Results 141 to 150 of about 112,573 (303)

Targeting the PI3K/Akt/NF‐κB axis: Cluster of differentiation 5‐like‐mediated immunometabolic regulation of macrophage polarization in abdominal aortic aneurysm

Journal of Cell Communication and Signaling, Volume 19, Issue 4, December 2025.
Targeting the PI3K/Akt/NF‐κB Axis: CD5L suppresses M1 macrophage polarization and vascular inflammation, thereby attenuating abdominal aortic aneurysm progression. Abstract Abdominal aortic aneurysm (AAA) is a life‐threatening vascular disorder lacking effective pharmacological interventions.
Hemoren Yi, Nan Liu, Zhengyang Wu, Lei Li, Tingting Li, Qixiang Liu, Man Duan, Taihu Wan   +7 more
wiley   +1 more source

Five-year results of endovascular aortic repair used according to instructions for use give a good general outcome for abdominal aortic aneurysm

SAGE Open Medicine, 2019
Objectives: The primary aim of this study was to investigate the rate of sac enlargement and secondary procedures after 5 years when instructions for use are strictly applied with endovascular aortic repair. The secondary aim was to investigate if strict
Runa G Unsgård, Martin Altreuther, Conrad Lange, Tommy Hammer, Erney Mattsson   +4 more
doaj   +1 more source

Duodenal obstruction due to abdominal aortic aneurysm. [PDF]

, 1975
H M Adair
openalex   +1 more source

Splenic Artery Aneurysm in Gaucher Disease: A Hybrid Study Combining Case Report, Scoping Review, and Clinical Survey

JIMD Reports, Volume 66, Issue 6, November 2025.
ABSTRACT Gaucher disease (GD) is a rare lysosomal storage disorder caused by pathogenic variants in the GBA gene. Splenic artery aneurysm (SAA) is an uncommon and underrecognized complication of GD, particularly in the absence of traditional risk factors. SAA carries a high risk of rupture and significant mortality.
Paolo Manzi, Anita Vergatti, Veronica Abate, Nadia Altavilla, Michelina Sibilio, Pietro Venetucci, Paolo Tirelli, Domenico Rendina, Antonio Barbato   +8 more
wiley   +1 more source

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu, Ze‐Yu Cai, Qing‐Le Li, Tao Zhang, Xiang‐Yu Chu, Chang Wang, Qing‐Yi Zhang, Rong Qi   +7 more
wiley   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang, Yujie Shan, Shihong Xu, Jing Wang, Meng Luo, Jiaojiao Zhou, Qishan Chen   +6 more
wiley   +1 more source

Abdominal aortic aneurysm and peptic ulcer. [PDF]

, 1971
G J Prokter
openalex   +1 more source

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen, Yujie Zhu, Xi Yang, JiangBin Wu, Keyuan Chen, Wuqing Huang, Lu Fang, Qi Zhang, Jie Chen, Jianing Gao, Huanhuan Cao, Meifang Wu, Zhihuang Qiu, Yuling Zhang, Yue Shen, Qiuyu Huang, Zhiyong Lin, Lemin Zheng, Liangwan Chen   +18 more
wiley   +1 more source

Acute spontaneous isolated dissection of abdominal aorta

Journal of Research in Medical Sciences, 2009
<ul><li>Aortic dissection occurs when the layers of the aorta separate as a result of extra luminal cavity of blood through an intimal tear. Dissection limited to the abdominal aorta is rare.
Ali Akbar beigi, Reza Eshraghi samani
doaj  

Exiting Surveillance From Abdominal Aortic Aneurysm Screening: The Views of Clinicians, and Men in Surveillance and Their Family Members [PDF]

Health Expect
ABSTRACT Background The NHS Abdominal Aortic Aneurysm (AAA) Screening Programme in England screens men aged 65. Men with small aneurysms enter annual surveillance. The current ‘exit strategy’ is to leave surveillance after 15 years if the aneurysm remains small.
Lumley E, Hughes J, Elstone A, Hall J, MacGregor‐Smith N, Michaels J, Nasim A, Radley S, Shackley P, Stansby G, Wood E, O'Cathain A.   +11 more
europepmc   +2 more sources