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Irreversible Electroporation [PDF]

Seminars in Interventional Radiology, 2015
Irreversible electroporation (IRE) is a predominantly nonthermal ablative technology that uses high-voltage, low-energy DC current pulses to induce cell death. Thermal ablative technologies such as radiofrequency ablation, microwave ablation, and cryoablation have several applications in oncology but have limitations that have been established. IRE has
Govindarajan Narayanan
exaly   +5 more sources

Tumor ablation with irreversible electroporation. [PDF]

PLoS ONE, 2007
We report the first successful use of irreversible electroporation for the minimally invasive treatment of aggressive cutaneous tumors implanted in mice.
Bassim Al-Sakere, Franck André, Claire Bernat, Elisabeth Connault, Paule Opolon, Rafael V Davalos, Boris Rubinsky, Lluis M Mir   +7 more
doaj   +8 more sources

Advances in irreversible electroporation for prostate cancer [PDF]

Discover Oncology
Irreversible electroporation is a nonthermal ablation technique that uses a high-voltage electric current to create nanosized pores in the cell membrane of a malignant tumor, thus resulting in cell death. In recent years, an increasing number of clinical
Xinyu Liu, Hao Wang, Zilin Zhao, Qikai Zhong, Xinlei Wang, Xing Liu, Junzhi Chen, Conghui Han, Zhenduo Shi, Qing Liang   +9 more
doaj   +4 more sources

Irreversible electroporation combined with immunotherapy versus irreversible electroporation alone for locally advanced pancreatic cancer: a systematic review and meta-analysis [PDF]

Einstein (São Paulo)
Objective: The aim of this meta-analysis was to determine the efficacy and safety of percutaneous irreversible electroporation combined with immunotherapy compared with irreversible electroporation alone in patients with locally advanced pancreatic ...
Miriana Mariussi, Laura Costa de Oliveira Lima, Mariano Gallo Ruelas, Victor Arthur Ohannesian, Bruno Murad, Guilherme Strieder de Oliveira, Luiza Giuliani Schmitt, Giovanni Brondani Torri, Stephan Altmayer, Priscila Mina Falsarella, Pedro Luiz Serrano Usón Junior, Rodrigo Gobbo Garcia   +11 more
doaj   +3 more sources

Irreversible Electroporation for Prostate Cancer [PDF]

Life, 2021
Although it can be lethal in its advanced stage, prostate cancer can be effectively treated when it is localised. Traditionally, radical prostatectomy (RP) or radiotherapy (RT) were used to treat all men with localised prostate cancer; however, this has ...
Sean Ong, Matthew Leonardo, Thilakavathi Chengodu, Dominic Bagguley, Nathan Lawrentschuk   +4 more
doaj   +4 more sources

Irreversible Electroporation in Medicine

Technology in Cancer Research and Treatment, 2007
This is a brief introduction to the emerging field of irreversible electroporation in medicine. Certain electrical fields when applied across a cell can have as a sole effect the permeabilization of the cell membrane, presumable through the formation of nanoscale defects in the cell membrane.
Boris Rubinsky
exaly   +3 more sources

Anesthesia management in oncology patients undergoing irreversible electroporation outside the operating room: a case series [PDF]

BMC Anesthesiology
Background Irreversible electroporation is a novel, non-thermal tumor ablation technique that induces cell death through electrical disruption of cellular membranes while preserving surrounding connective tissue structures.
Duygu Ozdemir Simsek, Emre Unal, Sehend Debbag, Ahmet Gudeloglu, Ayse Heves Karagoz   +4 more
doaj   +2 more sources

The Evidence of the Bystander Effect after Bleomycin Electrotransfer and Irreversible Electroporation

Molecules, 2021
One of current applications of electroporation is electrochemotherapy and electroablation for local cancer treatment. Both of these electroporation modalities share some similarities with radiation therapy, one of which could be the bystander effect.
Vitalij Novickij, Paulius Ruzgys, Saulius Šatkauskas   +2 more
exaly   +3 more sources

Stereotactic two-needle irreversible electroporation of liver tumors near critical structures: a proof-of-concept study [PDF]

European Radiology Experimental
Objective Irreversible electroporation (IRE) is a non-thermal ablation technique suitable for tumors near critical structures, but its widespread use is limited by technical complexity and the need for multiple electrodes.
Liang Zhang, Vinzenz Mayr, Lukas Luerken, Quirin Strotzer, Moritz Brandenstein, Laura Kupke, Anthony Ngu, Christian Stroszczynski, Ingo Einspieler   +8 more
doaj   +2 more sources

Cancer Cells Ablation with Irreversible Electroporation

Technology in Cancer Research and Treatment, 2005
In this study we perform in vitro irreversible electroporation (IRE) experiments with human hepatocarcinoma cells (HepG2) to investigate IRE as a new technique for undesirable tissue ablation. Irreversible electroporation (IRE) is the irreversible permeabilization of the cell membrane through the application of microsecond through millisecond ...
Liron Miller, Boris Rubinsky, Jonathan Leor   +2 more
exaly   +3 more sources