Results 181 to 190 of about 759,217 (361)

Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti‐PD‐1 Immunotherapy

open access: yesAdvanced Science, EarlyView.
In ovarian tumors with high CMTM4 expression, exosomes transfer CMTM4 to macrophages, upregulating ICAM1 and promoting M2 polarization via p65 nuclear translocation. This suppresses immunity by increasing PD‐1 and Tregs while reducing CD8+ T cells.
Bo Yin   +12 more
wiley   +1 more source

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang   +3 more
wiley   +1 more source

Whole-body metabolism during and after abdominal surgery [PDF]

open access: bronze, 1969
Otto H. Horrelt   +2 more
openalex   +1 more source

β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong   +15 more
wiley   +1 more source

Graft Loss Due to Thrombosis of an Aortic Conduit in a Pediatric Multivisceral Transplant Recipient

open access: yesTransplantation Direct, 2018
Mariya L. Samoylova, MD   +4 more
doaj   +1 more source

Multimodal Prehabilitation in Major Abdominal Surgery-Rationale, Modalities, Results and Limitations. [PDF]

open access: yesMedicina (Kaunas)
Popescu GA   +6 more
europepmc   +1 more source

Amplifying Anti‐Tumor Immune Responses via Mitochondria‐Targeting Near‐Infrared Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
Interfacial Nd3+‐triplet energy transfer enables direct activation of molecular triplets under near‐infrared (NIR) irradiation for reactive oxygen species (ROS) generation. Photodynamic therapy (PDT) exaggerates hypoxia, which initiates subsequent hypoxia‐activated chemotherapy.
Cheng‐Ao Li   +13 more
wiley   +1 more source

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