Results 21 to 30 of about 4,824,121 (309)

Adipose tissue macrophages: Regulators of adipose tissue immunometabolism during obesity

Molecular Metabolism, 2022
Background: Adipose tissue macrophages (ATMs) are a well characterized regulator of adipose tissue inflammatory tone. Previously defined by the M1 vs M2 classification, we now have a better understanding of ATM diversity that departs from the old ...
Sierra A. Nance, Lindsey Muir, Carey Lumeng   +2 more
doaj   +1 more source

Extracellular vesicles mediate the communication of adipose tissue with brain and promote cognitive impairment associated with insulin resistance.

Cell Metabolism, 2022
Type 2 diabetes with obesity-related insulin resistance as the main manifestation is associated with an increased risk of cognitive impairment. Adipose tissue plays an important role in this process.
Jin Wang, Liang Li, Zhou Zhang, Xuhong Zhang, Ye-Qian Zhu, Chenyu Zhang, Y. Bi   +6 more
semanticscholar   +1 more source

Omega-3 PUFAs prevent bone impairment and bone marrow adiposity in mouse model of obesity

Communications Biology, 2023
Obesity adversely affects bone and fat metabolism in mice and humans. Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) have been shown to improve glucose metabolism and bone homeostasis in obesity.
Andrea Benova, Michaela Ferencakova, Kristina Bardova, Jiri Funda, Jan Prochazka, Frantisek Spoutil, Tomas Cajka, Martina Dzubanova, Tim Balcaen, Greet Kerckhofs, Wouter Willekens, G. Harry van Lenthe, Arzuv Charyyeva, Glenda Alquicer, Alena Pecinova, Tomas Mracek, Olga Horakova, Roman Coupeau, Morten Svarer Hansen, Martin Rossmeisl, Jan Kopecky, Michaela Tencerova   +21 more
doaj   +1 more source

A Differential Pattern of Batokine Expression in Perivascular Adipose Tissue Depots From Mice

Frontiers in Physiology, 2021
Depending on its anatomical placement, perivascular adipose tissue (PVAT) has been found to possess features more (e.g., aortic thoracic) or less (e.g., aortic abdominal) similar to brown/beige adipose tissue in mice, whereas PVAT surrounding the ...
Alberto Mestres-Arenas, Joan Villarroya, Joan Villarroya, Joan Villarroya, Marta Giralt, Marta Giralt, Marta Giralt, Francesc Villarroya, Francesc Villarroya, Francesc Villarroya, Marion Peyrou, Marion Peyrou, Marion Peyrou   +12 more
doaj   +1 more source

Perivascular Adipose Tissue [PDF]

, 2019
Key Concepts:- While traditionally viewed as little more than a simple lipid reserve, perivascular adipose tissue (PVAT) boasts an extensive biological arsenal which when mobilized can modulate vascular function.- PVAT dysfunction in disease is associated with alteration to its secretory profile which can create a contractile and pro-inflammatory ...
Javed, Saad, Alakrawi, Mariam, Greenstein, Adam S.   +2 more
openaire   +1 more source

Adipose Tissue Inflammation and Metabolic Dysfunction in Obesity.

American Journal of Physiology - Cell Physiology, 2020
Several lines of preclinical and clinical research have confirmed that chronic low-grade inflammation of adipose tissue is mechanistically linked to metabolic disease and organ tissue complications in the overweight and obese organism.
Tatsuo Kawai, M. Autieri, R. Scalia
semanticscholar   +1 more source

Reduced Number of Adipose Lineage and Endothelial Cells in Epididymal fat in Response to Omega-3 PUFA in Mice Fed High-Fat Diet

Marine Drugs, 2018
We found previously that white adipose tissue (WAT) hyperplasia in obese mice was limited by dietary omega-3 polyunsaturated fatty acids (omega-3 PUFA). Here we aimed to characterize the underlying mechanism.
Katerina Adamcova, Olga Horakova, Kristina Bardova, Petra Janovska, Marie Brezinova, Ondrej Kuda, Martin Rossmeisl, Jan Kopecky   +7 more
doaj   +1 more source

Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases

Nutrition and Metabolism, 2022
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining health and homeostasis. Although white adipose tissue and brown adipose tissue are currently considered key endocrine organs, they differ functionally and ...
Sabrina Azevedo Machado, Gabriel Pasquarelli-do-Nascimento, Débora Santos da Silva, G. R. Farias, Igor de Oliveira Santos, Luana Borges Baptista, K. Magalhães   +6 more
semanticscholar   +1 more source

Adipose tissue aging is regulated by an altered immune system

Frontiers in Immunology, 2023
Adipose tissue is a widely distributed organ that plays a critical role in age-related physiological dysfunctions as an important source of chronic sterile low-grade inflammation. Adipose tissue undergoes diverse changes during aging, including fat depot
Yi-Xiang Zhang, Min-Yi Ou, Zi-Han Yang, Yu Sun, Qing-Feng Li, Shuang-Bai Zhou   +5 more
doaj   +1 more source

Physical Exercise-Induced Myokines and Muscle-Adipose Tissue Crosstalk: A Review of Current Knowledge and the Implications for Health and Metabolic Diseases

Frontiers in Physiology, 2018
Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic regimen of regular exercise and pharmaceutical treatment is often recommended for their clinical management.
Luana G. Leal, Luana G. Leal, Magno A. Lopes, Miguel L. Batista, Miguel L. Batista   +4 more
doaj   +1 more source