Results 91 to 100 of about 4,652 (218)

Self‐Assembly of Antigenic Peptide Nanofibrils Templates the Growth of Silica Nanoparticles for Nanovaccines

open access: yesAdvanced Science, EarlyView.
Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang   +6 more
wiley   +1 more source

A Child with Absent Abdominal Muscles [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1909
openaire   +2 more sources

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

open access: yesAdvanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li   +8 more
wiley   +1 more source

Mediating role of inspiratory muscle strength in the relationship between abdominal obesity and lung function in young individuals: a cross-sectional study

open access: yesBMJ Open
Objective This study aimed to explore the mediating role of inspiratory muscle strength between abdominal obesity and lung function in young people.Design Cross-sectional study.Setting This survey was conducted in Peking University Health Science Center,
Shaomei Shang   +4 more
doaj   +1 more source

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

open access: yesAdvanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng   +14 more
wiley   +1 more source

Russian Current Stimulation and Deep Core Muscle Strengthening on Diastasis Rectus Abdominis Muscle in Postpartum Females: A Randomized Controlled Trial

open access: yesArchives of Medicine and Health Sciences
Background and Aim: Postpartum women often experience diastasis recti, causing functional and cosmetic problems. Rehabilitation methods such as Russian current and core strengthening are suggested, but high-level evidence for their effectiveness in this ...
Zankhana Parikh, Arati Mahishale
doaj   +1 more source

Data‐Driven Design of Self‐Adhesive Epidermal Electrodes and Sensors

open access: yesAdvanced Science, EarlyView.
This work presents self‐adhesive, stretchable epidermal electrodes and sensors developed through a data‐driven design framework that integrates artificial neural networks with genetic algorithms. By tailoring optimization objectives, either maximizing electrical conductivity and adhesion or enhancing piezoresistive sensitivity, the study enables the ...
Xuan Li   +10 more
wiley   +1 more source

Pylorus‐Preserving Gastrectomy for Gastric Cancer: Current Evidence and Future Directions

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This review aims to outline the current evidence and future directions of PPG, focusing on the feasibility of extending its application beyond its traditional indications. ABSTRACT Pylorus‐preserving gastrectomy (PPG) is a function‐preserving surgery for clinically T1N0M0 (cT1N0M0) early gastric cancer (EGC) located in the middle third of the stomach ...
Sa‐Hong Kim, Hyuk‐Joon Lee
wiley   +1 more source

Trends, Demographic Characteristics and Seasonal Patterns of Rectal Prolapse Surgery in Japan: A Nationwide Claims‐Based Analysis From 2014 to 2023

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study analyzed nationwide trends, demographic characteristics, and seasonal patterns of rectal prolapse surgery in Japan using healthcare claims data. From 2014 to 2023, age‐adjusted overall and conventional surgeries declined significantly, whereas laparoscopic surgeries increased significantly.
Masamitsu Kido   +9 more
wiley   +1 more source

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