Results 21 to 30 of about 293,723 (185)

Identification of a Four-Gene Metabolic Signature to Evaluate the Prognosis of Colon Adenocarcinoma Patients

Frontiers in Public Health, 2022
BackgroundColon adenocarcinoma (COAD) is a highly heterogeneous disease, thus making prognostic predictions uniquely challenging. Metabolic reprogramming is emerging as a novel cancer hallmark that may serve as the basis for more effective prognosis ...
Yang Zheng, Yang Zheng, Rilige Wu, Ximo Wang, Ximo Wang, Ximo Wang, Chengliang Yin   +6 more
doaj   +1 more source

Infective endocarditis with embolic renal infarct presenting as acute abdomen [PDF]

Clinical and Experimental Emergency Medicine, 2021
Infective endocarditis (IE) is a disease that is rare but potentially fatal and challenging to diagnose. A 28-year-old man with sickle cell trait and a history of intravenous drug use presented with abdominal pain and hematuria mimicking a surgical ...
Mustafa Mahmood Eid
doaj   +1 more source

Role of contrast enhanced computed tomography abdomen in the evaluation of elderly patients presenting to the emergency with acute abdomen- prospective observational study. [PDF]

Int J Emerg Med
Background India’s elderly population is rapidly growing, with 149 million people aged 60 years and above in 2022, projected to double to 347 million by 2050.
Shankar T, Vempalli N, Sasidharan P, Sireesha K, Ameena S, Paul A, Tejpal P, Lalotra DK, Mahalle AS.   +8 more
europepmc   +2 more sources

A novel nomogram for adult primary perihilar cholangiocarcinoma and considerations concerning lymph node dissection

Frontiers in Surgery, 2023
ObjectiveTo construct a reliable nomogram available online to predict the postoperative survival of patients with perihilar cholangiocarcinoma.MethodsData from 1808 patients diagnosed with perihilar cholangiocarcinoma between 2004 and 2015 were extracted
Qi Zhang, Qi Zhang, Zehan Liu, Zehan Liu, Shuangqing Liu, Ming Wang, Xinye Li, Jing Xun, Jing Xun, Xiangyu Wang, Qin Yang, Ximo Wang, Dapeng Zhang, Dapeng Zhang   +13 more
doaj   +1 more source

The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury

Frontiers in Immunology, 2021
BackgroundThe ligand-activated transcription factor peroxisome proliferator-activated receptor (PPAR) γ plays crucial roles in diverse biological processes including cellular metabolism, differentiation, development, and immune response.
Chunguang Yan, Chunguang Yan, Chunguang Yan, Jing Chen, Yue Ding, Zetian Zhou, Bingyu Li, Chunmin Deng, Dong Yuan, Qi Zhang, Ximo Wang   +10 more
doaj   +1 more source

IgG immune complex-induced acute lung injury is ameliorated by cAMP via down-regulation of C/EBP- and AP-1-mediated transcriptions

Journal of Inflammation, 2023
Background Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) are life threatening pulmonary diseases, and we are now lack of effective therapeutic methods. Inflammatory responses are essential for initiating ALI/
Chunguang Yan, Jing Chen, Huifang Tang, Chunmin Deng, Qi Zhang, Ximo Wang   +5 more
doaj   +1 more source

The effect of ursodeoxycholic acid on the relative expression of the lipid metabolism genes in mouse cholesterol gallstone models

Lipids in Health and Disease, 2020
Background Many studies indicate that gallstone formation has genetic components. The abnormal expression of lipid-related genes could be the basis for particular forms of cholesterol gallstone disease.
Ning Fan, Ke Meng, Yuqing Zhang, Yong Hu, Donghua Li, Qiaoying Gao, Jianhua Wang, Yanning Li, Shangwei Wu, Yunfeng Cui   +9 more
doaj   +1 more source

CD44 is a potential immunotherapeutic target and affects macrophage infiltration leading to poor prognosis

Scientific Reports, 2023
CD44 plays a key role in the communication of CSCs with the microenvironment and the regulation of stem cell properties. UALCAN was used to analyze the expression of CD44 in bladder cancer (BLCA) and normal tissue.
Shuangqing Liu, Zehan Liu, Aichen Shang, Jing Xun, Zongjing Lv, Siying Zhou, Cui Liu, Qi Zhang, Yuming Yang   +8 more
doaj   +1 more source

Analysis of risk factors for intra-cystic hemorrhage in microwave ablation of partially cystic thyroid nodules

Frontiers in Endocrinology, 2023
ObjectiveThe aim of this study is to identify risk factors of intra-cystic hemorrhage in microwave ablation of mixed solid and cystic microwave ablation s, and to design a preoperative nomogram to predict the risk value of intraoperative bleeding with ...
Yao Fu, Yuhui Huang, Yongtai Liu, Yu Song   +3 more
doaj   +1 more source

Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma

BMC Cancer, 2022
Background Sodium selenite (SSE) has been reported to exert anti-tumor effects in several cancer cells. However, the underlying mechanisms in renal cancer are yet to be elucidated.
Xiao Liu, Meng Jiang, Chenggang Pang, Jianning Wang, Lijuan Hu   +4 more
doaj   +1 more source