Results 31 to 40 of about 74,124 (118)

Pre-induction fentanyl dose-finding study for controlled hypotension during functional endoscopic sinus surgery

Indian Journal of Anaesthesia, 2019
Background and Aims: Fentanyl can facilitate controlled intraoperative hypotension by its sympatholytic effect in patients undergoing functional endoscopic sinus surgery (FESS).
Prabhat Choudhary, Amitabh Dutta, Nitin Sethi, Jayashree Sood, Devinder Rai, Manish Gupta   +5 more
doaj   +1 more source

Dose- and Sex-Dependent Bidirectional Relationship between Intravenous Fentanyl Self-Administration and Gut Microbiota

Microorganisms, 2022
Gut bacteria influence neural circuits in addiction-related behaviors. Given the association between opioid use, gastrointestinal distress, and microbial dysbiosis in humans and mice, we test the hypothesis that interactions between gut bacteria and the ...
Michelle Ren, Shahrdad Lotfipour
doaj   +1 more source

The effect of nitrous oxide in comparison to oxygen combined with fentanyl on the hospitalization time and pain reduction in renal colic patients at emergency department

Journal of Research in Medical Sciences, 2018
Background: Renal colic is a painful medical emergency, needs urgent intervention to reduce pain. Nonsteroidal anti-inflammatory drugs, opioids, and entonox are pain-relieving agents. This study was aimed to compare fentanyl + entonox (nitrous oxide + O2)
Omid Ahmadi, Amir Shirvani Dehkordi, Farhad Heydari, Mohammad Nasr Esfahani, Behzad Mahaki   +4 more
doaj   +1 more source

Pharmacokinetic Profile of Fentanyl in the Koala (Phascolarctos cinereus) after Intravenous Administration, and Absorption via a Transdermal Patch

Animals, 2021
Fentanyl was administered as a single intravenous bolus injection at 5 µg/kg to five koalas and fentanyl plasma concentrations for a minimum of 2 h were quantified by an enzyme-linked immunosorbent assay (ELISA).
Fumie Tokonami, Benjamin Kimble, Merran Govendir   +2 more
doaj   +1 more source

Fentanyl and its derivatives: Pain-killers or man-killers?

Heliyon
Fentanyl is a synthetic μ-opioid receptor agonist approved to treat severe to moderate pain with faster onset of action and about 100 times more potent than morphine.
Jiri Patocka, Wenda Wu, Patrik Oleksak, Romana Jelinkova, Eugenie Nepovimova, Lenka Spicanova, Pavlina Springerova, Suliman Alomar, Miao Long, Kamil Kuca   +9 more
doaj   +1 more source

A Case of Fentanyl Intoxication and Delayed Hypoxic Leukoencephalopathy Caused by Incidental Use of Fentanyl Patch in a Healthy Elderly Man [PDF]

Journal of Neurocritical Care, 2015
Background: Fentanyl intoxication has been reported occasionally since the Fentanyl patch became available. Delayed hypoxic leukoencephalopathy is recognized as a complication of hypoxic events. However, its neuropsychiatric symptoms can be delayed. Case
In Sub Yoo, Sang Hak Lee, Seung-Han Suk
doaj   +1 more source

Naloxone reversal of the cardiorespiratory depressant effects of opioids and mixtures of opioids and stimulants in rats

Frontiers in Pharmacology
Co-use of opioids (e.g., fentanyl) and stimulants (e.g., methamphetamine; METH) contributed to >30% of the almost 106,000 fatal overdoses in the United States in 2023.
Jacqueline M. Vazquez, Robert W. Seaman, Drew Caldron, Gregory T. Collins, Gregory T. Collins   +4 more
doaj   +1 more source

Evaluating fentanyl test strips as a harm reduction strategy in rural and urban counties: study protocol for a randomized controlled trial

Trials
Background Opioid-related fatalities are a leading cause of death in Ohio and nationally, with an increasing number of overdoses attributable to fentanyl. Rapid fentanyl test strips can identify fentanyl and some fentanyl analogs in urine samples and are
Ashley Short Mejia, Gary A. Smith, Soledad A. Fernandez, Bridget Freisthler, Christine Grella, Nichole L. Michaels   +5 more
doaj   +1 more source

Determination of Common Metabolites for Methoxylated Fentanyl Analogs

Forensic Sciences
Background/Objectives: The opioid crisis is an ongoing problem in the United States, and fentanyl analogs play a major role in the issue, as novel fentanyl analogs are constantly being developed.
Jillian Morgan, Candice Bridge
doaj   +1 more source

Association between gene polymorphisms and fentanyl sensitivity in patients undergoing painful orthognathic surgery

Molecular Pain, 2016
Background Fentanyl is often used instead of morphine for the treatment of pain because it has fewer side effects. The metabolism of morphine by glucuronidation is known to be influenced by polymorphisms of the UGT2B7 gene.
Wataru Muraoka DDS, Daisuke Nishizawa PhD, Kenichi Fukuda DDS, PhD, Shinya Kasai PhD, Junko Hasegawa BAgr, Koichi Wajima DDS, PhD, Taneaki Nakagawa DDS, PhD, Kazutaka Ikeda PhD   +7 more
doaj   +1 more source