Results 251 to 260 of about 12,635,097 (355)

Associations Between Spiritual Sensitivity, Compassion, and Humanistic Practice Ability in Nurses: A Mediation Analysis. [PDF]

Int Nurs Rev
Kaplan F, Aslan H.
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Rapid and repeated evolution of increased competitive ability in a global invader. [PDF]

Nat Commun
Nagy DU, Callaway RM, Luke Flory S, Barratt CD, Durka W, Lekberg Y, Lucas MS, Michalski SG, Onstein RE, Pal RW, Selke J, Thoma AE, Al-Gharaibeh MM, Al-Namazi AA, Andraca-Gómez G, Olsson PA, Baasanmunkh S, Babaei S, Bastida F, Bennett JA, Brunharo C, Cullen DA, Donnelly RC, Ennis A, Ensing DJ, Eren Ö, Fazlioglu F, Filep R, Flessner M, Frazee LJ, González L, Gudžinskas Z, Matt Guilliams C, Hajdari A, Haramoto ER, Haughian SR, Mason Heberling J, Hensen I, Holden EM, Jandová K, Jhala A, Jia X, Jun L, Kaproth MA, Kassem H, Khabbach A, Khasa DP, Koski MH, Kožić K, Krigas N, La Bella G, Lasky JR, Lee B, Leger E, Lemly JM, Libiad M, Lorenzo P, Lozano V, Lucero JE, Makhkamov T, Marchante E, Marchante H, Marshall V, Moffat CE, Moore AJ, Nagy S, Nersesyan A, Novikov A, Okada M, Oprea A, Otfinowski R, Papikyan A, Proctor CA, Ramula S, Rauschert ESJ, Reatini B, Rixen C, Rush S, Rutten G, Sadeghpour A, Samartza I, Sarmati S, Scheepens JF, Shah MA, Sheng M, Sikkema P, Silliman C, Slate ML, St Clair SB, Stein C, Stevermer K, Suzuki SN, Tashpulatov Y, Tsunoda T, Turginov O, Vakhlamova T, van Dam NM, Wagner V, Westberg L, Xiao S, Zhang Z, Rosche C.   +101 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Cohort profile: the Swedish Evaluation Through Follow-up Study of Learning Later in Life (UGU-LIFE). [PDF]

BMJ Open
Hansson I, Berg AI, Bjälkebring P, Buratti S, Burén J, Hassing L, Jonsson AC, Jonsson L, Lindwall M, Segerberg A, Thorvaldsson V, Landén M, Klapp A, Lövdén M.   +13 more
europepmc   +1 more source

Research on the student-centered research feedback experimental teaching model to enhance the effectiveness of pharmacology experimental teaching. [PDF]

Medicine (Baltimore)
Miao C, Chen J, Li Y, Xia A, Song Y, Xu C, Mao Y, Wang X.   +7 more
europepmc   +1 more source