Results 151 to 160 of about 808,044 (306)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Patchy Earliest Activation on Near-Field Annotation Mapping: A Pitfall in Ablation of Premature Ventricular Contractions Originating From the Right Ventricular Outflow Tract. [PDF]

J Arrhythm
Sakamoto Y, Osanai H, Yoshida E.
europepmc   +1 more source

An experimental investigation of the damping contribution of an elastomeric ablator on aluminum beams [PDF]

Damping results are presented for an elastometric ablation material bonded to an aluminum alloy substrate. Tests were conducted on aluminum beams 0.159, 0.318, and 0.476 cm thick, and with and without an ablator. Ablation-material thickness varied from 0.
Howell, W. E.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Survival Benefits of Transarterial Chemoembolization Plus Ablation Therapy in Patients With Intermediate or Advanced Hepatocellular Carcinoma: A Propensity Score Matching Study

Cancer Management and Research
Jingyi Dai,1,2 Yadi Ding,1 Qiaomei Zheng,1 Guixin Zhao,1 Lingqing Zou,1 Jun Zhao,3 Yu Luo,4,* Virasakdi Chongsuvivatwong5,* 1Department of Public Laboratory, The Third People’s Hospital of Kunming/Infectious Disease Clinical Medical Center of ...
Dai J, Ding Y, Zheng Q, Zhao G, Zou L, Zhao J, Luo Y, Chongsuvivatwong V   +7 more
doaj  

Tripolar versus bipolar ablation: insights into lesion growth and geometry using a novel ablation approach for therapy-refractory ventricular arrhythmias. [PDF]

Sci Rep
Bahlke F, Abdiu E, Schultz E, Erhard N, Englert F, Duda A, Krafft H, Popa M, Syväri J, Tydecks M, Martinez AT, Reiter T, Telishevska M, Koops E, Lengauer S, Hessling G, Deisenhofer I, Spittler R.   +17 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Antitumoral immunity induced by gel ethanol ablation to treat unresectable colorectal cancer metastases in the liver. [PDF]

PLoS One
Yang J, Morhard R, Huth H, Karim B, Karanian JW, Wood BJ, Mikhail AS, Mueller JL.   +7 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Feasibility of delayed post-radiofrequency ablation biopsy in a pulmonary nodule metastatic from breast carcinoma: a case report. [PDF]

Oxf Med Case Reports
Behzad S, Shahsavani Asl A, Rouientan H, Akhlaghpoor S.   +3 more
europepmc   +1 more source