Results 181 to 190 of about 376,334 (347)

High‐resolution deep learning DIXON MRI of the sacroiliac joints is non‐inferior to standard MRI in patients with suspected axial Spondyloarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To compare the standard multi‐sequence MRI protocol (sMRI) of the sacroiliac joints with a single high‐resolution deep learning–reconstructed DIXON sequence (DL‐DIXON) in patients with suspected axial spondyloarthritis (axSpA). Methods Seventy‐six patients with chronic low back pain and suspected axSpA underwent clinical, laboratory, and ...
Dominik Deppe   +12 more
wiley   +1 more source

Suprainguinal Lateral Femoral Cutaneous Neurectomy for Recurrent Meralgia Paresthetica: A Technique Guide

open access: yesArthroscopy Techniques, EarlyView.
Abstract Meralgia paresthetica (MP) is a neuropathy caused by injury or compression of the lateral femoral cutaneous nerve (LFCN), presenting as numbness, tingling, or burning pain in the lateral thigh. While surgical decompression has traditionally been a common surgical treatment for MP, recently, fully transecting the LFCN is increasingly becoming ...
Joshua T. Finerty   +3 more
wiley   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić   +8 more
wiley   +1 more source

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh   +5 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins   +23 more
wiley   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

open access: yesBMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng   +10 more
wiley   +1 more source

Effect of Tecar Therapy in the Treatment of Skin Flaccidity and Localized Abdominal Fat-Clinical and Controlled Study. [PDF]

open access: yesDermatol Res Pract
de Almeida S   +10 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy