Results 71 to 80 of about 444,349 (315)

Transcriptional fingerprinting of "browning" white fat identifies NRG4 as a novel adipokine [PDF]

open access: yes, 2014
Brown adipocytes help to maintain body temperature by the expression of a unique set of genes that facilitate cellular metabolic events including uncoupling protein 1-dependent thermogenesis.
Christian, Mark, Christian, M
core   +1 more source

Cardiometabolic Risk and Epicardial Adipose Tissue [PDF]

open access: yes, 2020
Epicardial adipose tissue (EAT) is a quantifiable and modifiable biomarker. EAT is a marker of visceral adiposity and strongly correlates with fatty liver infiltration and insulin resistance.
Iacobellis, Gianluca   +1 more
core   +1 more source

Differential regulation of gene co-expression modules in muscles and liver of preterm newborns

open access: yesFrontiers in Cell and Developmental Biology
BackgroundNewborns undergo rapid metabolic and organ adaptations after birth, which are compromised in premature newborns, leading to adverse health outcomes.
Petra Janovska   +11 more
doaj   +1 more source

Orbital adipose tissue

open access: yesОфтальмохирургия, 2016
We summarized the results of Russian and foreign researches elucidating embryogenesis, topography and anatomy of different orbital fat pads. It is interesting that adipose tissue from different surgical adipose spaces do not stem from the same germ ...
S. A. Borzenok   +3 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Targeting the Epicardial Adipose Tissue [PDF]

open access: yes, 2020
Epicardial fat (EAT) is the visceral fat depot of the heart. Given its rapid metabolism, organ fat specificity, and simple objective measurability, epicardial fat can serve as a target for pharmaceutical agents targeting the adipose tissue. EAT has shown
Iacobellis, Gianluca
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Investigation of effect of hyperinsulinaemia on adipose tissue microvasculature. [PDF]

open access: yes, 2015
Background: Obesity in Qatar is amongst the highest globally and constitutes a serious health risk. Obese individuals are at greater risk of vascular disease compared to the lean, especially in the insulin resistant state.
Bakhamis, AAA
core  

Adipose tissue: colors, depots and functions

open access: yesОжирение и метаболизм, 2021
Obesity is a chronic disease characterized by excessive accumulation of adipose tissue. The prevalence of obesity and associated diseases has prompted researchers to expand the study of the biology of adipose tissue.
T. I. Romantsova
doaj   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan   +10 more
wiley   +1 more source

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