Results 11 to 20 of about 3,123,336 (329)

miR-3065-3p promotes stemness and metastasis by targeting CRLF1 in colorectal cancer

open access: yesJournal of Translational Medicine, 2021
Background Colorectal cancer is one of the most common malignancy in the world. It has been reported that cancer stem cells (CSCs) serve as the primary drivers of tumorigenesis and tumor progression.
Yifan Li   +11 more
doaj   +1 more source

Acute Abdomen and Appendicitis in 1010 Pediatric Patients With COVID-19 or MIS-C: A Multinational Experience from Latin America

open access: yesThe Pediatric Infectious Disease Journal, 2021
Background: To date, there are only sporadic reports of acute abdomen and appendicitis in children with coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C).
A. Yock-Corrales   +15 more
semanticscholar   +1 more source

Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Pancreatic fibrosis is a pathological characteristic of chronic pancreatitis (CP) and pancreatic cancer. Chaihu Guizhi Ganjiang Decoction (CGGD) is a traditional Chinese medicine, which is widely used in the clinical treatment of digestive diseases ...
Lihua Cui   +8 more
doaj   +1 more source

Diagnosis and Analysis of Transabdominal and Intracavitary Ultrasound in Gynecological Acute Abdomen

open access: yesComputational and Mathematical Methods in Medicine, 2021
In order to explore the effective diagnosis method of gynecological acute abdomen, this paper takes hospital gynecological acute abdomen patients as samples and selects gynecological acute abdomen patients admitted to the hospital to be included in this ...
Huali Yang   +5 more
semanticscholar   +1 more source

Histone demethylase KDM6B inhibits breast cancer metastasis by regulating Wnt/β‐catenin signaling

open access: yesFEBS Open Bio, 2021
Tumor metastasis remains a major challenge for patients with breast cancer. Aberrant epigenetic factor lysine‐specific demethylase 6B (KDM6B) has been associated with tumor progression.
Jing Xun   +6 more
doaj   +1 more source

Identification of a Four-Gene Metabolic Signature to Evaluate the Prognosis of Colon Adenocarcinoma Patients

open access: yesFrontiers in Public Health, 2022
BackgroundColon adenocarcinoma (COAD) is a highly heterogeneous disease, thus making prognostic predictions uniquely challenging. Metabolic reprogramming is emerging as a novel cancer hallmark that may serve as the basis for more effective prognosis ...
Yang Zheng   +6 more
doaj   +1 more source

Infective endocarditis with embolic renal infarct presenting as acute abdomen [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2021
Infective endocarditis (IE) is a disease that is rare but potentially fatal and challenging to diagnose. A 28-year-old man with sickle cell trait and a history of intravenous drug use presented with abdominal pain and hematuria mimicking a surgical ...
Mustafa Mahmood Eid
doaj   +1 more source

A novel nomogram for adult primary perihilar cholangiocarcinoma and considerations concerning lymph node dissection

open access: yesFrontiers in Surgery, 2023
ObjectiveTo construct a reliable nomogram available online to predict the postoperative survival of patients with perihilar cholangiocarcinoma.MethodsData from 1808 patients diagnosed with perihilar cholangiocarcinoma between 2004 and 2015 were extracted
Qi Zhang   +13 more
doaj   +1 more source

The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury

open access: yesFrontiers in Immunology, 2021
BackgroundThe ligand-activated transcription factor peroxisome proliferator-activated receptor (PPAR) γ plays crucial roles in diverse biological processes including cellular metabolism, differentiation, development, and immune response.
Chunguang Yan   +10 more
doaj   +1 more source

IgG immune complex-induced acute lung injury is ameliorated by cAMP via down-regulation of C/EBP- and AP-1-mediated transcriptions

open access: yesJournal of Inflammation, 2023
Background Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) are life threatening pulmonary diseases, and we are now lack of effective therapeutic methods. Inflammatory responses are essential for initiating ALI/
Chunguang Yan   +5 more
doaj   +1 more source

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