Results 31 to 40 of about 303,816 (301)

MicroRNA-mediated translational pathways are regulated in the orbitofrontal cortex and peripheral blood samples during acute abstinence from heroin self-administration

Advances in Drug and Alcohol Research, 2023
Opioid misuse in the United States contributes to >70% of annual overdose deaths. To develop additional therapeutics that may prevent opioid misuse, further studies on the neurobiological consequences of opioid exposure are needed.
Mary Tresa Zanda, Mary Tresa Zanda, Leila Saikali, Leila Saikali, Paige Morris, Paige Morris, Stephanie E. Daws, Stephanie E. Daws   +7 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Real time, on-site drug checking in low-threshold housing communities

Harm Reduction Journal
Background In recent years, Boston has attempted to increase housing options and reduce overdose risk through the implementation of harm reduction housing (HRH) sites.
Charlie Summers, Joseph Silcox, Sofia Zaragoza, Sabrina Rapisarda, Abigail Edelmann, Avik Chatterjee, Traci C. Green   +6 more
doaj   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

National opioid pharmacotherapy statistics 2014 [PDF]

, 2015
Summary Dependence on opioid drugs is associated with a range of health and social problems that affect individual drug users, their family and friends, and the wider public.
Australian Institute of Health and Welfare
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Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai, Jessica Fitzpatrick, Jing Li, Eric Roberts, Patricia Katz, Laura Plantinga, Gabriela Schmajuk, Jinoos Yazdany   +7 more
wiley   +1 more source

A qualitative study of the impacts of a government crackdown against revenue sharing between pharmacies and patients in Vancouver, Canada

Discover Public Health
Background The city of Vancouver, Canada has been under a public health emergency driven by the unregulated toxic drug supply since April 2016. Interventions implemented during the crisis have often been driven by electoral interests, and in turn ...
Tyson Singh Kelsall, Garth Mullins, Hannah Dempsey, BC Association of People on Opioid Maintenance Board of Directors, Ryan McNeil, Thomas Kerr   +5 more
doaj   +1 more source

Cannabis combined with oxycodone for pain relief in fibromyalgia pain: a randomized clinical self-titration trial with focus on adverse events

Frontiers in Pain Research
ObjectivesWe determined whether adding cannabis to oxycodone for chronic non-cancer pain management could reduce treatment-related adverse effects (AEs) while maintaining effective analgesia.MethodsIn this open-label study, fibromyalgia patients aged ≥18 
Cornelis Jan van Dam, Cornelis Jan van Dam, Cornelis Kramers, Cornelis Kramers, Cornelis Kramers, Arnt Schellekens, Arnt Schellekens, Arnt Schellekens, Arnt Schellekens, Marcel Bouvy, Marcel Bouvy, Eveline van Dorp, Eveline van Dorp, Mikael A. Kowal, Erik Olofsen, Albert Dahan, Albert Dahan, Albert Dahan, Albert Dahan, Marieke Niesters, Marieke Niesters, Marieke Niesters, Monique van Velzen, Monique van Velzen   +23 more
doaj   +1 more source

National opioid pharmacotherapy statistics annual data collection 2012 [PDF]

, 2013
On a snapshot day in 2012, almost 47,000 clients received pharmacotherapy treatment for their opioid dependence at 2,226 dosing points around Australia, this report finds.SummaryAlmost 47,000 Australians received pharmacotherapy treatment for their ...

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