Results 21 to 30 of about 1,523,724 (311)

Isobavachalcone Activates Antitumor Immunity on Orthotopic Pancreatic Cancer Model: A Screening and Validation

Frontiers in Pharmacology, 2022
Pancreatic cancer is accompanied by poor prognosis and accounts for a significant number of deaths every year. Since Psoralea corylifolia L. (PCL) possesses a broad spectrum of bioactivities, it is commonly used in traditional Chinese medicine. The study
Xuanming Liu, Hongbo Zhang, Jianlin Cao, Yuzhen Zhuo, Jiahui Jin, Qiaoying Gao, Xiangfei Yuan, Lei Yang, Dihua Li, Yan Wang, Yan Wang   +10 more
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Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway

Frontiers in Pharmacology, 2021
Pancreatic fibrosis is a pathological characteristic of chronic pancreatitis (CP) and pancreatic cancer. Chaihu Guizhi Ganjiang Decoction (CGGD) is a traditional Chinese medicine, which is widely used in the clinical treatment of digestive diseases ...
Lihua Cui, Caixia Li, Ye Shang, Dihua Li, Yuzhen Zhuo, Lei Yang, Naiqiang Cui, Yuhong Li, Shukun Zhang   +8 more
doaj   +1 more source

Histone demethylase KDM6B inhibits breast cancer metastasis by regulating Wnt/β‐catenin signaling

FEBS Open Bio, 2021
Tumor metastasis remains a major challenge for patients with breast cancer. Aberrant epigenetic factor lysine‐specific demethylase 6B (KDM6B) has been associated with tumor progression.
Jing Xun, Ruifang Gao, Botao Wang, Yifan Li, Yuan Ma, Jun Guan, Qi Zhang   +6 more
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Identification of a Four-Gene Metabolic Signature to Evaluate the Prognosis of Colon Adenocarcinoma Patients

Frontiers in Public Health, 2022
BackgroundColon adenocarcinoma (COAD) is a highly heterogeneous disease, thus making prognostic predictions uniquely challenging. Metabolic reprogramming is emerging as a novel cancer hallmark that may serve as the basis for more effective prognosis ...
Yang Zheng, Yang Zheng, Rilige Wu, Ximo Wang, Ximo Wang, Ximo Wang, Chengliang Yin   +6 more
doaj   +1 more source

Infective endocarditis with embolic renal infarct presenting as acute abdomen [PDF]

Clinical and Experimental Emergency Medicine, 2021
Infective endocarditis (IE) is a disease that is rare but potentially fatal and challenging to diagnose. A 28-year-old man with sickle cell trait and a history of intravenous drug use presented with abdominal pain and hematuria mimicking a surgical ...
Mustafa Mahmood Eid
doaj   +1 more source

A novel nomogram for adult primary perihilar cholangiocarcinoma and considerations concerning lymph node dissection

Frontiers in Surgery, 2023
ObjectiveTo construct a reliable nomogram available online to predict the postoperative survival of patients with perihilar cholangiocarcinoma.MethodsData from 1808 patients diagnosed with perihilar cholangiocarcinoma between 2004 and 2015 were extracted
Qi Zhang, Qi Zhang, Zehan Liu, Zehan Liu, Shuangqing Liu, Ming Wang, Xinye Li, Jing Xun, Jing Xun, Xiangyu Wang, Qin Yang, Ximo Wang, Dapeng Zhang, Dapeng Zhang   +13 more
doaj   +1 more source

The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury

Frontiers in Immunology, 2021
BackgroundThe ligand-activated transcription factor peroxisome proliferator-activated receptor (PPAR) γ plays crucial roles in diverse biological processes including cellular metabolism, differentiation, development, and immune response.
Chunguang Yan, Chunguang Yan, Chunguang Yan, Jing Chen, Yue Ding, Zetian Zhou, Bingyu Li, Chunmin Deng, Dong Yuan, Qi Zhang, Ximo Wang   +10 more
doaj   +1 more source

IgG immune complex-induced acute lung injury is ameliorated by cAMP via down-regulation of C/EBP- and AP-1-mediated transcriptions

Journal of Inflammation, 2023
Background Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) are life threatening pulmonary diseases, and we are now lack of effective therapeutic methods. Inflammatory responses are essential for initiating ALI/
Chunguang Yan, Jing Chen, Huifang Tang, Chunmin Deng, Qi Zhang, Ximo Wang   +5 more
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The effect of ursodeoxycholic acid on the relative expression of the lipid metabolism genes in mouse cholesterol gallstone models

Lipids in Health and Disease, 2020
Background Many studies indicate that gallstone formation has genetic components. The abnormal expression of lipid-related genes could be the basis for particular forms of cholesterol gallstone disease.
Ning Fan, Ke Meng, Yuqing Zhang, Yong Hu, Donghua Li, Qiaoying Gao, Jianhua Wang, Yanning Li, Shangwei Wu, Yunfeng Cui   +9 more
doaj   +1 more source

Parturient with Acute Abdomen

Indian Journal of Critical Care Medicine, 2022
Management of a parturient with an acute abdomen presents unique challenges. We aim to review the common obstetric and nonobstetric causes for acute abdomen in pregnancy, approach to diagnosis, the role of imaging, and management including the scope and timing of operative intervention.Kundu R, Srinivasan S. Parturient with Acute Abdomen. Indian J Crit
Kundu, Riddhi, Srinivasan, Shrikanth
openaire   +2 more sources