Results 41 to 50 of about 2,270,278 (313)

The defense of adipose tissue against excess substrate-induced hyperthrophia: Immune system cell infiltration and arrested metabolic activity [PDF]

open access: yes, 2011
Obesity, the excessive accumulation of body fat, is a main defining feature of the metabolic syndrome, and overweight is often an early indication of the future severity and development of associated pathologies.
Alemany, Marià, 1946-, Marià Alemany
core   +1 more source

A novel conjunctive microenvironment derived from human subcutaneous adipose tissue contributes to physiology of its superficial layer

open access: yesStem Cell Research & Therapy, 2021
Background In human subcutaneous adipose tissue, the superficial fascia distinguishes superficial and deep microenvironments showing extensions called retinacula cutis.
Leandra Santos Baptista   +7 more
doaj   +1 more source

Adipose tissue aging is regulated by an altered immune system

open access: yesFrontiers in Immunology, 2023
Adipose tissue is a widely distributed organ that plays a critical role in age-related physiological dysfunctions as an important source of chronic sterile low-grade inflammation. Adipose tissue undergoes diverse changes during aging, including fat depot
Yi-Xiang Zhang   +5 more
doaj   +1 more source

SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding

open access: yesNature Communications, 2016
The clock protein Cry regulates hepatic glucose metabolism. Here the authors show that SREBP1c, activated by insulin signalling after feeding, directly regulates Cry transcription at specific circadian time points, and that Cry represses hepatic glucose ...
Hagoon Jang   +11 more
doaj   +1 more source

Towards clinical translation of upscaled osteogenic grafts using human adipose tissue progenitors [PDF]

open access: yes, 2012
Tissue engineering is an emerging strategy in medical field that focuses on regeneration or replacement of lost or damaged tissue and organs. Most of the tissues in human body have no or limited self renewal and regeneration potential which decrease with
Güven, Sinan
core   +1 more source

A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences [PDF]

open access: yes, 2010
Depot-dependent differences in adipose tissue physiology may reflect specialized functions and local interactions between adipocytes and surrounding tissues.
Kelder, T.A.J.   +45 more
core   +2 more sources

Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population

open access: yesJournal of Cardiovascular Development and Disease, 2023
The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to ...
Joana Ferreira   +12 more
doaj   +1 more source

Autophagy in Adipose Tissue [PDF]

open access: yesObesity Facts, 2012
The possible involvement of the evolutionarily conserved process of autophagy (selfeating) in the pathogenesis of human diseases has been increasingly appreciated in recent years. However, at present, many fundamental questions remain to be answered before autophagy can be considered as a therapeutic target: The biological consequences of activating or
Nitzan, Maixner   +5 more
openaire   +2 more sources

The role of melanocortins and cytokines in human adipose tissue and adipocytes [PDF]

open access: yes, 2007
During the last decades obesity has become a major health problem in developed countries, and more recently also in the developing countries it is seriously affecting parts of the populations.
Hoch, Matthias
core   +1 more source

Evaluation of Protective Effects of Hydroalcoholic Extract Obtained from Cucurbita moschata Skin in Animal Model of Ulcerative Colitis

open access: yesArmaghane Danesh Bimonthly Journal, 2022
Background & aim: Ulcerative colitis is an inflammatory disease of the large intestine that cannot be treated, but its symptoms can be controlled. In traditional medicine, for the basic treatment of colitis, it is necessary to first prevent this abnormal
N Fitras   +4 more
doaj  

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