Results 31 to 40 of about 444,349 (315)

Adipose Tissue as an Endocrine Organ [PDF]

open access: yes, 2018
As one of the largest endocrine organs in the body, adipose tissue secrets a number of bioactive hormones, called adipokines. The expression and secretion of adipokines are tightly controlled and coordinated by physiological and pathophysiological ...
Feng, T, Hui, X
core   +1 more source

Towards clinical translation of upscaled osteogenic grafts using human adipose tissue progenitors [PDF]

open access: yes, 2012
Tissue engineering is an emerging strategy in medical field that focuses on regeneration or replacement of lost or damaged tissue and organs. Most of the tissues in human body have no or limited self renewal and regeneration potential which decrease with
Güven, Sinan
core   +1 more source

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

open access: yesNature Communications, 2017
VLDLR regulates cellular lipoprotein uptake and storage. Here, the authors show that VLDLR, expressed on adipose tissue macrophages, is upregulated in obesity and promotes adipose tissue inflammation by upregulating ceramide production and facilitating ...
Kyung Cheul Shin   +10 more
doaj   +1 more source

LLC tumor cells-derivated factors reduces adipogenesis in co-culture system

open access: yesHeliyon, 2018
Cancer cachexia (CC) is a multifactorial syndrome with an unknown etiology. The primary symptom is the progressive reduction of the body weight. Recently, down-regulation of adipogenic and lipogenic genes were demonstrated to be early affected during ...
Magno Alves Lopes   +4 more
doaj   +1 more source

Leptin, Adiponectin, and Other Adipokines in Regulation of Adipose Tissue Angiogenesis [PDF]

open access: yes, 2013
Adipose tissue plays an important endocrine role through the production of secreted factors, termed adipokines. These include hormones such as leptin, adiponectin, resistin, omentin, apelin, and vaspin; classical cytokines such as tumor necrosis factor-α,
Cao, Y,   +3 more
core   +1 more source

A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences [PDF]

open access: yes, 2010
Depot-dependent differences in adipose tissue physiology may reflect specialized functions and local interactions between adipocytes and surrounding tissues.
Kelder, T.A.J.   +46 more
core   +1 more source

Adipose Angiogenesis Models in Animals and Methodology [PDF]

open access: yes, 2013
Adipose tissue angiogenesis plays a crucial role in the organism as blood vessels are required to supply nutrients and oxygen to the adipose tissue and to remove metabolic waste products.
Honek, J   +5 more
core   +1 more source

SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding

open access: yesNature Communications, 2016
The clock protein Cry regulates hepatic glucose metabolism. Here the authors show that SREBP1c, activated by insulin signalling after feeding, directly regulates Cry transcription at specific circadian time points, and that Cry represses hepatic glucose ...
Hagoon Jang   +11 more
doaj   +1 more source

Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population

open access: yesJournal of Cardiovascular Development and Disease, 2023
The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to ...
Joana Ferreira   +12 more
doaj   +1 more source

The defense of adipose tissue against excess substrate-induced hyperthrophia: Immune system cell infiltration and arrested metabolic activity [PDF]

open access: yes, 2011
Obesity, the excessive accumulation of body fat, is a main defining feature of the metabolic syndrome, and overweight is often an early indication of the future severity and development of associated pathologies.
Alemany, Marià, 1946-, Marià Alemany
core   +1 more source

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