Results 61 to 70 of about 2,147,082 (312)

Isoenergetic feeding of low carbohydrate-high fat diets does not increase brown adipose tissue thermogenic capacity in rats [PDF]

, 2012
Low-carbohydrate, high-fat (LC-HF) diets are popular for inducing weight loss in overweighed adults. Adaptive thermogenesis increased by specific effects of macronutrients on energy expenditure has been postulated to induce this weight loss.
Bidlingmaier, Martin, Korbinian Pieper (158350), Müller, H.H., Brigitte Mauracher, William Abplanalp (158346), Marc Slawik (152756), Bidlingmaier, M., Ramisch, Juliane, Mauracher, B., Tschöp Matthias H., Mauracher, Brigitte, Ramisch, J., Bidlingmaier Martin, Pieper, Korbinian, Slawik, Marc, Pieper, K., Juliane Ramisch, Maximilian Bielohuby (158339), Bielohuby Maximilian, Müller Hans-Helge, Matthias H Tschöp, Korbinian Pieper, Tschöp, Matthias H., Matthias J Betz, Matthias J. Betz (158336), Beuschlein, Felix, Abplanalp William, Felix Beuschlein, Matthias H. Tschöp (158357), Abplanalp, William, Pieper Korbinian, Brigitte Mauracher (158342), Beuschlein, F., Hans-Helge Müller (158349), Bielohuby, M., Tschöp, M.H., Bielohuby, Maximilian, Müller, Hans-Helge, William Abplanalp, Mauracher Brigitte, Betz, Matthias J., Marc Slawik, Martin Bidlingmaier (150187), Abplanalp, W., Martin Bidlingmaier, Juliane Ramisch (158353), Betz, M.J., Beuschlein Felix, Slawik, M., Maximilian Bielohuby, Slawik Marc, Ramisch Juliane, Hans-Helge Müller, Felix Beuschlein (158361), Betz Matthias J.   +54 more
core   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Transcriptional fingerprinting of "browning" white fat identifies NRG4 as a novel adipokine [PDF]

, 2014
Brown adipocytes help to maintain body temperature by the expression of a unique set of genes that facilitate cellular metabolic events including uncoupling protein 1-dependent thermogenesis.
Christian, Mark, Christian, M
core   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Signals from adipose tissue in morbid obesity and effect on depot specific differences [PDF]

, 2009
Signals from adipose tissue, such as interleukin-6 (IL-6) and asymmetric dimethyl arginine (ADMA), an endogenous nitric oxide inhibitor, explain the link between obesity and metabolic diseases.
Madani, R.
core  

Estimation of CT-derived abdominal visceral and subcutaneous adipose tissue depots from anthropometry in Europeans, South Asians and African Caribbeans [PDF]

, 2013
Background South Asians and African Caribbeans experience more cardiometabolic disease than Europeans. Risk factors include visceral (VAT) and subcutaneous abdominal (SAT) adipose tissue, which vary with ethnicity and are difficult to quantify using ...
Willis Joseph, Hughes, AD, Ian F. Godsland (212035), Peter Whincup (20840), Peter Whincup, Tillin, T, Therese Tillin, Joseph Willis, Sophie V. Eastwood (459934), Tillin Therese, Andrew Wright (459935), Nita Forouhi (459938), Nita Forouhi, Andrew Wright, Joseph Willis (459937), Eastwood Sophie V., Nishi Chaturvedi, Wright, A, Forouhi, N, Ian F Godsland, Nishi Chaturvedi (130777), Hughes Alun D., Eastwood, SV, Wright Andrew, Chaturvedi, N, Whincup, P, John Heasman (459936), Whincup Peter, Godsland, IF, Chaturvedi Nishi, Sophie V Eastwood, Alun D Hughes, Heasman John, Heasman, J, John Heasman, Forouhi Nita, Willis, J, Alun D. Hughes (395075), Therese Tillin (130770), Godsland Ian F.   +39 more
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

15-LOX metabolites and angiogenesis: angiostatic effect of 15(S)-HPETE involves induction of apoptosis in adipose endothelial cells [PDF]

PeerJ, 2014
Inflammation is critical in the dysregulated growth of adipose tissue and associated vascular dysfunctions. 15-Lipoxygenase metabolites, important mediators of inflammation in adipose tissue during obese conditions, may contribute to codependence of ...
Sasikumar J. Soumya, Sheela Binu, Antony Helen, Pallu Reddanna, Perumana R. Sudhakaran   +4 more
doaj   +2 more sources

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J. S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source

Fat compartments in patients with depression: A meta‐analysis

Brain and Behavior, 2021
Introduction Depressive disorders are a common illness worldwide. Major depression is known as a significant predictor of the metabolic syndrome. However, the effects of depression on adipose tissue compartments are controversial.
Alisa S. Cosan, Julietta U. Schweiger, Kai G. Kahl, Bettina Hamann, Michael Deuschle, Ulrich Schweiger, Anna L. Westermair   +6 more
doaj   +1 more source