Results 31 to 40 of about 5,662 (220)

Response dataset from canine extramedullary plasmacytoma treated with lipophobic drugs enhanced by electroporation

Data in Brief, 2020
Over the past 15 years, lipophobic drugs, such as bleomycin and cisplatin, have been used combined with electroporation, which promotes their uptake through the cell membrane.
Denner Santos dos Anjos, Ygor Amaral Rossi, Oscar Rodrigo Sierra, Cynthia Marchiori Bueno, Andrigo Barboza De Nardi, Carlos Eduardo Fonseca-Alves   +5 more
doaj   +1 more source

Synergistic Combination of Electrolysis and Electroporation for Tissue Ablation. [PDF]

PLoS ONE, 2016
Electrolysis, electrochemotherapy with reversible electroporation, nanosecond pulsed electric fields and irreversible electroporation are valuable non-thermal electricity based tissue ablation technologies. This paper reports results from the first large
Michael K Stehling, Enric Guenther, Paul Mikus, Nina Klein, Liel Rubinsky, Boris Rubinsky   +5 more
doaj   +1 more source

Successful electrochemotherapy treatment of a large bleeding lymph node melanoma metastasis

Melanoma Management, 2022
Despite the progress in immunotherapy and targeted therapy for patients with cutaneous malignant melanoma not all patients with loco-regional recurrences will respond to treatment.
Fredrik J Landström, Frida E Jakobsson, Stefan J Kristiansson   +2 more
doaj   +1 more source

Electropermeabilization of inner and outer cell membranes with microsecond pulsed electric field. Quantitative study with calcium ions [PDF]

, 2017
Microsecond pulsed electric fields (mu sPEF) permeabilize the plasma membrane (PM) and are widely used in research, medicine and biotechnology. For internal membranes permeabilization, nanosecond pulsed electric fields (nsPEF) are applied but this ...
Andrã©, Franck M., Denzi, Agnese, Hanna, Hanna, Liberti, Micaela, Mir, Lluis M.   +4 more
core   +2 more sources

Effect of electrode distance in grid electrode: Numerical models and in vitro tests [PDF]

, 2018
Electrochemotherapy is an emerging local treatment for the management of superficial tumors and, among these, also chest wall recurrences from breast cancer.
3,, 3, Md2, Bernardello, Clara, DE MATTEI, Monica, Di Barba, Paolo, Dughiero5, Fabrizio, Elisabetta Sieni, And, Evelina Mognaschi, Maria, Forzan, Michele, Giovanni Campana, Luca, Ongaro, Alessia, Pellati, Agnese, Phd,, Phd1,, Phd1,, Phd1,, Phd2, Md, Phd4,, Phd4,, Phd5,, Phd5,, Riccardo Rossi, Carlo   +21 more
core   +1 more source

Electrochemotherapy: Progress and Prospects

Current Pharmaceutical Design, 2012
Treatment of recurrent or unresectable cutaneous and subcutaneaous tumors continues to be a major therapeutic challenge. Electrochemotherapy (ECT) is a palliative treatment of cutaneous and subcutaneous tumor nodules for which standard treatments (e.g. radiotherapy, chemotherapy, and surgery) have failed or proved to be insufficient.
Escoffre, Jean-Michel, Rols, Marie-Pierre   +1 more
openaire   +5 more sources

Bleomycin Concentration in Patients’ Plasma and Tumors after Electrochemotherapy. A Study from InspECT Group

Pharmaceutics, 2021
The plasma concentration profile of bleomycin in the distribution phase of patients younger than 65 years is needed to determine the suitable time interval for efficient application of electric pulses during electrochemotherapy.
Ales Groselj, Masa Bosnjak, Mojca Krzan, Tina Kosjek, Kriszta Bottyán, Helena Plesnik, Crt Jamsek, Maja Cemazar, Erika Kis, Gregor Sersa   +9 more
doaj   +1 more source

Technological and theoretical aspects for testing electroporation on liposomes [PDF]

, 2017
Recently, the use of nanometer liposomes as nanocarriers in drug delivery systems mediated by nanoelectroporation has been proposed. This technique takes advantage of the possibility of simultaneously electroporating liposomes and cell membrane with 10 ...
Apollonio, Francesca, Denzi, Agnese, Esposito, Gianluca, Liberti, Micaela, Mir, Lluis M., Valle, Elena Della   +5 more
core   +3 more sources

Recent Advances in Electrochemotherapy

Bioelectricity, 2019
Electrochemotherapy is gaining recognition as an effective local therapy that uses systemically or intratumorally injected bleomycin or cisplatin with electroporation as a delivery system that brings drugs into the cells to exert their cytotoxic effects.
Maja, Cemazar, Gregor, Sersa
openaire   +3 more sources

Electrochemotherapy vs radiotherapy in the treatment of primary cutaneous malignancies or cutaneous metastases from primary solid organ malignancies: A systematic review and narrative synthesis.

PLoS ONE, 2023
BackgroundElectrochemotherapy has gained international traction and commendation in national guidelines as an effective tool in the management of cutaneous malignancies not amenable to surgical resection.
Angus Torry McMillan, Luke McElroy, Lorcan O'Toole, Paolo Matteucci, Joshua Philip Totty   +4 more
doaj   +1 more source