Results 31 to 40 of about 1,812,611 (286)

Association of low back pain with muscle weakness, decreased mobility function, and malnutrition in older women: A cross-sectional study.

PLoS ONE, 2021
BackgroundLow back pain (LBP) and decreased mobility function are common problem among older people. Muscle weakness has been reported as a risk factor for these conditions, and exercise therapy can improve them.
Satoshi Kato, Satoru Demura, Kazuya Shinmura, Noriaki Yokogawa, Tamon Kabata, Hidenori Matsubara, Yoshitomo Kajino, Kentaro Igarashi, Daisuke Inoue, Yuki Kurokawa, Norihiro Oku, Hiroyuki Tsuchiya   +11 more
doaj   +1 more source

Association between type 2 diabetes mellitus and body composition based on MRI fat fraction mapping

Frontiers in Public Health
PurposeTo explore the association between type 2 diabetes mellitus (T2DM) and body composition based on magnetic resonance fat fraction (FF) mapping.MethodsA total of 341 subjects, who underwent abdominal MRI examination with FF mapping were enrolled in ...
Qi An, Qin-He Zhang, Yue Wang, Han-Yue Zhang, Yu-Hui Liu, Zi-Ting Zhang, Mei-Ling Zhang, Liang-Jie Lin, Hui He, Yi-Fan Yang, Peng Sun, Zhen-Yu Zhou, Qing-Wei Song, Ai-Lian Liu   +13 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Effect of Inspiratory Muscle Training on Diaphragm and Abdominal Wall Muscle Thickness with Fatty Liver Density in Elderly Women: A Randomized Controlled Trial

Medicina
Background and Objectives: Post-menopausal estrogen decline is considered a contributing factor to sarcopenia, and inspiratory muscle training (IMT) may provide benefits in this demographic.
Eda Gökçelik, Coşkun Yılmaz, Cemallettin Budak, Hakan Hüseyin Soylu, Serdar Bayrakdaroğlu, Halil İbrahim Ceylan, Raul Ioan Muntean, Hamza Küçük, Levent Ceylan   +8 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Characterizing core muscle morphometry in postpartum women with pelvic girdle pain and asymptomatic subjects: a comparative cross-sectional study [PDF]

PeerJ
Background This study aimed to examine the differences in core muscle morphometry and contraction changes between postpartum individuals with and without pelvic girdle pain (PGP).
Ziling Lin, Bo Chen, Ruoling Chen, Xueling Chen, Yanjun Hou, Yanping Liu, Lili Lin, Zhiwei Lin, Xiangbin Wang, Cheng Zeng   +9 more
doaj   +2 more sources

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Innovative exercise device for the abdominal trunk muscles: An early validation study. [PDF]

PLoS ONE, 2017
BACKGROUND:Exercise is one of the few treatments that provide significant improvements in chronic low back pain (CLBP). We developed an innovative exercise device for abdominal trunk muscles.
Satoshi Kato, Hideki Murakami, Anri Inaki, Takafumi Mochizuki, Satoru Demura, Junsuke Nakase, Katsuhito Yoshioka, Noriaki Yokogawa, Takashi Igarashi, Naoki Takahashi, Noritaka Yonezawa, Seigo Kinuya, Hiroyuki Tsuchiya   +12 more
doaj   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans [PDF]

, 2010
peer reviewedAneurysm of the abdominal aorta (AAA) is a particular, specifically localized form of atherothrombosis, providing a unique human model of this disease.
Allaire, E., Thorsteinsdottir, U, Egido, J., Michel, Jérôme, N. Sakalihasan, Swedenborg, J,, J.-B. Michel, Lindholt, J, Michel, JB, Egido, J, Allaire, E, J. Lindholt, J. Swedenborg, J.-L. Martin-Ventura, E. Allaire, Martin-Ventura, J. L., Cockerill, G., U. Thorsteinsdottir, Thorsteinsdottir, U., Treska, V, FAD EU consortium, Lindholt, J., Swedenborg, Jesper, V. Treska, Sakalihasan, Natzi, Sakalihasan, N, null null, Swedenborg, J, G. Cockerill, Michel, J-B, Treska, V., Martin-Ventura, J-L, Martin-Ventura, JL, J. Egido, Cockerill, G   +34 more
core   +1 more source