Evidence of Pleiotropic Loci for Fasting Insulin, Total Fat Mass, and Abdominal Visceral Fat in a Sedentary Population: The HERITAGE Family Study [PDF]
AbstractObjective:To examine whether there is a major gene effect on fasting insulin and pleiotropic loci for fasting insulin, total fat mass (FM), and abdominal visceral fat (AVF).Research Methods and Procedures:A major gene hypothesis for fasting plasma insulin levels was assessed using segregation analyses of data on 495 members in 98 normolipidemic
Y, Hong +10 more
openaire +2 more sources
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Objectives: Assess the association between the anthropometric measurements of obesity, body composition with total and regional fat areas determined by CT in obese adolescents.Patients and method: 33 obese adolescents and 20 control group were assessed using anthropometry and body composition.
Abd El-Dayem, Soha M. +4 more
openaire +3 more sources
Short-term effects of glucagon-like peptide 1 (GLP-1) receptor agonists on fat distribution in patients with type 2 diabetes mellitus: an ultrasonography study [PDF]
AIMS:Glucagon-like peptide 1 receptor agonists (GLP-1 RA) induce weight loss and reduction in adipose tissue, but the effects of GLP-1 RA on the distribution of fat deposits have been poorly investigated. METHODS: In 25 patients with type 2 diabetes (16
Carnevale, Vincenzo +9 more
core +1 more source
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad +2 more
wiley +1 more source
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li +7 more
wiley +1 more source
Effects of a home-based exercise program in body composition, abdominal fat and lipid profile in patients with coronary artery disease [PDF]
Coronary artery disease and aging seems to be associated with a sedentary lifestyle, contributing to increased abdominal fat and consequently metabolic complications.
Albuquerque, Aníbal +5 more
core
Design of the sex hormones and physical exercise (SHAPE) study [PDF]
Background Physical activity has been associated with a decreased risk for breast cancer. The biological mechanismn(s) underlying the association between physical activity and breast cancer is not clear.
A McTiernan +62 more
core +3 more sources
Where is the beef? Waist circumference is more highly correlated with BMI and total body fat than with abdominal visceral fat in children [PDF]
Medically accepted ‘facts’ sometimes become outmoded when additional research shows them to be incorrect. This Commentary evaluates the evidence for the measurement of waist circumference (WC) in children and adolescents as a good surrogate for the measurement of abdominal visceral fat (VF) and for assessing the risk for ‘metabolic syndrome’.
P T, Katzmarzyk, C, Bouchard
openaire +2 more sources
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang +7 more
wiley +1 more source

