Results 41 to 50 of about 94,309 (299)

Fentanyl for labour pain management: a scoping review

open access: yesBMC Pregnancy and Childbirth, 2022
Background Labour pain has been identified as an important reason for women to prefer caesarean section (CS). Fentanyl is one of the short acting opioids recommended by World Health Organization for pain relief during labour. This study aimed to identify
Kyaw Lwin Show   +9 more
doaj   +1 more source

BUMPS: Best use of medicines in pregnancy - Fentanyl.

open access: yes, 2022
This factsheet has been written for members of the public by the UK Teratology Information Service (UKTIS). UKTIS is a not-for-profit organisation funded by Public Health England on behalf of UK Health Departments.

core  

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba   +25 more
wiley   +1 more source

Higher doses of naloxone are needed in the synthetic opioid era

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2019
There has been a dramatic increase of deaths due to illicit fentanyl. We examined the pharmacology of fentanyl and reviewed data on the number of repeat doses of naloxone used to treat fentanyl overdoses.
Ronald B. Moss, Dennis J. Carlo
doaj   +1 more source

Investigation of monoclonal antibody CSX-1004 for fentanyl overdose

open access: yesNature Communications, 2023
The opioid crisis in the United States is primarily driven by the highly potent synthetic opioid fentanyl leading to >70,000 overdose deaths annually; thus, new therapies for fentanyl overdose are urgently needed. Here, we present the first clinic-ready,
Paul T. Bremer   +3 more
doaj   +1 more source

Electrophysiological effects of fentanyl, halothane and isoflurane on guinea-pig isolated ventricular myocytes

open access: yes, 2002
Ischaemic periods which lust only several minutes can result in a reversible reduction in cardiac contractility known as cardiac stunning. This is a potentially dangerous condition since arrhythmias and left ventricular failure are common in the stunned ...
Goddard, Helen   +2 more
core   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

open access: yesAdvanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin   +8 more
wiley   +1 more source

Spectral Barcoding for the Detection of Fentanyl and Fentanyl Analogs Using Raman Spectroscopy

open access: yesApplied Spectroscopy Practica
Fentanyl and fentanyl analogs are the drugs most often implicated in opioid overdose fatalities. Law and drug enforcement agencies are actively working to remove fentanyl-containing drugs from circulation; however, detection in the field can be ...
Phillip G. Wilcox   +4 more
doaj   +1 more source

Intravenous fentanyl self-administration in male and female C57BL/6J and DBA/2J mice

open access: yesScientific Reports, 2023
The genetic mechanisms underlying fentanyl addiction, a highly heritable disease, are unknown. Identifying these mechanisms will lead to better risk assessment, early diagnosis, and improved intervention.
Michael Leonardo   +4 more
doaj   +1 more source

Comparative study of haemodynamic effects of intravenous ketamine-fentanyl and propofol-fentanyl for laryngeal mask airway insertions in children undergoing herniotomy under general anaesthesia in a nigerian tertiary hospital

open access: yesNigerian Postgraduate Medical Journal, 2022
Background: Insertion of laryngeal mask airway (LMA) with propofol in children may cause hypotension, laryngospasm and apnoea. Ketamine and fentanyl have been combined separately with propofol to prevent depression of cardiovascular system during LMA ...
Ajibade Okeyemi   +5 more
doaj   +1 more source

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