Results 111 to 120 of about 87,215 (304)

Evaluation of in vivo and in vitro effects of fentanyl by transcriptomic investigations (RNA-Seq)

openL'oppioide sintetico fentanyl è uno dei principali responsabili dell'attuale crisi di dipendenza da oppioidi. È uno degli analgesici oppioidi più comunemente somministrati a pazienti sottoposti a interventi chirurgici o per la gestione del dolore ...
GAVIOLI, LAURA
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Intravenous Fentanyl is Exhaled and the Concentration Fluctuates with Time

, 2009
Previous studies have reported that fentanyl is eliminated predominantly by hepatic biotransformation, and that some is eliminated unchanged in urine and stools. No reports have described the elimination of fentanyl via the lungs.
Li, E. Y., 李恩有, Li, P., Xu, G. W., Gong, Y. L., Wang, C. S., Wang, H.   +6 more
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Temporal and geographical patterns of nitazene detections in drug samples and biospecimens in the United States, 2019–2024

Addiction, EarlyView.
Abstract Background and aims Nitazenes are a novel subclass of synthetic opioids that have been increasingly implicated in the United States (US) overdose crisis. Despite their growing presence in the illicit drug supply, national trends have not been systematically evaluated.
David T. Zhu, Nicole D. Fitzgerald, Joseph J. Palamar, Alex J. Krotulski   +3 more
wiley   +1 more source

Intracellular calcium release activates carotid body afferents by fentanyl

Function
We recently reported [Peng YJ, Nanduri J, Wang N, Xie Z, Fox AP, Prabhakar NR. Function (Oxf) 6: zqaf020, 2025] that fentanyl activates carotid body (CB) afferents via kappa opioid receptors (KORs), while CB denervation exacerbates, coadministration of ...
Ying-Jie Peng, Oren Kabil, Ning Wang, Zheng Xie, Aaron P. Fox, Nanduri R. Prabhakar   +5 more
doaj   +1 more source

Fentanyl and Dezocine Associated Application Enhance the Analgesic Effect in Female Patients: A Randomized, Double-blinded, Prospective, Control Study

, 2013
: To evaluate the analgesia effect and side effects of dezocine and fentanyl associated application in female patients, two hundred and forty female patients, American Society of Anesthesiologists (ASA) I～II, aged 18～45 years, weight 50～70 kg, scheduled ...
Ali Li, Zhentao Sun, Lijun Miao, Xueping Han Fentanyl, Chunyao Yang, Dezocine Associated Application, Xueping Han   +6 more
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COMPARATIVE STUDY OF DILUTED FENTANYL, KETAMINE HYDROCHLORIDE AND PRIMING DOSE OF FENTANYL CITRATE ON CESSATION OF FENTANYL INDUCED COUGH (FIC)

, 2018
Fentanyl is commonly used as a preinduction adjunct to general anaesthesia. Incidence of fentanyl induced cough varies between 18-65%. Aims of the study are to evaluate the occurrence rate and severity of fentanyl induced cough and comparison of ...
Dr. Vidhi D Kantesariya, Dr. Kinna G Shah, Dr. Bipin M Patel
core   +1 more source

Healthcare utilization and mortality after overdose prevention site closure: A linked cohort analysis using segmented difference‐in‐differences time series

Addiction, EarlyView.
Abstract Background and aims Evidence regarding the impacts of supervised drug consumption services (SDC) remains mixed, and few evaluations have used individual‐level, linkable health data to examine service withdrawal. In September 2024, the Red Deer overdose prevention site (OPS) in Alberta, Canada, was scheduled for closure, with operations ceasing
Nathaniel Day, Kym Kaufmann, Daniel John Alexander Devoe, Vanja Grubac, Alessia DiMarzo, Haisa Osmanli, Vanessa Norton, Shelly Vik, Nickie Mathew, Robert Lawrence Tanguay, Anees Bahji   +10 more
wiley   +1 more source

Fentanyl transmucosal tablets: current status in the management of cancer-related breakthrough pain

, 2012
Eric Prommer, Brandy FicekDivision of Hematology/Oncology, Mayo Clinic College of Medicine, Mayo Clinic Hospital, Scottsdale, AZ, USAAbstract: Breakthrough pain is a newly recognized pain category that was first described by Portenoy and Hagen in 1990 ...
Prommer E, Ficek B
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What anabolic–androgenic steroids reveal about the limits of current harm reduction models

Addiction, EarlyView.
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski, Jason M. Nagata, Suzanne Nielsen   +2 more
wiley   +1 more source

Addict Behav [PDF]

BackgroundThe rate of overdose deaths caused by fentanyl-contaminated heroin (FCH) use is increasing rapidly in the United States. We examined risk factors for exposure to FCH and experiences with FCH use among young adult non-medical prescription ...

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