Results 121 to 130 of about 997,879 (304)

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza   +12 more
wiley   +1 more source

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor   +11 more
wiley   +1 more source

Urine Uric Acid Excretion Levels are Positively Associated with Obesity and Abdominal Obesity in Type 2 Diabetes Patients without Chronic Kidney Disease

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2021
Fengjing Liu, Si Chen, Weijing Zhao, Mingyun Chen, Jiangfeng Ke, Zhihui Zhang, Junxi Lu, Lianxi Li Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai Clinical Center for Diabetes ...
Liu F   +7 more
doaj  

Waist Circumference predicting Cardiovascular Disease in Korean Men and Women [PDF]

open access: yes, 2010
Objective: Obesity and cardiovascular disease (CVD) are closely related and have become increasingly prevalent in Korea. Asians are more prone to obesity-related co-morbidities than Caucasians, even at lower body mass index (BMI) and/or smaller waist ...
Sun Ha Jee, Sat Byul Park
core  

[Efficacy of metformin in abdominal obesity].

open access: yesTerapevticheskii arkhiv, 2014
To study the effect of metformin on metabolic parameters, body weight (BW), and waist circumference (WC) in patients with abdominal obesity (AO).The results of using metformin 2000 mg daily for 3 months in 46 patients with AO. The comparison group consisted of 50 people.
A M Mkrtumian   +4 more
openaire   +2 more sources

Redefining the Surface Anatomy of Major Abdominal Structures in an Adult Population: A Computed Tomography Evaluation

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Inconsistencies exist in anatomy and clinical reference texts regarding the vertebral levels of major abdominal structures. Accurate surface anatomy is essential for diagnostic interpretation and interventional procedures, yet little is known about how health status or pathology may influence the vertebral relationships of abdominal organs ...
Masroor Badshah   +3 more
wiley   +1 more source

Cardio-metabolic and socio-environmental correlates of waist-to-height ratio in German primary schoolchildren: a cross-sectional exploration

open access: yesBMC Public Health, 2018
Background Controversial messages of childhood obesity emerge: Levelling off in terms of body mass index (BMI) is foiled by increases in abdominal obesity.
Eva Vorwieger   +4 more
doaj   +1 more source

Prevalence of Obesity and Incidence of Obesity-Related Comorbidities in Koreans Based on National Health Insurance Service Health Checkup Data 2006–2015

open access: yes, 2018
Background : The prevalence of obesity and related comorbidities is increasing worldwide, including in Korea. The Korean Society for the Study of Obesity released the Obesity Fact Sheet 2017 to address this problem in the Korean population.
Kyungdo Han   +9 more
core   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit   +7 more
wiley   +1 more source

Multivariate linear regression to predict association of non‐invasive arterial stiffness with cardiovascular events

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1141-1150, April 2025.
Abstract Background Arterial stiffness is a crucial factor in determining an increase in systolic blood pressure and pulse pressure and can also predict the development of cardiovascular disease (CVD). The purpose of this study was to examine the relationship between arterial stiffness and future CVD.
Susan Darroudi   +10 more
wiley   +1 more source

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