Results 31 to 40 of about 5,533 (163)

TEG®6s system measures the contributions of both platelet count and platelet function to clot formation at the site-of-care

open access: yesPlatelets, 2020
Knowledge of platelet count and function is key to ensuring appropriate hemostatic management. We hypothesized that the novel, portable TEG®6s coagulation assessment system could evaluate the contribution of both platelet count and function to clot ...
Joao D. Dias   +5 more
doaj   +1 more source

Comprehensive Multi‐Omics Analysis Reveals NPC2 and ITGAV Genes as Potential Prognostic Biomarkers in Gastrointestinal Cancers

open access: yesCancer Reports, Volume 7, Issue 12, December 2024.
ABSTRACT Background Gastrointestinal cancers (GICs) continue to dominate in terms of both incidence and mortality worldwide. Due to the absence of efficient and accurate prognostic biomarkers, the prognosis and treatment outcomes of many GICs are poor. Identifying biomarkers to predict individual clinical outcomes efficiently is a fundamental challenge
Moein Piroozkhah   +3 more
wiley   +1 more source

Anoikis in cell fate, physiopathology, and therapeutic interventions

open access: yesMedComm, Volume 5, Issue 10, October 2024.
1. Anoikis is an integrin‐dependent form of apoptosis and can affect cell fate. 2. Anoikis widely exists in the physiological and pathological processes of life. 3. Anoikis‐based regulatory strategies are potential targets for therapeutic intervention.
Jie Mei   +12 more
wiley   +1 more source

Abciximab: a reappraisal of its use in coronary care

open access: yesBiologics: Targets & Therapy, 2008
Marco Valgimigli, Gianluca Campo, Matteo Tebaldi, Roberto Carletti, Chiara Arcozzi, Roberto Ferrari, Gianfranco PercocoCardiovascular Institute, Azienda Ospedaliera Universitaria S.
Marco Valgimigli   +5 more
doaj  

Mechanism of Bile Acid in Regulating Platelet Function and Thrombotic Diseases

open access: yesAdvanced Science, Volume 11, Issue 32, August 27, 2024.
Bile acids play critical roles in platelet activation via Syk, PLCγ2, PI3K, Akt, and ERK1/2 pathway, which is also associated with Syntaxin‐11 and NCK1. Additional Bile acids (LCA) supplementation attenuated atherosclerotic plaque development and reduce the inflammation in mice.
Xianghui Zhou   +9 more
wiley   +1 more source

Abciximab in the management of acute myocardial infarction with ST-segment elevation: evidence-based treatment, current clinical use, and future perspectives

open access: yesTherapeutics and Clinical Risk Management, 2014
Artur Dziewierz,1 Tomasz Rakowski,1 Dariusz Dudek2 12nd Department of Cardiology, Jagiellonian University Medical College, Krakow, Poland; 2Department of Interventional Cardiology, Jagiellonian University Medical College, Krakow, Poland Abstract ...
Dziewierz A, Rakowski T, Dudek D
doaj  

Trombose de seio dural: relato de caso Dural sinus thrombosis: case report

open access: yesArquivos de Neuro-Psiquiatria, 2006
Relata-se o caso de uma gestante de 24 anos, encaminhada ao serviço de neurologia por apresentar agitação, alucinações, confusão mental, cefaléia, perda de visão, afasia e convulsões.
Asdrubal Falavigna   +2 more
doaj   +1 more source

Platelet glycoprotein IIb/IIIa antagonists in ischemic stroke patients without endovascular therapy: A meta‐analysis

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 44, Issue 8, Page 675-691, August 2024.
Abstract Platelet glycoprotein (GP) IIb/IIIa antagonists have been employed in selective patients after endovascular therapy (EVT) for acute ischemic stroke (AIS), yet application in patients without EVT is debated. This meta‐analysis of randomized controlled studies on AIS patients without EVT assessed the effectiveness and safety of platelet GP IIb ...
Dongjun Xu   +7 more
wiley   +1 more source

Safety and efficacy of abciximab as an adjunct to percutaneous coronary intervention

open access: yesVascular Health and Risk Management, 2010
Jennifer Vergara-Jimenez, Pierluigi TricociDepartment of Medicine-Cardiology, Duke Clinical Research Institute, Durham, North Carolina, USAAbstract: Abciximab is a widely studied glycoprotein IIb/IIIa inhibitor, specifically in the setting of patients ...
Jennifer Vergara-Jimenez   +1 more
doaj  

Integrating Computational and Biological Hemodynamic Approaches to Improve Modeling of Atherosclerotic Arteries

open access: yesAdvanced Science, Volume 11, Issue 26, July 10, 2024.
This review describes and critically evaluates computational and biological models of atherosclerosis, focusing on the hemodynamics of occluded coronary arteries. It examines emerging strategies that integrate computational and biological models and explores the advances in imaging, biofabrication, single‐cell omics, and machine learning for model ...
Thao Nhu Anne Marie Vuong   +8 more
wiley   +1 more source

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