantu Syndrome Highlighting the Importance of Genetic Sequencing in Addition to Radiological Testing [PDF]
Journal of Clinical and Diagnostic ResearchAn infant initially suspected to have glutaric aciduria was later diagnosed with Cantu syndrome and found to be a carrier of Congenital Disorder of Glycosylation Type 1j.
Sriranjani Srinivasan +3 more
doaj +1 more source
Heliyon, 2018 ATP-sensitive potassium channels found in both the sarcolemma (sarcKATP) and mitochondria (mitoKATP) of cardiomyocytes are important mediators of cardioprotection during ischemic heart disease.
Mohun Ramratnam +7 more
doaj +1 more source
Isolation and Cloning of ABCC9 Gene from Rasbora sarawakensis [PDF]
, 2015 ATP Binding Cassette subfamily C member 9 (ABCC9) gene plays important role of producing the receptor of sulfonylurea 2 (SUR2). The organism used for this research is Rasbora sarawakensis which is used as vertebrate model for biomedical research.
Aimi Wahidah, Aminan
core
KATP channel subunits are expressed in the epididymal epithelium in several mammalian species.
, 2008 Adenosine triphosphate-sensitive K(++) (K(ATP)) channels are poorly characterized in the reproductive tract. The present study was designed to evaluate the putative expression of K(ATP) channel subunits (Kir6.x and SURx) in the epididymis from different ...
Petein, Michel +5 more
core +1 more source
JCI InsightCantú syndrome is a multisystem disorder caused by gain-of-function (GOF) mutations in KCNJ8 and ABCC9, the genes encoding the pore-forming inward rectifier Kir6.1 and regulatory sulfonylurea receptor SUR2B subunits, respectively, of vascular ATP ...
Elsayed Metwally +10 more
doaj +1 more source