Results 141 to 150 of about 208,281 (313)
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez+34 more
wiley +1 more source
Abnormal high density lipoproteins of abetalipoproteinemia: relevance to normal HDL metabolism
We investigated high density lipoprotein (HDL) subfractions in abetalipoproteinemia (ABL) using rate zonal ultracentrifugation. In ABL, HDL2 is the major subfraction, 65% of total mass compared to less than 10% in normal subjects with similar HDL levels.
R J Deckelbaum+4 more
doaj
TP‐0903 exerts the antitumor effects through diverse cell‐specific mechanisms, including apoptosis, ferroptosis, and cell cycle disruption. These insights underline the potential of TP‐0903 as a therapeutic agent for hematological malignancies and emphasize the need for further research to fully elucidate the molecular targets of TP‐0903 and optimize ...
Tomoko Kimura‐Hyoda+10 more
wiley +1 more source
Erklärung. an den k. k. Oesterreichischen Feld‐Apotheken‐Senior Herrn Dr. Abl in Beziehung auf die Redaction des Archivs der Pharmacie [PDF]
L. F. Bley
openalex +1 more source
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far+4 more
wiley +1 more source
Detection of chimeric BCR-ABL genes on bone marrow samples and blood smears in chronic myeloid and acute lymphoblastic leukemia by in situ hybridization [PDF]
Martin Bentz+6 more
openalex +1 more source
Treatment‐Free Remission in Chronic Myeloid Leukemia: Revisiting the “W” Questions
ABSTRACT Chronic myeloid leukemia (CML) has undergone a transformation from a fatal disease to a chronic, manageable condition with the advent of tyrosine kinase inhibitors (TKIs), particularly imatinib. This shift has significantly improved survival rates, and for some patients, achieving deep molecular response (DMR) has made treatment‐free remission
Antonella Bruzzese+9 more
wiley +1 more source
Antimicrobial blue light (aBL) is a promising non-antibiotic approach to fighting multidrug-resistant bacteria. However, the complete mechanism of aBL action is not fully understood yet.
Beata Kruszewska-Naczk+4 more
doaj +1 more source
BCR-ABL protein expression in peripheral blood cells of chronic myelogenous leukemia patients undergoing therapy [PDF]
JQ Guo+9 more
openalex +1 more source