Results 101 to 110 of about 184,026 (339)

Opioids Delay Healing of Spinal Fusion: A Rabbit Posterolateral Lumbar Fusion Model [PDF]

open access: yes, 2018
Background Context Opioid use is prevalent in the management of pre- and postoperative pain in patients undergoing spinal fusion. There is evidence that opioids downregulate osteoblasts in vitro, and a previous study found that morphine delays the ...
Briley, Karen C.   +5 more
core   +1 more source

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

open access: yesIbrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Determination of Common Metabolites for Methoxylated Fentanyl Analogs

open access: yesForensic Sciences
Background/Objectives: The opioid crisis is an ongoing problem in the United States, and fentanyl analogs play a major role in the issue, as novel fentanyl analogs are constantly being developed.
Jillian Morgan, Candice Bridge
doaj   +1 more source

Fentanyl vapor self-administration model in mice to study opioid addiction

open access: yesScience Advances, 2020
Fentanyl vapor self-administration in mice provides a novel and noninvasive model to study opioid addiction. Intravenous drug self-administration is considered the “gold standard” model to investigate the neurobiology of drug addiction in rodents ...
Khaled Moussawi   +9 more
semanticscholar   +1 more source

External cephalic version outcomes with tocolysis and sedation: A 10‐year retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the effectiveness and safety of external cephalic version (ECV) performed with tocolysis and sedation or spinal anesthesia, and to identify predictors of ECV success, complications, and delivery outcomes after successful ECV. Methods This 10‐year cohort study included 990 pregnant women with term non‐cephalic presentation
Javier Sánchez‐Romero   +7 more
wiley   +1 more source

Fentanyl, carfentanil and other fentanyl analogues in Canada’s illicit opioid supply: A cross-sectional study

open access: yesDrug and Alcohol Dependence Reports
Background: Despite the increase in fentanyl-involved overdose deaths in Canada, there have been no national-level studies evaluating the proportion of illicit opioids containing fentanyl or fentanyl analogues in Canada.
Robert A. Kleinman
doaj   +1 more source

Noradrenergic Mechanisms in Fentanyl-Mediated Rapid Death Explain Failure of Naloxone in the Opioid Crisis

open access: yesJournal of Pharmacology and Experimental Therapeutics, 2019
In December 2018, the Centers for Disease Control declared fentanyl the deadliest drug in America. Opioid overdose is the single greatest cause of death in the United States adult population (ages 18–50), and fentanyl and its analogs [fentanyl/fentanyl ...
Randy Torralva, A. Janowsky
semanticscholar   +1 more source

High concentrations of illicit stimulants and cutting agents cause false positives on fentanyl test strips

open access: yesHarm Reduction Journal, 2020
Background The opioid epidemic has caused an increase in overdose deaths which can be attributed to fentanyl combined with various illicit substances. Drug checking programs have been started by many harm reduction groups to provide tools for users to ...
Tracy-Lynn E. Lockwood   +2 more
semanticscholar   +1 more source

Case Report and Literature Review: Interventional Management of Erythromelalgia. [PDF]

open access: yes, 2019
Erythromelalgia is a rare and very difficult to treat pain syndrome that usually presents as severe bilateral burning pain in the extremities. Here we present a case of a 34-year-old female with erythromelalgia who we treated successfully with a lumbar ...
Chinn, Gregory, Guan, Zhonghui
core  

Things We Do for No Reason™: Withholding opioids among patients with acute pain and opioid use disorder

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Hospitalists care for patients with acute pain who have an opioid use disorder and require pain management. Hospitalists may withhold opioids for acute pain due to a variety of reasons. However, adequate pain management in patients with opioid use disorder, including with opioids, is the standard of care. This piece explains how to best manage
Anna‐Maria South   +2 more
wiley   +1 more source

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