Results 71 to 80 of about 205,808 (310)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Case Report: Beyond the monophasic myth: relapsing Baló’s concentric sclerosis with residual disability

open access: yesFrontiers in Human Neuroscience
BackgroundBaló’s concentric sclerosis (BCS) is a rare demyelinating disorder with a striking radiological signature. Its potential for relapse and the impact of vascular comorbidities on disease course remains underrecognized.Case presentationA 52-year ...
Weiya Li   +20 more
doaj   +1 more source

Hematometra presenting as an acute abdomen in a 13-year-old postmenarchal girl: a case report [PDF]

open access: yes, 2012
Introduction Most underlying diseases for abdominal pain in children are not dangerous. However some require rapid diagnosis and treatment, such as acute ovarian torsion or appendicitis.
Klimek, Miriam   +7 more
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

An acute abdomen pain

open access: yesBMJ Case Reports, 2009
A 61-year-old retired farmer started experiencing severe pain in his abdomen for the last 2 weeks along with abdominal distension, vomiting and inability to pass flatus or faeces. He was investigated on admission to our casualty and an abdominal x ray revealed classical features of intestinal obstruction (fig 1).
Rakesh, Biswas   +6 more
openaire   +3 more sources

Acute gynecological abdomen in children [PDF]

open access: yes, 2010
Acute abdomen is acutely emerging pathological processes in the abdominal cavity of different etiology and clinical course. Among the reasons causing the acute abdomen in children is the torsion ovarian formations in about 15%.
Livșiț, Irina
core  

Scrub typhus presenting as acute abdomen

open access: yes, 2011
Scrub typhus, a zoonosis, is a systemic febrile illness with diverse clinical manifestations. It may also present with signs and symptoms of acute abdomen.
Anil Kanga   +5 more
core   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Functional connectivity across multi-frequency bands in patients with tension-type headache: a resting-state fMRI retrospective study

open access: yesBMC Medical Imaging
Objectives Tension-type headache (TTH) is the most common nervous system disorder worldwide. This study aimed to examine abnormal network-level brain functional connectivity (FC) alterations in patients with TTH across multi-frequency bands.
Jili Wang   +5 more
doaj   +1 more source

ACUTE ABDOMEN systemic sonographic approach to acute abdomen in emergency department: a case series

open access: yesThe Ultrasound Journal, 2019
Background Acute abdomen is a medical emergency with a wide spectrum of etiologies. Point-of-care ultrasound (POCUS) can help in early identification and management of the causes.
Maryam Al Ali   +2 more
doaj   +1 more source

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