Results 81 to 90 of about 87,215 (304)

Neuroinflammation and Neurometabolomic Profiling in Fentanyl Overdose Mouse Model Treated with Novel β-Lactam, MC-100093, and Ceftriaxone

Toxics
Opioid-related deaths are attributed to overdoses, and fentanyl overdose has been on the rise in many parts of the world, including the USA. Glutamate transporter 1 (GLT-1) has been identified as a therapeutic target in several preclinical models of ...
Mohammed S. Alasmari, Fawaz Alasmari, Shakir D. Alsharari, Abdullah F. Alasmari, Nemat Ali, Syed Rizwan Ahamad, Abdullah M. Alghamdi, Aban A. Kadi, Alaa M. Hammad, Yousif S. Mohamed Ali, Wayne E. Childers, Magid Abou-Gharbia, Youssef Sari   +12 more
doaj   +1 more source

Colorimetric detection of fentanyl using a supramolecular displacement assay

Fentanyl is a potent synthetic opioid with an alarmingly low lethal dosage of 2 mg. The equipment necessary to detect fentanyl in field settings (e.g., handheld spectrometers) is restricted to highly trained, well-funded, and specialized personnel ...
Patrick, Reust, Piercen, Oliver, Charles R., Mace, Amanda, Code, Andrea C., Mora, Madeline , Vara   +5 more
core   +1 more source

A Review of Toxicological Profile of Fentanyl—A 2024 Update [PDF]

Fentanyl and its analogues are synthetic opioids of varying potencies that are unfortunately heavily abused. Over the last 15 years, fentanyl and its analogues have contributed to the increasing prominence of hospitalisation and numerous deaths due to ...
Williamson, J., Kermanizadeh, A., Ali Kermanizadeh, Jessica Williamson   +3 more
core   +1 more source

Intrauterine Transfusions in Fetuses Affected by Parvovirus B19: Complications, Challenges and Outcomes

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir, Emma Van den Eede, Lone N. Nørgaard, Roland Devlieger, Karin Sundberg, Monique C. Haak, Femke Slaghekke   +6 more
wiley   +1 more source

Oral fentanyl consumption and withdrawal impairs fear extinction learning and enhances basolateral amygdala principal neuron excitatory-inhibitory balance in male and female mice

Addiction Neuroscience
The number of opioid overdose deaths has increased over the past several years, mainly driven by an increase in the availability of highly potent synthetic opioids, like fentanyl, in the un-regulated drug supply.
Anthony M. Downs, Gracianne Kmiec, Zoé A. McElligott   +2 more
doaj   +1 more source

The Effects of Fentanyl on Hepatic Mitochondrial Function.

, 2016
BACKGROUND Remifentanil interferes with hepatic mitochondrial function. The aim of the present study was to evaluate whether hepatic mitochondrial function is affected by fentanyl, a more widely used opioid than remifentanil.
Stephan M. Jakob, Jakob, Stephan, Siamak Djafarzadeh, Madhusudanarao Vuda, Vuda, Madhusudanarao, Jukka Takala, Djafarzadeh, Siamak, Takala, Jukka, Victor Jeger, Jeger, Victor   +9 more
core   +1 more source

MRI in Sheep Model for Myelomeningocele Repair Using a Novel Polymer and Other Dural Patches

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To compare postnatal MRI outcomes after prenatal myelomeningocele repair using three different dural substitutes. Method 32 sheep fetuses were included, with 34.3%(11/32) serving as healthy controls and the remaining undergoing prenatal spinal lumbar defect creation to recreate a myelomeningocele in the fetus.
Usha D. Nagaraj, Marc Oria, Soner Duru, Chia‐Ying Lin, Beth M. Kline‐Fath, Jose L. Peiro   +5 more
wiley   +1 more source

Intraoperative fentanyl in endoscopic procedures and their impact on PACU time and costs

Perioperative Medicine
Background Extended stays in the postanesthesia care unit (PACU) pose challenges in high-volume endoscopies. This study investigates the impact of intraoperative fentanyl use on PACU duration, postoperative pain, and financial implications in outpatient ...
Miho Akabane, Kelsey Kukuruza, Timothy Angelotti, Subhas Banerjee, Kazuo Ando   +4 more
doaj   +1 more source

A comparative study of intravenous fentanyl, oral pregabalin, and a combination of both for attenuation of hemodynamic response to laryngoscopy and tracheal intubation

MRIMS Journal of Health Sciences
Background Responses due to laryngoscopy and endotracheal intubation have an effect on blood pressure, heart rate, catecholamines, and oxygen demand of myocardium. These transient changes may affect those with known cardiovascular disease.
Sarayu Ramamurthy, Guruprasad Bettaswamy
doaj   +1 more source

Fentanyl-induced respiratory depression is attenuated in pregnant patients

, 2017
Xiaofei Cao,* Shijiang Liu,* Jie Sun, Min Yu, Yin Fang, Zhengnian Ding Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China *These authors contributed equally to this work ...
Fang Y, Yu M, Cao X, Liu S, Ding Z, Sun J   +5 more
core