Results 11 to 20 of about 442,668 (315)

Adipose Tissue Inflammation

Cells, 2023
In recent decades, obesity has become one of the most common metabolic diseases [...]
Javier Gómez-Ambrosi
doaj   +4 more sources

Targeting adipose tissue [PDF]

Diabetology & Metabolic Syndrome, 2012
Two different types of adipose tissues can be found in humans enabling them to respond to starvation and cold: white adipose tissue (WAT) is generally known and stores excess energy in the form of triacylglycerol (TG), insulates against cold, and serves ...
Haas Bodo, Schlinkert Paul, Mayer Peter, Eckstein Niels   +3 more
doaj   +3 more sources

Adipose tissue remodeling: its role in energy metabolism and metabolic disorders

Frontiers in Endocrinology, 2016
The adipose tissue is a central metabolic organ in the regulation of whole-body energy homeostasis. The white adipose tissue (WAT) functions as a key energy reservoir for other organs, whereas the brown adipose tissue (BAT) accumulates lipids for cold ...
Sung Sik eChoe, Jin Young eHuh, In Jae eHwang, Jong In eKim, Jae Bum eKim   +4 more
doaj   +3 more sources

Thermoneutral housing promotes hepatic steatosis in standard diet-fed C57BL/6N mice, with a less pronounced effect on NAFLD progression upon high-fat feeding

Frontiers in Endocrinology, 2023
IntroductionNon-alcoholic fatty liver disease (NAFLD) can progress to more severe stages, such as steatohepatitis and fibrosis. Thermoneutral housing together with high-fat diet promoted NAFLD progression in C57BL/6J mice.
Olga Horakova, Gabriella Sistilli, Gabriella Sistilli, Veronika Kalendova, Veronika Kalendova, Kristina Bardova, Marko Mitrovic, Marko Mitrovic, Tomas Cajka, Ilaria Irodenko, Petra Janovska, Karoline Lackner, Jan Kopecky, Martin Rossmeisl   +13 more
doaj   +1 more source

Adipose tissue-specific ablation of PGC-1β impairs thermogenesis in brown fat

Disease Models & Mechanisms, 2022
Impaired thermogenesis observed in mice with whole-body ablation of peroxisome proliferator-activated receptor-γ coactivator-1β (PGC-1β; officially known as PPARGC1B) may result from impaired brown fat (brown adipose tissue; BAT) function, but other ...
Jiří Funda, Josep A. Villena, Kristina Bardova, Katerina Adamcova, Illaria Irodenko, Pavel Flachs, Ivana Jedlickova, Eliska Haasova, Martin Rossmeisl, Jan Kopecky, Petra Janovska   +10 more
doaj   +1 more source

A pyrexic effect of FGF21 independent of energy expenditure and UCP1

Molecular Metabolism, 2021
Objective: Administration of FGF21 to mice reduces body weight and increases body temperature. The increase in body temperature is generally interpreted as hyperthermia, i.e.
Petr Zouhar, Petra Janovska, Sara Stanic, Kristina Bardova, Jiri Funda, Blanka Haberlova, Birgitte Andersen, Martin Rossmeisl, Barbara Cannon, Jan Kopecky, Jan Nedergaard   +10 more
doaj   +1 more source

Adipose tissue macrophages: their role in adipose tissue remodeling [PDF]

Journal of Leukocyte Biology, 2010
Abstract This review summarizes the role of macrophages in adipose tissue remodeling, particularly focusing on the paracrine loop between adipocytes and macrophages. The adipose tissue secretes a large number of bioactive substances, adipocytokines, which may be involved in a variety of physiologic and pathologic processes.
Takayoshi, Suganami, Yoshihiro, Ogawa
openaire   +2 more sources

Impairment of adrenergically-regulated thermogenesis in brown fat of obesity-resistant mice is compensated by non-shivering thermogenesis in skeletal muscle

Molecular Metabolism, 2023
Objective: Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold or diet, contributing to both thermal and energy homeostasis.
Petra Janovska, Petr Zouhar, Kristina Bardova, Jakub Otahal, Marek Vrbacky, Tomas Mracek, Katerina Adamcova, Lucie Lenkova, Jiri Funda, Tomas Cajka, Zdenek Drahota, Sara Stanic, Arild C. Rustan, Olga Horakova, Josef Houstek, Martin Rossmeisl, Jan Kopecky   +16 more
doaj   +1 more source

Ceramides in Adipose Tissue [PDF]

Frontiers in Endocrinology, 2020
Adipose tissue is a key nutrient-sensing depot that regulates excess energy storage and consumption. Adipocytes, the key components of the adipose tissue, have unique ability to store excess energy in the form of triglycerides, sense systemic energy demands, and secrete factors (lipids, peptides, cytokines, and adipokines) to regulate other metabolic ...
Ying Li, Chad Lamar Talbot, Bhagirath Chaurasia, Bhagirath Chaurasia   +3 more
openaire   +3 more sources

Exercise Training as Therapeutic Approach in Cancer Cachexia: A Review of Potential Anti-inflammatory Effect on Muscle Wasting

Frontiers in Physiology, 2021
Cachexia is a multifactorial inflammatory syndrome with high prevalence in cancer patients. It is characterized by a metabolic chaos culminating in drastic reduction in body weight, mainly due to skeletal muscle and fat depletion. Currently, there is not
Luana G. Leal, Luana G. Leal, Magno A. Lopes, Sidney B. Peres, Miguel L. Batista, Miguel L. Batista   +5 more
doaj   +1 more source