Results 1 to 10 of about 192,819 (168)

MicroRNA-mediated translational pathways are regulated in the orbitofrontal cortex and peripheral blood samples during acute abstinence from heroin self-administration

Advances in Drug and Alcohol Research, 2023
Opioid misuse in the United States contributes to >70% of annual overdose deaths. To develop additional therapeutics that may prevent opioid misuse, further studies on the neurobiological consequences of opioid exposure are needed.
Mary Tresa Zanda, Mary Tresa Zanda, Leila Saikali, Leila Saikali, Paige Morris, Paige Morris, Stephanie E. Daws, Stephanie E. Daws   +7 more
doaj   +1 more source

Engaging the Great Circle: a qualitative study of the Confederated Tribes of Grand Ronde’s mobile medication unit

Annals of Medicine
Background The Confederated Tribes of the Grand Ronde Community of Oregon began a Mobile Medication Unit (MMU) as part of their Great Circle Recovery Opioid Treatment Program (OTP) to address elevated rates of opioid use disorder (OUD) among American ...
Kim A. Hoffman, Chantell Graves, Kelly Rowe, Jennifer Worth, Kellie Pertl, James Laidler, P. Todd Korthuis, Dennis McCarty   +7 more
doaj   +1 more source

Real time, on-site drug checking in low-threshold housing communities

Harm Reduction Journal
Background In recent years, Boston has attempted to increase housing options and reduce overdose risk through the implementation of harm reduction housing (HRH) sites.
Charlie Summers, Joseph Silcox, Sofia Zaragoza, Sabrina Rapisarda, Abigail Edelmann, Avik Chatterjee, Traci C. Green   +6 more
doaj   +1 more source

A qualitative study of the impacts of a government crackdown against revenue sharing between pharmacies and patients in Vancouver, Canada

Discover Public Health
Background The city of Vancouver, Canada has been under a public health emergency driven by the unregulated toxic drug supply since April 2016. Interventions implemented during the crisis have often been driven by electoral interests, and in turn ...
Tyson Singh Kelsall, Garth Mullins, Hannah Dempsey, BC Association of People on Opioid Maintenance Board of Directors, Ryan McNeil, Thomas Kerr   +5 more
doaj   +1 more source

Cannabis combined with oxycodone for pain relief in fibromyalgia pain: a randomized clinical self-titration trial with focus on adverse events

Frontiers in Pain Research
ObjectivesWe determined whether adding cannabis to oxycodone for chronic non-cancer pain management could reduce treatment-related adverse effects (AEs) while maintaining effective analgesia.MethodsIn this open-label study, fibromyalgia patients aged ≥18 
Cornelis Jan van Dam, Cornelis Jan van Dam, Cornelis Kramers, Cornelis Kramers, Cornelis Kramers, Arnt Schellekens, Arnt Schellekens, Arnt Schellekens, Arnt Schellekens, Marcel Bouvy, Marcel Bouvy, Eveline van Dorp, Eveline van Dorp, Mikael A. Kowal, Erik Olofsen, Albert Dahan, Albert Dahan, Albert Dahan, Albert Dahan, Marieke Niesters, Marieke Niesters, Marieke Niesters, Monique van Velzen, Monique van Velzen   +23 more
doaj   +1 more source

Opioid use disorder patients’ perceptions of healthcare delivery platforms

SAGE Open Medicine, 2016
Objectives: To assess the acceptability and quality of web-based videoconferencing telemedicine consultation platform in the treatment of opioid use disorder at TrueNorth Medical Centre.
Uros Rakita, Peter Giacobbe, Chris Cavacuiti   +2 more
doaj   +1 more source

Medicaid expansion and treatment for opioid use disorders in Oregon: an interrupted time-series analysis

Addiction Science & Clinical Practice, 2019
Background The study examined the association of the Affordable Care Act’s 2014 Medicaid expansion on the use of psychosocial services and pharmacotherapies for opioid use disorders among Oregon Medicaid recipients.
Dennis McCarty, Yifan Gu, John W. McIlveen, Bonnie K. Lind   +3 more
doaj   +1 more source

STOP Pain Project—Opioid Response in Pediatric Cancer Patients and Gene Polymorphisms of Cytokine Pathways

Pharmaceutics, 2022
Moderate to severe cancer pain treatment in children is based on the use of weak and strong opioids. Pharmacogenetics play a central role in developing personalized pain therapies, as well as avoiding treatment failure and/or intolerable adverse drug ...
Giada Crescioli, Niccolò Lombardi, Laura Vagnoli, Alessandra Bettiol, Laura Giunti, Valentina Cetica, Maria Luisa Coniglio, Aldesia Provenzano, Sabrina Giglio, Roberto Bonaiuti, Alessandro Mugelli, Maurizio Aricò, Andrea Messeri, Alfredo Vannacci, Valentina Maggini   +14 more
doaj   +1 more source

Comparative study of epidural application of morphine versus gelfoam soaked in morphine for lumbar laminectomy

Journal of Anaesthesiology Clinical Pharmacology, 2014
Background: Epidural application of morphine has been used for postoperative analgesia following spine surgery but short duration of action of single application limits its widespread use. Materials and Methods: One hundred and fifty patients undergoing
Sandeep Kundra, Vishnu Gupta, Hanish Bansal, Anju Grewal, Sunil Katyal, Ashwini Kumar Choudhary   +5 more
doaj   +1 more source

Analgesic Profile in Intensive Observation Room (Ruang Observasi Intensif/ ROI) Dr. Soetomo General Hospital Surabaya

JAI (Jurnal Anestesiologi Indonesia), 2023
Introduction: Pain is a condition that the majority of critical care patients will possibly suffer at some point during their stay in the intensive care unti (ICU). In both medical and surgical ICU patients, the incidence of considerable pain is still 50%
Bunga Priscilla Rotua Manurung, Maulydia Maulydia, Maftuchah Rochmanti, Nancy Margarita Rehatta   +3 more
doaj   +1 more source