Results 71 to 80 of about 184,026 (339)
British Journal of Clinical Pharmacology, EarlyView.Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
Indian Journal of Anaesthesia, 2019 Background and Aims: Fentanyl can facilitate controlled intraoperative hypotension by its sympatholytic effect in patients undergoing functional endoscopic sinus surgery (FESS).
Prabhat Choudhary +5 more
doaj +1 more source
High and Hyper: Fentanyl Induces Psychomotor Side-Effects in Healthy Pigs
Animals, 2023 Analgesic effects of fentanyl have been investigated using behavior. The behavioral effects of fentanyl and possible serotonergic influence are largely unknown.
Nora Digranes +2 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari +2 more
wiley +1 more source
A humanized monoclonal antibody attenuates carfentanil self-administration in nonhuman primates
Drug and Alcohol Dependence ReportsApproximately 70 % of fatal drug overdoses in the United States are attributed to fentanyl and fentanyl analogs. Current medications for reversing overdose and treating opioid use disorder might not be as effective against fentanyl and fentanyl analogs ...
Lindsey K. Galbo-Thomma +5 more
doaj +1 more source
A Case of Fentanyl Intoxication and Delayed Hypoxic Leukoencephalopathy Caused by Incidental Use of Fentanyl Patch in a Healthy Elderly Man [PDF]
Journal of Neurocritical Care, 2015 Background: Fentanyl intoxication has been reported occasionally since the Fentanyl patch became available. Delayed hypoxic leukoencephalopathy is recognized as a complication of hypoxic events. However, its neuropsychiatric symptoms can be delayed. Case
In Sub Yoo, Sang Hak Lee, Seung-Han Suk
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins +23 more
wiley +1 more source
Correlates of fentanyl preference among people who use drugs in Rhode Island
Harm Reduction JournalBackground Fentanyl is increasingly pervasive in the unregulated drug supply and is a driver of drug overdose deaths in the United States. The aims of this study were to characterize and identify correlates of fentanyl preference among people who use ...
Siena C. Napoleon +8 more
doaj +1 more source
Systemic Administration of Tempol Attenuates the Cardiorespiratory Depressant Effects of Fentanyl
Frontiers in Pharmacology, 2021 Fentanyl is a high-potency opioid receptor agonist that elicits profound analgesia and suppression of breathing in humans and animals. To date, there is limited evidence as to whether changes in oxidant stress are important factors in any of the actions ...
Santhosh Baby +9 more
doaj +1 more source
Wearable electrochemical glove-based sensor for rapid and on-site detection of fentanyl.
Sensors and actuators. B, Chemical, 2019 Rapid, on-site detection of fentanyl is of critical importance, as it is an extremely potent synthetic opioid that is prone to abuse. Here we describe a wearable glove-based sensor that can detect fentanyl electrochemically on the fingertips towards ...
A. Barfidokht +6 more
semanticscholar +1 more source