Results 51 to 60 of about 97,186 (299)
Intravenous fentanyl self-administration in male and female C57BL/6J and DBA/2J mice
Scientific Reports, 2023 The genetic mechanisms underlying fentanyl addiction, a highly heritable disease, are unknown. Identifying these mechanisms will lead to better risk assessment, early diagnosis, and improved intervention.
Michael Leonardo +4 more
doaj +1 more source
Systemic Administration of Tempol Attenuates the Cardiorespiratory Depressant Effects of Fentanyl
Frontiers in Pharmacology, 2021 Fentanyl is a high-potency opioid receptor agonist that elicits profound analgesia and suppression of breathing in humans and animals. To date, there is limited evidence as to whether changes in oxidant stress are important factors in any of the actions ...
Santhosh Baby +9 more
doaj +1 more source
Fentanyl: Could the killer drug reach our streets?
, 2023 In the space of just a few weeks Taoiseach Leo Varadkar, the Minister for Justice Helen McEntee and the head of the Garda National Drugs and Organised Crime Bureau Seamus Boland have all warned about the risk of fentanyl, a lethal, illicit drug ...
Byrne, Louise
core
Evaluation of fentanyl immunoassay test strips for rapid in-situ detection of fentanyl and fentanyl analogs in seized samples and alternative matrices [PDF]
, 2023 Background: Ion mobility spectrometry is used for the rapid detection of drugs at points of security but are unable to differentiate some drugs leading to the instrument alarming for a drug not present in the sample.
Nic Daéid, Niamh; id_orcid +9 more
core +1 more source
American Journal of Industrial Medicine, EarlyView.ABSTRACT Background Work‐related injuries may increase risk for opioid‐related harms. Yet there remains a gap in our understanding of trends in opioid‐related harms over time among injured workers. We estimated trends in hospital encounters for opioid‐related harms among injured workers in Ontario, Canada from 2006 to 2022.
Jeavana Sritharan +4 more
wiley +1 more source
Fentanyl use among people who inject drugs in two large Pacific Northwest metropolitan areas
Harm Reduction JournalBackground We examined fentanyl use and outcomes among people who inject drugs (PWID) in the urban Pacific Northwest (PNW). Methods We conducted secondary analysis of data from the 2022 National HIV Behavioral Surveillance PWID cycle from Seattle, WA and
Lauren Lipira +5 more
doaj +1 more source
Ain Shams Journal of Anesthesiology, 2020 Background Intravenous lidocaine has been shown to be an analgesic and anti-inflammatory medication with modulation of excessive inflammatory response.
Mostafa K. Abdellatif, Tamer H. Ibrahim
doaj +1 more source
High and Hyper: Fentanyl Induces Psychomotor Side-Effects in Healthy Pigs
Animals, 2023 Analgesic effects of fentanyl have been investigated using behavior. The behavioral effects of fentanyl and possible serotonergic influence are largely unknown.
Nora Digranes +2 more
doaj +1 more source
T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy
Annals of Neurology, EarlyView.Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes +6 more
wiley +1 more source
A humanized monoclonal antibody attenuates carfentanil self-administration in nonhuman primates
Drug and Alcohol Dependence ReportsApproximately 70 % of fatal drug overdoses in the United States are attributed to fentanyl and fentanyl analogs. Current medications for reversing overdose and treating opioid use disorder might not be as effective against fentanyl and fentanyl analogs ...
Lindsey K. Galbo-Thomma +5 more
doaj +1 more source