Background Although percutaneous coronary intervention (PCI) is becoming the standard therapy in ST-segment elevation myocardial infarction (STEMI), to date most patients, even in developed countries, are reperfused with intravenous thrombolysis or do ...
Visser Cees A +5 more
doaj +1 more source
PSAgraphics: An R Package to Support Propensity Score Analysis [PDF]
Propensity score analysis is a technique for adjusting for selection bias in observational data. Estimated propensity scores (probability of treatment given observed covariates) are used for stratification of observations. Within strata covariates should
James E. Helmreich, Robert M. Pruzek
core +1 more source
Angiographic findings in patients with refractory unstable angina according to troponin T status [PDF]
BACKGROUND: The CAPTURE (C7E3 fab AntiPlatelet Therapy in Unstable REfactory angina) trial enrolled patients with refractory unstable angina and documented a therapeutic benefit for abciximab, a platelet glycoprotein IIb/IIIa receptor ...
Brand, M.J.B.M. (Marcel) van den +3 more
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FbsA, a fibrinogen-binding protein from Streptococcus agalactiae, mediates platelet aggregation [PDF]
The bacterium Streptococcus agalactiae is an etiologic agent in the pathogenesis of endocarditis in humans. FbsA, a fibrinogen-binding protein produced by this pathogen, is considered an important virulence factor.
Fitzgerald, J Ross +7 more
core +1 more source
The development of highly affine, selective peptides and small molecules in recent years has allowed peptide drugs (PDCs) and small molecule–drug conjugates (SMDCs) to increasingly compete with antibody–drug conjugates (ADCs). This review summarises and describes integrin‐addressing PDCs and SMDCs, while highlighting points of great interest.
Jannik Paulus, Norbert Sewald
wiley +1 more source
Abciximab (Abci) and eptifibatide (Epti) are antiaggregate drugs which may reduce thrombotic complications inacute coronary syndromes. The aim of this work was the investigation of the interaction between the phospholipid-GPIIb/IIIa glycoprotein complex ...
Ewa Gorodkiewicz +2 more
doaj
Prophylaxis of Experimental Endocarditis With Antiplatelet and Antithrombin Agents: A Role for Long-term Prevention of Infective Endocarditis in Humans? [PDF]
Background. Infective endocarditis (IE) mostly occurs after spontaneous low-grade bacteremia. Thus, IE cannot be prevented by circumstantial antibiotic prophylaxis.
Chaouch, Aziz +7 more
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High bolus tirofiban vs abciximab in acute STEMI patients undergoing primary PCI - The tamip study
Background: Primary percutaneous coronary intervention (PCI) has been shown to be an effective therapy for patients with acute myocardial infarction (MI). Glycoprotein (GP) IIb/IIIa receptor blockers reduce thrombotic complications in patients undergoing
Mohammed A Balghith
doaj +1 more source
Stent thrombosis following bare-metal stent implantation: success of emergency percutaneous coronary intervention and predictors of adverse outcome [PDF]
Aims To investigate the efficacy and outcome of emergency percutaneous coronary interventions (PCI) in patients with stent thrombosis. Methods and results Between 1995 and 2003, 6058 patients underwent bare-metal stent implantation, of which 95 (1.6 ...
Eberli, Franz R. +10 more
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Thromboembolic Complications During Endovascular Treatment of Ruptured Intracranial Aneurysms - Prevention and Therapy [PDF]
As complicações tromboembólicas são as mais frequentemente reportadas durante a terapêutica endovascular de aneurismas intracranianos com espiras metálicas.
Baptista, T +4 more
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