Results 21 to 30 of about 4,652 (218)

Effect of Inspiratory Muscle Training on Diaphragm and Abdominal Wall Muscle Thickness with Fatty Liver Density in Elderly Women: A Randomized Controlled Trial

Medicina
Background and Objectives: Post-menopausal estrogen decline is considered a contributing factor to sarcopenia, and inspiratory muscle training (IMT) may provide benefits in this demographic.
Eda Gökçelik, Coşkun Yılmaz, Cemallettin Budak, Hakan Hüseyin Soylu, Serdar Bayrakdaroğlu, Halil İbrahim Ceylan, Raul Ioan Muntean, Hamza Küçük, Levent Ceylan   +8 more
doaj   +1 more source

Association of low back pain with muscle weakness, decreased mobility function, and malnutrition in older women: A cross-sectional study.

PLoS ONE, 2021
BackgroundLow back pain (LBP) and decreased mobility function are common problem among older people. Muscle weakness has been reported as a risk factor for these conditions, and exercise therapy can improve them.
Satoshi Kato, Satoru Demura, Kazuya Shinmura, Noriaki Yokogawa, Tamon Kabata, Hidenori Matsubara, Yoshitomo Kajino, Kentaro Igarashi, Daisuke Inoue, Yuki Kurokawa, Norihiro Oku, Hiroyuki Tsuchiya   +11 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Characterizing core muscle morphometry in postpartum women with pelvic girdle pain and asymptomatic subjects: a comparative cross-sectional study [PDF]

PeerJ
Background This study aimed to examine the differences in core muscle morphometry and contraction changes between postpartum individuals with and without pelvic girdle pain (PGP).
Ziling Lin, Bo Chen, Ruoling Chen, Xueling Chen, Yanjun Hou, Yanping Liu, Lili Lin, Zhiwei Lin, Xiangbin Wang, Cheng Zeng   +9 more
doaj   +2 more sources

Innovative exercise device for the abdominal trunk muscles: An early validation study. [PDF]

PLoS ONE, 2017
BACKGROUND:Exercise is one of the few treatments that provide significant improvements in chronic low back pain (CLBP). We developed an innovative exercise device for abdominal trunk muscles.
Satoshi Kato, Hideki Murakami, Anri Inaki, Takafumi Mochizuki, Satoru Demura, Junsuke Nakase, Katsuhito Yoshioka, Noriaki Yokogawa, Takashi Igarashi, Naoki Takahashi, Noritaka Yonezawa, Seigo Kinuya, Hiroyuki Tsuchiya   +12 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

A MUSCLE-TENDON TRANSPOSITION FOR PARALYSIS OF THE LATERAL ABDOMINAL MUSCLES IN POLIOMYELITIS [PDF]

The Journal of Bone and Joint Surgery. British volume, 1956
1. A dynamic muscle-tendon transposition is described for supplementing the power of weak lateral abdominal muscles, and the details of the operative technique are given. 2. A clinical assessment of the results in a series of twenty-four patients is given. 3. The indications for the operation in poliomyelitis are suggested.
J M, CLARK, A, AXER
openaire   +2 more sources