Results 81 to 90 of about 14,877 (300)

Abciximab in the treatment of coronary artery disease

open access: yesReviews in Health Care, 2013
Antiplatelet therapy constitutes a cornerstone in the strategies aimed at the effective management of acute coronary syndrome. Abciximab is the oldest and most commonly used intravenous antiplatelet agent in this context, in particular when an invasive strategy is adopted. It is very commonly used in more unstable and high- risk patients.
Jayasinghe, Rohan   +2 more
openaire   +4 more sources

Integrating Computational and Biological Hemodynamic Approaches to Improve Modeling of Atherosclerotic Arteries

open access: yesAdvanced Science, Volume 11, Issue 26, July 10, 2024.
This review describes and critically evaluates computational and biological models of atherosclerosis, focusing on the hemodynamics of occluded coronary arteries. It examines emerging strategies that integrate computational and biological models and explores the advances in imaging, biofabrication, single‐cell omics, and machine learning for model ...
Thao Nhu Anne Marie Vuong   +8 more
wiley   +1 more source

Comparison between Intracoronary Abciximab and Intravenous Eptifibatide Administration during Primary Percutaneous Coronary Intervention of Acute ST-Segment Elevation Myocardial Infarction

open access: yesJournal of Tehran University Heart Center, 2015
Background: Administration of glycoprotein IIb/IIIa inhibitors is an effective adjunctive treatment strategy during primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI).
MohammadHasan Namazi   +5 more
doaj  

Prophylaxis of Experimental Endocarditis With Antiplatelet and Antithrombin Agents: A Role for Long-term Prevention of Infective Endocarditis in Humans? [PDF]

open access: yes, 2017
Background. Infective endocarditis (IE) mostly occurs after spontaneous low-grade bacteremia. Thus, IE cannot be prevented by circumstantial antibiotic prophylaxis.
Chaouch, Aziz   +7 more
core  

Primary Angioplasty in Women: Data from the Portuguese Registry of Interventional Cardiology [PDF]

open access: yes, 2014
Objetivos: A mortalidade na mulher após angioplastia primária (ICP-P) é superior à do homem. Contudo, permanece contraditório o papel do sexo poder ser fator de risco independente para mortalidade no contexto de enfarte agudo do miocárdio com ...
Calé, R   +4 more
core   +1 more source

Small molecule– and peptide–drug conjugates addressing integrins: A story of targeted cancer treatment

open access: yesJournal of Peptide Science, Volume 30, Issue 7, July 2024.
The development of highly affine, selective peptides and small molecules in recent years has allowed peptide drugs (PDCs) and small molecule–drug conjugates (SMDCs) to increasingly compete with antibody–drug conjugates (ADCs). This review summarises and describes integrin‐addressing PDCs and SMDCs, while highlighting points of great interest.
Jannik Paulus, Norbert Sewald
wiley   +1 more source

Investigation of interaction of human platelet membrane components with anticoagulant drugs Abciximab and Eptifibatide

open access: yesFolia Histochemica et Cytobiologica, 2010
Abciximab (Abci) and eptifibatide (Epti) are antiaggregate drugs which may reduce thrombotic complications inacute coronary syndromes. The aim of this work was the investigation of the interaction between the phospholipid-GPIIb/IIIa glycoprotein complex ...
Ewa Gorodkiewicz   +2 more
doaj  

Biosensing materials for monoclonal antibody detection: An overview

open access: yesResponsive Materials, Volume 2, Issue 2, May 2024.
This article provides an overview of the recent advances and functional applications of biosensing materials for monoclonal antibody (mAb) detection. In the review, we present the approaches by which mAb receptors are combined with materials to construct responsive analytical platforms, enabling real‐time monitoring and diagnosis.
Yuxin Zhang   +3 more
wiley   +1 more source

Gli antagonisti del recettore GPIIb/IIIa: farmacologia, clinica ed economia nelle sindromi coronariche acute NSTEMI e nelle rivascolarizzazioni per via percutanea

open access: yesFarmeconomia: Health Economics and Therapeutic Pathways, 2005
Inhibition of platelet glycoprotein IIb/IIIa (GP IIb/IIIa) receptor prevents platelet aggregation by controlling its final common pathway, the cross-binding of fibrinogen, bridging across adjacent platelets.
Lorenzo Pradelli
doaj   +1 more source

Angiographic findings in patients with refractory unstable angina according to troponin T status [PDF]

open access: yes, 1999
BACKGROUND: The CAPTURE (C7E3 fab AntiPlatelet Therapy in Unstable REfactory angina) trial enrolled patients with refractory unstable angina and documented a therapeutic benefit for abciximab, a platelet glycoprotein IIb/IIIa receptor ...
Brand, M.J.B.M. (Marcel) van den   +3 more
core  

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