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In recent decades, obesity has become one of the most common metabolic diseases [...]
Javier Gómez-Ambrosi
doaj +4 more sources
Targeting adipose tissue [PDF]
Two different types of adipose tissues can be found in humans enabling them to respond to starvation and cold: white adipose tissue (WAT) is generally known and stores excess energy in the form of triacylglycerol (TG), insulates against cold, and serves ...
Haas Bodo +3 more
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White Adipose Tissue ............................................................................................................................... 8 Brown Adipose Tissue ...................................................................................
Matthew R. Lindberg, Laura W. Lamps
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IntroductionNon-alcoholic fatty liver disease (NAFLD) can progress to more severe stages, such as steatohepatitis and fibrosis. Thermoneutral housing together with high-fat diet promoted NAFLD progression in C57BL/6J mice.
Olga Horakova +13 more
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Adipose tissue-specific ablation of PGC-1β impairs thermogenesis in brown fat
Impaired thermogenesis observed in mice with whole-body ablation of peroxisome proliferator-activated receptor-γ coactivator-1β (PGC-1β; officially known as PPARGC1B) may result from impaired brown fat (brown adipose tissue; BAT) function, but other ...
Jiří Funda +10 more
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A pyrexic effect of FGF21 independent of energy expenditure and UCP1
Objective: Administration of FGF21 to mice reduces body weight and increases body temperature. The increase in body temperature is generally interpreted as hyperthermia, i.e.
Petr Zouhar +10 more
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Epicardial adipose tissue in contemporary cardiology
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and unobstructed proximity to the heart and has a transcriptome and secretome very ...
G. Iacobellis
semanticscholar +1 more source
Adipose tissue at single-cell resolution.
Adipose tissue exhibits remarkable plasticity with capacity to change in size and cellular composition under physiological and pathophysiological conditions.
Babukrishna Maniyadath +3 more
semanticscholar +1 more source
Adipose tissue macrophages in aging-associated adipose tissue function [PDF]
"Inflammaging" refers to the chronic, low-grade inflammation that characterizes aging. Aging, like obesity, is associated with visceral adiposity and insulin resistance. Adipose tissue macrophages (ATMs) have played a major role in obesity-associated inflammation and insulin resistance. Macrophages are elevated in adipose tissue in aging.
Lu, Bangchao +6 more
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Adipose-tissue plasticity in health and disease.
Adipose tissue, colloquially known as "fat," is an extraordinarily flexible and heterogeneous organ. While historically viewed as a passive site for energy storage, we now appreciate that adipose tissue regulates many aspects of whole-body physiology ...
Alexander Sakers +3 more
semanticscholar +1 more source

