Results 11 to 20 of about 4,824,121 (309)
Update on Adipose Tissue and Cancer.
Endocrine reviews, 2023 Adipose tissue is the largest endocrine organ and an accepted contributor to overall energy homeostasis. There is strong evidence linking increased adiposity to the development of 13 types of cancer.
K. Brown, P. Scherer
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Molecular Metabolism, 2023 Objective: Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold or diet, contributing to both thermal and energy homeostasis.
Petra Janovska +16 more
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Adipose tissue and insulin resistance in obese.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021 Currently, obesity has become a global health issue and is referred to as an epidemic. Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin resistance.
Bulbul Ahmed, R. Sultana, M. Greene
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Frontiers in Physiology, 2021 Cachexia is a multifactorial inflammatory syndrome with high prevalence in cancer patients. It is characterized by a metabolic chaos culminating in drastic reduction in body weight, mainly due to skeletal muscle and fat depletion. Currently, there is not
Luana G. Leal +5 more
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Obesity, Adipose Tissue and Vascular Dysfunction.
Circulation Research, 2021 Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity are strongly associated with comorbidities such as hypertension and insulin resistance, which collectively contribute to the development of cardiovascular diseases ...
M. Koenen, M. Hill, P. Cohen, J. Sowers
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Nature Communications, 2020 Lipid droplets are organelles that regulate lipid metabolism but if organellar contacts play a role during lipolysis is unclear. Here, the authors show that peroxisomes and peroxisomal protein PEX5 play pivotal roles in the spatial and temporal ...
Jinuk Kong +10 more
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Experimental and Molecular Medicine, 2021 Obesity: tracing the inflammation underlying liver disease A deeper understanding of the molecular processes underlying dysfunctional fatty-acid metabolism in nonalcoholic fatty liver disease (NAFLD) could help protect patients from severe liver damage ...
Jin Young Huh, Alan R. Saltiel
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Biomedicines, 2021 Adipose tissue resides in specific depots scattered in peripheral or deeper locations all over the body and it enwraps most of the organs. This tissue is always in a dynamic evolution as it must adapt to the metabolic demand and constraints.
Annie Ladoux +3 more
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Adipocyte, 2021 Mammalian adipose tissue can be divided into two major types, namely, white adipose tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function of WAT is to store excess energy in the form of triglycerides, while BAT is a ...
Long Cheng +13 more
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Adipose tissue aging: mechanisms and therapeutic implications
Cell Death and Disease, 2022 Adipose tissue, which is the crucial energy reservoir and endocrine organ for the maintenance of systemic glucose, lipid, and energy homeostasis, undergoes significant changes during aging.
M. Ou +4 more
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