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Electrochemotherapy Using Doxorubicin and Nanosecond Electric Field Pulses: A Pilot in Vivo Study

open access: yesMolecules, 2020
Pulsed electric field (PEF) is frequently used for intertumoral drug delivery resulting in a well-known anticancer treatment—electrochemotherapy. However, electrochemotherapy is associated with microsecond range of electrical pulses, while nanosecond ...
Vitalij Novickij   +2 more
exaly   +5 more sources

Histopathological findings in colorectal liver metastases after electrochemotherapy. [PDF]

open access: yesPLoS ONE, 2017
Electrochemotherapy of colorectal liver metastases has been proven to be feasible, safe and effective in a phase I/II study. In that study, a specific group of patients underwent two-stage operation, and the detailed histopathological evaluation of the ...
Gorana Gasljevic   +6 more
doaj   +2 more sources

Treatment of vulvar cancer recurrences with electrochemotherapy – a detailed analysis of possible causes for unsuccessful treatment [PDF]

open access: yesRadiology and Oncology, 2023
Electrochemotherapy has good local effectiveness in the treatment of vulvar cancer. Most studies have reported the safety and effectiveness of electrochemotherapy for palliative treatment of gynecological cancers and mostly vulvar squamous cell carcinoma.
Vivod Gregor   +7 more
doaj   +2 more sources

Effects of Electrochemotherapy on Immunologically Important Modifications in Tumor Cells [PDF]

open access: yesVaccines, 2023
Electrochemotherapy (ECT) is a clinically acknowledged method that combines the use of anticancer drugs and electrical pulses. Electrochemotherapy with bleomycin (BLM) can induce immunogenic cell death (ICD) in certain settings.
Ursa Kesar   +6 more
doaj   +2 more sources

Safety and Feasibility of Analgosedation for Electrochemotherapy of Liver Lesions

open access: yesLife, 2023
Interventional Oncology treatments grant low-risk mini-invasive alternatives to surgery for cancer patients. Percutaneous ablative therapies represent a cornerstone for treatment of liver cancer patients.
Roberto Iezzi   +9 more
doaj   +2 more sources

Differential cellular effects of electroporation and electrochemotherapy in monolayers of human microvascular endothelial cells. [PDF]

open access: yesPLoS ONE, 2012
In vivo electroporation of tumours shows disruption of blood flow and creates a vascular effect with an initial rapid and transient vasoconstriction phase and a much longer lasting phase with changed microvascular endothelium.
Cécil J W Meulenberg   +2 more
doaj   +2 more sources

The Rising Power of Electrochemotherapy in Musculoskeletal Oncology [PDF]

open access: yesCurrent Oncology
Electrochemotherapy is a minimally invasive treatment based on the principle of reversible electroporation of target cells in pathologic tissues in order to increase the local effect of chemotherapeutic agents.
Nicolas Papalexis   +9 more
doaj   +2 more sources

Electrochemotherapy Combined With Immunotherapy – A Promising Potential in the Treatment of Cancer

open access: yesFrontiers in Immunology
Electrochemotherapy is a novel, locoregional therapy that is used to treat cutaneous and deep-seated tumors. The electric pulses used in electrochemotherapy increase the permeability of the cell membranes of the target lesion and thus enhance the ...
Masa Omerzel, Maja Cemazar, Gregor Sersa
exaly   +3 more sources

Electrochemotherapy in the treatment of basal cell carcinoma of the head and neck: a case report [PDF]

open access: yesJournal of Medical Case Reports
Background Skin areas chronically exposed to solar radiation, such as the face, neck, scalp, and upper limbs, are at significantly increased risk of developing basal cell carcinoma.
Gianluca Nicolai   +4 more
doaj   +2 more sources

Electrochemotherapy of spinal metastasis using transpedicular approach: a preclinical safety animal study [PDF]

open access: yesEuropean Radiology Experimental
Background Electrochemotherapy (ECT) of vertebral metastasis is a new treatment option for metastasis that is not accessible to thermal ablation or radiotherapy.
Frederic Deschamps   +8 more
doaj   +2 more sources

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