Results 41 to 50 of about 3,651,303 (328)

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Trauma abdominal fechado: análise dos pacientes vítimas de trauma hepático em um Hospital Universitário de Curitiba

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Determinar as características comuns referentes ao mecanismo de trauma, lesões anatômicas e fisiológicas, dor abdominal e à fratura de costelas das vítimas de trauma hepático contuso, no momento da admissão hospitalar.
Luiz Carlos von Bahten, João Eduardo Nicoluzzi, Márcia Olandoski, Carlos Andrés Rodriguez Pantanali, Ruy Fernando Kuenzer Caetano da Silva   +4 more
doaj   +1 more source

Caracterización de pacientes con trauma abdominal cerrado atendidos en el servicio de cirugía de un hospital general

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Fundamento: el trauma abdominal cerrado provoca grandes dilemas diagnósticos y terapéuticos, dado la necesidad de determinar si se lesionó alguna víscera y es necesario operar o no.Objetivo: caracterizar a los pacientes con trauma abdominal cerrado ...
Eugenio Elio Cruz-Pérez, Igor Almanza-Pérez, Alicia María Yabor-Palomo, Pilar Laborí-Quesada, Jessica Cristian Rodríguez-Santiesteban   +4 more
doaj  

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Isolated Abdominal Injury of Blunt Aortic Trauma: Two Case Reports and Review of the Literature

Journal of Endovascular Resuscitation and Trauma Management, 2018
Background: Injury to the abdominal aorta as part of a blunt injury is a rare event and is normally associated with other abdominal injuries. The management of these injuries can be non-operative, open repair or endovascular repair.
Barak Raguan, Ali Shnaker, Simone Fajer
doaj   +1 more source

Evaluation of Injuries in Patients with Blunt Abdominal Trauma by Ultrasonography taking Computerized Tomography as Gold Standard Imaging Modality-Experience at Liaquat National Hospital [PDF]

JLUMHS, 2018
BACKGROUND: Consequent upon blunt abdominal trauma liver, spleen and kidneys are most vulnerable organs to be affected. Rapid diagnosis and appropriate management are key factors to reduce the risk of preventable death.
Nadia Mohsin, Ameet Jesrani , Roomi Mahmud, Waseem Mehmood Nizamani, Mubarak Ali   +4 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Characteristics of rib fracture patients who require chest computed tomography in the emergency department

BMC Emergency Medicine, 2023
Background The disadvantages and complications of computed tomography (CT) can be minimized if CT is performed in rib fracture patients with high probability of intra-thoracic and intra-abdominal injuries and CT is omitted in rib fracture patients with ...
Woosik Kim, Juhyun Song, Sungwoo Moon, Jooyeong Kim, Hanjin Cho, Jonghak Park, Sungjin Kim, Sejoong Ahn   +7 more
doaj   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source