Results 1 to 10 of about 20,608 (192)

Inhibition of glucocorticoid-induced apoptosis by targeting splice variants of \u3ci\u3eBIM\u3c/i\u3e mRNA with small interfering RNA and short hairpin RNA. [PDF]

, 2004
Glucocorticoids (GCs) induce apoptosis in lymphocytes and are effective agents for the treatment of leukemia. The activated glucocorticoid receptor (GR) initiates a transcriptional program leading to caspase activation and cell death, but the critical ...
Abrams, Marc T., Robertson, Noreen M., Wickstrom, Eric, Yoon, Kyonggeun   +3 more
core   +1 more source

Nonthermal Food Processing Technologies: A Comprehensive Review

Future Postharvest and Food, EarlyView.
The graphical abstract illustrates the shift from traditional thermal food preservation methods to advanced nonthermal technologies. Traditional methods, represented by heating, often compromise the nutritional and sensory quality of foods. In contrast, nonthermal approaches such as high‐pressure processing (HPP), pulsed electric field (PEF ...
Ashok Kumar Yadav, Dinesh Chandra Rai, Aman Rathaur, Hradesh Rajput, Sudhir Kumar, Zeenat Aman   +5 more
wiley   +1 more source

Irreversible electroporation for unresectable liver malignancies

Academia Oncology
Background: Irreversible electroporation (IRE) is a non-thermal ablation technique used for liver tumors that are unresectable due to their proximity to critical structures. This study evaluates outcomes for patients treated with IRE. Methods:
Zili Zhou, Chris Wall, Jeff Bird, Shahid Ahmed, Gavin Beck, John Shaw, Michael A. J. Moser   +6 more
doaj   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Pulsed electromagnetic field therapy on nonsurgical treatment of peri‐implantitis: 12–26 months follow‐up

Journal of Periodontology, EarlyView.
Abstract Background Pulsed electromagnetic field (PEMF) therapy, renowned for its immunomodulatory effects and established efficacy in orthopedics, shows promise for managing peri‐implantitis by reducing soft tissue inflammation and marginal bone loss.
Yaniv Mayer, Eran Gabay, Amin Younis, Ofir Ginesin, Rafael S. Siroma, Shlomo Barak, Ido Georgy, Yoni Friedlander, Thabet Asbi, Hadar Giladi Zigdon, Jamil A. Shibli   +10 more
wiley   +1 more source

A novel spalt gene expressed in branchial arches affects the ability of cranial neural crest cells to populate sensory ganglia [PDF]

, 2004
Cranial neural crest cells differentiate into diverse derivatives including neurons and glia of the cranial ganglia, and cartilage and bone of the facial skeleton.
Barembaum, Meyer, Bronner-Fraser, Marianne   +1 more
core   +1 more source

Endoscopic small bowel therapies for type 2 diabetes

Nutrition in Clinical Practice, EarlyView.
Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel, Zehra Naseem, Prisha Gattu, Stephen Firkins, Roberto Simons‐Linares   +4 more
wiley   +1 more source

Careful treatment planning enables safe ablation of liver tumors adjacent to major blood vessels by percutaneous irreversible electroporation (IRE)

Radiology and Oncology, 2015
Background. Irreversible electroporation (IRE) is a tissue ablation method, which relies on the phenomenon of electroporation. When cells are exposed to a sufficiently electric field, the plasma membrane is disrupted and cells undergo an apoptotic or ...
Kos Bor, Voigt Peter, Miklavcic Damijan, Moche Michael   +3 more
doaj   +1 more source

Modelling the positioning of single needle electrodes for the treatment of breast cancer in a clinical case [PDF]

, 2015
Background: Breast cancer is the most common cancer in women worldwide and is the second most common cause of cancer death in women. Electrochemotherapy (ECT) used in early-phase clinical trials for the treatment of primary breast cancer resulted in a ...
Claudio, Botti, Denzi, Agnese, Franco Di, Filippo, Letizia, Perracchio, Liberti, Micaela, Lidia, Strigari, Mattia, Ronchetti, Ruggero, Cadossi, Simona Di, Filippo   +8 more
core  

The relationship between membrane damage, release of protein and loss of viability in Escherichia coli exposed to high hydrostatic pressure [PDF]

, 2010
The aim of this work was to examine a possible association between resistance of two Escherichia coli strains to high hydrostatic pressure and the susceptibility of their cell membranes to pressure-induced damage. Cells were exposed to pressures between
Klotz, Bernadette, Mackey, Bernard M., Manas, Pilar   +2 more
core   +1 more source