Results 11 to 20 of about 303,816 (301)

Preoperative Risk Factors for Opioid Use Predict Self-Reported Health and Function Up to 6 Months After Anterior Cruciate Ligament Reconstruction. [PDF]

Arthrosc Sports Med Rehabil
Purpose To identify risk factors that predict the need for rescue opioid use and patient‐reported outcomes following an opioid‐limiting postoperative analgesia protocol after anterior cruciate ligament reconstruction. Methods This prospective cohort study recruited 44 patients undergoing primary arthroscopic‐assisted anterior cruciate ligament ...
Neufeld EV, DeGouveia W, Pinpin C, Zinner M, Sayegh MJ, Meade MJ, Rokito SE.   +6 more
europepmc   +2 more sources

Cannabis-opioid interaction in the treatment of fibromyalgia pain: an open-label, proof of concept study with randomization between treatment groups: cannabis, oxycodone or cannabis/oxycodone combination—the SPIRAL study

Trials, 2023
Background Opioids continue to be widely prescribed for chronic noncancer pain, despite the awareness that opioids provide only short-time pain relief, lead to dose accumulation, have numerous adverse effects, and are difficult to wean. As an alternative,
Cornelis Jan van Dam, Monique van Velzen, Cornelis Kramers, Arnt Schellekens, Erik Olofsen, Marieke Niesters, Albert Dahan   +6 more
doaj   +1 more source

Extension for Community Healthcare Outcomes (ECHO) Chronic Pain & Opioid Stewardship in Northwestern Ontario: A Thematic Analysis of Patient Cases

Canadian Journal of Pain, 2022
Background Chronic pain (CP) is a debilitating disease that reduces quality of life, decreases productivity, and has become a primary cause of health care resource consumption.
Patricia A. Poulin, Yaadwinder Shergill, Adrian Grebowicz, Inês Almeida, Rosemee Cantave, Bryan MacLeod, Tim Larocque, Donna Garstin, Sarah F. Fitzgerald, Joshua A. Rash   +9 more
doaj   +1 more source

HealthCare educational differences in pain management, adverse childhood experiences and their relationship to substance use disorder education

Substance Abuse Treatment, Prevention, and Policy, 2022
Background In order to assist the State of Ohio in the United States in addressing the opioid epidemic, the Ohio Attorney General appointed experts in a variety of academic disciplines to the Scientific Committee on Opioid Prevention and Education (SCOPE)
Myriam Shaw Ojeda, Aleda M. H. Chen, Tessa Miracle, Elizabeth Delaney, Caroline E. Freiermuth, Jon E. Sprague   +5 more
doaj   +1 more source

Impact of Chronic Alcohol and Opioid Dependence on Biochemical Parameters: A Retrospective Case Control Study from a Tertiary Care Treatment Center in North India [PDF]

Addiction and Health, 2021
Background: Assessment of biochemical parameters can help in the comprehensive management of patients with substance use disorders (SUDs). The aim of this study was to analyse the biochemical parameters of patients with alcohol and opioid dependence at ...
Rizwana Quraishi, Siddharth Sarkar, Raka Jain   +2 more
doaj   +1 more source

Drug use patterns and factors related to the use and discontinuation of medications for opioid use disorder in the age of fentanyl: findings from a mixed-methods study of people who use drugs

Substance Abuse Treatment, Prevention, and Policy, 2023
Background Medications for opioid use disorder (MOUD; methadone, buprenorphine, naltrexone) are the most effective treatments for OUD, and MOUD is protective against fatal overdoses.
Jaclyn M. W. Hughto, Abigail Tapper, Sabrina S. Rapisarda, Thomas J. Stopka, Wilson R. Palacios, Patricia Case, Joseph Silcox, Patience Moyo, Traci C. Green   +8 more
doaj   +1 more source

Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonist [PDF]

, 2013
Since the discovery of the endomorphins (EM), the postulated endogenous peptide agonists of the mu-opioid receptors, several analogues have been synthesized to improve their binding and pharmacological profiles.
Murányi Marianna, Szűcs, Mária, Dochnal Roberta, Kicsi Emese, Kicsi, Emese Gabriella, Fábián Gabriella, Szabó Gyula, Szabó, Gyula, Zentai, András, Bozó, Beáta, Fábián, Gabriella, Birkás Erika, Cinar Resat, Bozó Bea, Birkás, Erika, Kékesi Orsolya Sára, Cinar, Resat, Tóth, Géza, Mácsai Mónika, Mácsai, Mónika, Kékesi, Orsolya, Dochnal, Roberta Beatrix, Tóth Géza, Szűcs Mária, Murányi, Marianna, Zentai András   +25 more
core   +2 more sources

Alternatives to Arrest for Illicit Opioid Use: A Joint Criminal Justice and Healthcare Treatment Collaboration

Substance Abuse: Research and Treatment, 2020
Opioid overdoses continue to be a leading cause of death in the US. This public health crisis warrants innovative responses to help prevent fatal overdose.
Andrea J Yatsco, Rachel D Garza, Tiffany Champagne-Langabeer, James R Langabeer   +3 more
doaj   +1 more source

Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-laboring myometrium [PDF]

, 2013
The existence of opioid receptors in mammalian myometrial tissue is now widely accepted. Previously enkephalin degrading enzymes have been shown to be elevated in pregnant rat uterus and a met-enkephalin analogue has been shown to alter spontaneous ...
McMorrow, Jason P., Carey, Michael F., Campion, Deirdre P., O\u27Connor, J. J., Fanning, Rebecca A., O'Connor, J. J.   +5 more
core   +1 more source

The Rural Opioid Initiative Consortium description: providing evidence to Understand the Fourth Wave of the Opioid Crisis

, 2022
OBJECTIVE: To characterize and address the opioid crisis disproportionately impacting rural U.S. regions. METHODS: The Rural Opioid Initiative (ROI) is a two-phase project to collect and harmonize quantitative and qualitative data and develop tailored ...
Stopka, Thomas J., Friedmann, Peter D., Feinberg, Judith, Westergaard, Ryan P., Tsui, Judith I., Cooper, Hannah L. F., Fredericksen, Rob, Rudolph|, Abby E. Rudolph, Joseph A. C. Delaney, Pho, Mai T., Thomas J. Stopka, Allen, Todd M., P. Todd Korthuis, Todd M. Allen, Hannah L. F. Cooper, Vivian F. Go, Seal, David W., Young, April M., Smith, Gordon S., Wiley D. Jenkins, Gordon S. Smith, Korthuis, P. T., null null, David W. Seal, Crane, Heidi M., Jenkins, Richard A., Miller, William C., Ryan P. Westergaard, Delaney, Joseph A. C., Jenkins, Wiley D., William A. Zule, Judith I. Tsui, Mai T. Pho, Rob Fredericksen, Judith Feinberg, Heidi M. Crane, Rudolph, Abby E., Nance, Robin M., Richard A. Jenkins, Robin M. Nance, Whitney, Bridget M., William C. Miller, Go, Vivian F., Bridget M. Whitney, April M. Young, Peter D. Friedmann, Rudolph, Abby, Korthuis, P. Todd, Zule, William A.   +49 more
core   +1 more source