Results 11 to 20 of about 184,026 (339)

Mass Spectral Character of Fentanyl Analogues [PDF]

open access: yesFayixue Zazhi, 2019
Objective To provide the reference for the identification of unknown fentanyl analogues by studying the characteristic ions and main fragmentation pathways of fentanyl analogues in the modes of collision induced dissociation (CID) and electron ionization
YAN Jin, HUA Zhen-dong, JIA Wei, et al.
doaj   +1 more source

Increasing presence of xylazine in heroin and/or fentanyl deaths, Philadelphia, Pennsylvania, 2010–2019

open access: yesInjury Prevention, 2021
Reports from active drug users state that xylazine, the veterinary tranquilliser, has been increasing in the illicit drug supply in Philadelphia. To describe trends and characteristics of unintentional deaths from heroin and/or fentanyl overdose with ...
Jewell Johnson   +3 more
semanticscholar   +1 more source

Perspectives of people in Philadelphia who use fentanyl/heroin adulterated with the animal tranquilizer xylazine; Making a case for xylazine test strips

open access: yesDrug and Alcohol Dependence Reports, 2022
Highlights • Xylazine, a veterinary tranquilizer, is increasingly in heroin/fentanyl in Philadelphia.• While some people like the combination of these drugs, others may not.• Our sample disliked the feeling of xylazine and a perceived risk of violence ...
Megan K. Reed   +5 more
semanticscholar   +1 more source

Evidence of Buprenorphine-precipitated Withdrawal in Persons Who Use Fentanyl

open access: yesJournal of addiction medicine, 2021
Objectives Buprenorphine can precipitate withdrawal in opioid-dependent persons with recent fentanyl use. However, the prevalence of this phenomenon is not clinically established.
Neil B. Varshneya   +4 more
semanticscholar   +1 more source

Sex- and Dose-Dependent Differences in the Development of an Addiction-Like Phenotype Following Extended-Access Fentanyl Self-Administration

open access: yesFrontiers in Pharmacology, 2022
Opioid use disorder (OUD) is a major epidemic in the United States, and fentanyl is a major culprit. The National Institute on Drug Abuse has highlighted an urgent need for research on the risks and outcomes of OUD with fentanyl; a better understanding ...
E. B. Towers, Ben Setaro, W. J. Lynch
semanticscholar   +1 more source

Fentanyl (transmucosal) [PDF]

open access: yesJournal of Pain and Symptom Management, 2012
Therapeutic Reviews aim to provide essential independent information for health professionals about drugs used in palliative and hospice care. Additional content is available on www.palliativedrugs.com. Country-specific books (Hospice and Palliative Care Formulary USA, and Palliative Care Formulary, British and Canadian editions) are also available and
Robert, Twycross   +3 more
openaire   +2 more sources

A comprehensive evaluation of the potential binding poses of fentanyl and its analogs at the µ-opioid receptor

open access: yesComputational and Structural Biotechnology Journal, 2022
Fentanyl and its analogs are selective agonists of the µ-opioid receptor (MOR). Among novel synthetic opioids (NSOs), they dominate the recreational drug market and are the main culprits for the opioid crisis, which has been exacerbated by the COVID-19 ...
Bing Xie, Alexander Goldberg, Lei Shi
doaj   +1 more source

The anomalous pharmacology of fentanyl

open access: yesBritish Journal of Pharmacology, 2021
Fentanyl is a key therapeutic, used in anaesthesia and pain management. It is also increasingly used illicitly and is responsible for a large and growing number of opioid overdose deaths, especially in North America.
E. Kelly   +5 more
semanticscholar   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Perceptions of fentanyl among African Americans who misuse opioids: implications for risk reduction

open access: yesHarm Reduction Journal, 2023
Background Fentanyl is a powerful synthetic opioid that is 50 times more powerful than heroin and has become ubiquitous in the illicit drug supply in the USA.
Khary K. Rigg, Ethan S. Kusiak
doaj   +1 more source

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