Results 51 to 60 of about 444,349 (315)

The PPARy ligand rosiglitazone influences triacylglycerol metabolism in non-obese males, without increasing the transcriptional activity of PPARy in the subcutaneous adipose tissue [PDF]

, 2008
PPAR¿ is obligatory for fat mass generation and is thought to determine the amount of TAG stored per fat cell. We investigated whether ligand availability for PPAR¿ is rate limiting in fat mass generation and substrate metabolism.
Kersten, A.H., Bakker, A.H.F., Westerterp, K.R., Joosen, A.M.C.P.   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: Prevalence and metabolic consequences [PDF]

, 2010
Lipoatrophy and metabolic complications of treatment of human immunodeficiency virus (HIV) infection may share common associations with adipose tissue pathology and inflammation.
McKinnon, E., Nolan, D., Hammond, E.L.
core   +1 more source

Adipose derived tissue engineered heart valve [PDF]

, 2015
Introduction: A major challenge associated with heart valve tissue engineering is the in vitro creation of mature tissue structures compliant with native valve functionality.
Baaijens, FPT Frank, Beer, G M, Driessen - Mol, A., Hoerstrup, S., Beer, G.M., Baaijens, Frank P T, Baaijens, F.P.T., Weber, B., Hoerstrup, S P, Driessen-Mol, Anita, Frese, Laura, Frese, L., Driessen-Mol, A Anita, Weber, Benedikt, Beer, Gertrude M, Sanders, B Bart, Hoerstrup, S Simon, Sanders, Bart, Sanders, B.   +18 more
core   +1 more source

Faster postnatal decline in hepatic erythropoiesis than granulopoiesis in human newborns

Frontiers in Pediatrics
BackgroundDuring human foetal development, the liver is the primary site of blood cell production, but this activity declines in the third trimester and postnatally as haematopoiesis shifts to bone marrow.
Petra Janovska, Kristina Bardova, Zuzana Prouzova, Zuzana Prouzova, Ilaria Irodenko, Tatyana Kobets, Eliska Haasova, Eliska Haasova, Lenka Steiner Mrazova, Lenka Steiner Mrazova, Viktor Stranecky, Stanislav Kmoch, Martin Rossmeisl, Petr Zouhar, Jan Kopecky   +14 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Estimation of CT-derived abdominal visceral and subcutaneous adipose tissue depots from anthropometry in Europeans, South Asians and African Caribbeans [PDF]

, 2013
Background South Asians and African Caribbeans experience more cardiometabolic disease than Europeans. Risk factors include visceral (VAT) and subcutaneous abdominal (SAT) adipose tissue, which vary with ethnicity and are difficult to quantify using ...
Willis Joseph, Hughes, AD, Ian F. Godsland (212035), Peter Whincup (20840), Peter Whincup, Tillin, T, Therese Tillin, Joseph Willis, Sophie V. Eastwood (459934), Tillin Therese, Andrew Wright (459935), Nita Forouhi (459938), Nita Forouhi, Andrew Wright, Joseph Willis (459937), Eastwood Sophie V., Nishi Chaturvedi, Wright, A, Forouhi, N, Ian F Godsland, Nishi Chaturvedi (130777), Hughes Alun D., Eastwood, SV, Wright Andrew, Chaturvedi, N, Whincup, P, John Heasman (459936), Whincup Peter, Godsland, IF, Chaturvedi Nishi, Sophie V Eastwood, Alun D Hughes, Heasman John, Heasman, J, John Heasman, Forouhi Nita, Willis, J, Alun D. Hughes (395075), Therese Tillin (130770), Godsland Ian F.   +39 more
core   +1 more source

Adipose-Tissue-Specific Expression of Pig ApoR Protects Mice from Diet-Induced Obesity [PDF]

, 2020
Fat deposition is one of the most important economic traits of pigs. Decreasing the subcutaneous fat and increasing the intramuscular fat are believed to be an effective way to improve pork quality, which is one of the main goals of pig breeding ...
Dawei Zhang, Miao Ji, Jin Zhang (53297), Jin Zhang, Ke Xu (134879), Ke Xu, Tingting Chen, Wenjing Wu (457873), Wenjing Wu, Miao Ji (6856586), Tingting Chen (111216), Dawei Zhang (58801), Liangcai Shen, Liangcai Shen (6747938)   +13 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Studies of adipose tissue in humans with special reference to innervation by the sympathetic nervous system [PDF]

, 2009
PhDThis thesis reports the effects in vivo of the sympathetic nervous system (SNS) in human subcutaneous abdominal white adipose tissue (WAT) and other tissues involved in energy storage and utilisation. Cannulation of superficial veins draining skin,
Lawence, Victor
core