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Abuse potential of fentanyl and fentanyl analogues [PDF]
BioImpactsIntroduction: In this perspective review, we evaluated the clinical management of fatal fentanyl overdose in several routes of administration, concentrating on both legally prescribed and illegally produced formulations. Methods: A literature search was conducted on Web of Science, PubMed, and Google Scholar databases, using the following keywords ...
Anusha Thumma +5 more
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A comprehensive evaluation of the potential binding poses of fentanyl and its analogs at the µ-opioid receptor [PDF]
Computational and Structural Biotechnology Journal, 2022 Fentanyl and its analogs are selective agonists of the µ-opioid receptor (MOR). Among novel synthetic opioids (NSOs), they dominate the recreational drug market and are the main culprits for the opioid crisis, which has been exacerbated by the COVID-19 ...
Bing Xie, Alexander Goldberg, Lei Shi
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Veterinary SciencesThe aim of this study was to evaluate the end-tidal concentration of isoflurane required, clinical parameters, intraoperative antinociceptive effect, and postoperative analgesia in cats undergoing ovariohysterectomy, receiving fentanyl, tramadol, or ...
Claudia Interlandi +9 more
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Identifying Fentanyl with Mass Spectral Libraries [PDF]
, 2021 Synthesis, distribution and abuse of fentanyl, a synthetic opioid, has led to a critical worldwide epidemic. Mass spectral library searching for opioids remains unresolved despite being central to law-enforcement involving identification ...
Anthony J., Kearsley, Arun, Moorthy
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BMC Anesthesiology, 2022 Background Fentanyl is an opioid analgesic and is widely used in ovarian cancer patients for pain management. Although increasing evidence has suggested the direct role of fentanyl on cancer, little is known on the effect of fentanyl on ovarian cancer ...
Kai Xiao, Qinghong Zheng, Lei Bao
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Harm Reduction Journal, 2023 Background Fentanyl test strips (FTS) are a commonly deployed tool in drug checking, used to test for the presence of fentanyl in street drug samples prior to consumption.
Kathleen L. Hayes, Marya Lieberman
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Mass Spectral Character of Fentanyl Analogues [PDF]
Fayixue Zazhi, 2019 Objective To provide the reference for the identification of unknown fentanyl analogues by studying the characteristic ions and main fragmentation pathways of fentanyl analogues in the modes of collision induced dissociation （CID） and electron ionization
YAN Jin, HUA Zhen-dong, JIA Wei, et al.
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Effects of neonatal fentanyl on late adolescent opioid-mediated behavior
Frontiers in Neuroscience, 2023 IntroductionBecause of the steady increase in the use of synthetic opioids in women of childbearing age, a large number of children are at risk of exposure to these drugs prenatally or postnatally through breast milk.
Cynthia A. Crawford +7 more
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Journal of Pain and Symptom Management, 2005 Fentanyl, a potent lipid-soluble opioid which was first synthesized more than 40 years ago, is still the most popular opioid used in the perioperative period throughout the world. Fentanyl's introduction, versatility, and popularity have resulted in its use in many acute and chronic pain conditions and a multitude of novel delivery systems in the last ...
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Safety of opioid patch initiation in Australian residential aged care [PDF]
, 2015 Explores opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Abstract Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design:
Lisa Pont +5 more
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