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Role of intranasal fentanyl in breakthrough pain management in cancer patients [PDF]
Wojciech LeppertDepartment of Palliative Medicine, Poznan University of Medical Sciences, Poznan, PolandAbstract: Fentanyl is a strong opioid analgesic, which is commonly used in the form of a transdermal patch for the treatment of chronic cancer pain ...
Wojciech Leppert
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Background Responses due to laryngoscopy and endotracheal intubation have an effect on blood pressure, heart rate, catecholamines, and oxygen demand of myocardium. These transient changes may affect those with known cardiovascular disease.
Sarayu Ramamurthy, Guruprasad Bettaswamy
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Background: Spinal anesthesia is a regional analgesia that blocks nerve cells in the subarachnoid space by local anesthetic drugs. Bupivacaine is the most common agent, however, the duration of analgesia is often short.
Firdaus Saputra +2 more
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Intracellular calcium release activates carotid body afferents by fentanyl
We recently reported [Peng YJ, Nanduri J, Wang N, Xie Z, Fox AP, Prabhakar NR. Function (Oxf) 6: zqaf020, 2025] that fentanyl activates carotid body (CB) afferents via kappa opioid receptors (KORs), while CB denervation exacerbates, coadministration of ...
Ying-Jie Peng +5 more
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Background: Although fentanyl significantly contributes to opioid-related morbidity and mortality, little is known about the epigenetic changes that may influence long-term neuronal adaptations.
Cameron J. Davidson +10 more
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