Results 121 to 130 of about 793,672 (364)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Sub-debris melt rates on southern Inylchek Glacier, central Tian Shan [PDF]

, 2008
Melt rates of glacier surfaces are strongly influenced by the existence of a debris cover. Dependent on thickness and other physical parameters the debris layer can enhance or reduce ablation as compared to bare ice conditions.
Hagg, Wilfried, Helm, Achim, Lambrecht, Astrid, Mayer, Christoph   +3 more
core   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Atrial Fibrillation Triggered by Premature Ventricular Complexes

JACC: Case Reports, 2020
Atrial fibrillation (AF) is a triggered rhythm, and ablation of the trigger is a common strategy for rhythm control. We describe a patient with symptomatic AF who was found to have episodes of AF triggered by premature ventricular complexes, likely by ...
Matthew Bocchese, MD, Hardik Mangrolia, MD, Anuj Basil, MD, Chethan Gangireddy, MD, Edmond Cronin, MD, George A. Yesenosky, MD, Richard M. Greenberg, MD, Joshua M. Cooper, MD, Isaac R. Whitman, MD   +8 more
doaj  

Cardioneuroablation in the treatment of neurally mediated reflex syncope: a review of the current literature

Türk Kardiyoloji Derneği Arşivi, 2017
Objective: An imbalance between parasympathetic and sympathetic tone is a main cause of neurally mediated reflex syncope (NMRS). These patients may be very symptomatic and the condition may require cardiac pacemaker implantation.
Tolga Aksu, Tümer Erdem Güler, Serdar Bozyel, Kazım Serhan Özcan, Kıvanç Yalın, Ferit Onur Mutluer   +5 more
doaj   +1 more source

Micro-Structuring, Ablation and Defect Generation in Graphene with Femtosecond Pulses [PDF]

arXiv, 2019
Femtosecond micromachining offers a contact-free and mask-less technique for material patterning. With ultrafast laser irradiation, permanent modifications to the properties of single layer graphene through material ablation or defect introduction can be induced. Multiple femtosecond pulse interactions with a single layer graphene are studied and a low
arxiv  

Radiation and Ablation Cooling for Manned Reentry Vehicles [PDF]

, 1960
The necessity of reducing heat transfer to reentry vehicles has led I to the consideration of both radiative and ablation shields. The paper reviews briefly the heating problems for manned vehicles and the means whereby ablation and radiation afford ...
Roberts, L.
core   +1 more source

Osteopontin ablation ameliorates muscular dystrophy by shifting macrophages to a pro-regenerative phenotype. [PDF]

, 2016
In the degenerative disease Duchenne muscular dystrophy, inflammatory cells enter muscles in response to repetitive muscle damage. Immune factors are required for muscle regeneration, but chronic inflammation creates a profibrotic milieu that exacerbates
Barton, Elisabeth R, Capote, Joana, Kramerova, Irina, Martinez, Leonel, Miceli, M Carrie, Spencer, Melissa J, Sweeney, H Lee, Vetrone, Sylvia   +7 more
core   +2 more sources

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

FEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet, Magali Leroy, Alexandre Maes, Ciarán Condon, Frédérique Braun   +4 more
wiley   +1 more source

Epicardial Electrical Activation During Atrial Fibrillation

JACC: Case Reports, 2019
High-definition mapping of atrial fibrillation is most commonly performed from the endocardial surface. This report describes an example of a case in which combined mapping of the endocardium and epicardium of the left atrium demonstrated electrical ...
Kathryn L. Hong, BSc, MSc, Jason Baley, BSc, Adrian Baranchuk, MD, Gianluigi Bisleri, MD, Benedict M. Glover, MD   +4 more
doaj